THE PREVALENCE OF BACTERIA ISOLATED FROM BLOOD CULTURES OF IRANIAN CHILDREN AND STUDY OF THEIR ANTIMICROBIAL SUSCEPTIBILITIES

authors:

avatar E Kalantar 1 , * , avatar M Motlagh 2 , avatar H Lordnejad 2 , avatar S Beiranvand 3 , avatar 4

Kurdistan Digestive Research Center, Kurdistan University of Medical Sciences, ekalantar@hotmail.com, Iran
Family Health and Population, Ministry of Health and Medical Education, Iran
Food and Drug Department, Kurdistan University of Medical Sciences, Iran
Jundishapur Journal of Natural Pharmaceutical Products: Vol.3, issue 1; 1-7
article type: Research Article
received: October 13, 2008
accepted: February 2, 2009

how to cite: Kalantar E, Motlagh M, Lordnejad H, Beiranvand S, . THE PREVALENCE OF BACTERIA ISOLATED FROM BLOOD CULTURES OF IRANIAN CHILDREN AND STUDY OF THEIR ANTIMICROBIAL SUSCEPTIBILITIES. Jundishapur J Nat Pharm Prod. 2008;3(1): 1-7. 

Abstract

Infections cause significant mortality and morbidity in children. Although there are various antibiotics that can be used to combat bloodstream infection, resistant strains have subsequently emerged.             A prospective study was carried out for one month period in 55 hospitals from 12 provinces representing different geographical areas in Iran. The aim was to determine the pattern of pathogens and their antimicrobial sensitivity among children. Of 1143 blood specimens tested from various hospitals, bacteria were isolated from 715 of children from one month to three years old age. The predominant isolated pathogens from blood specimens were Gram-positive bacteria in 301 (65.25%) patients, mainly 198 (65.78%) coagulase-negative Staphylococci. The Gram-negative bacteria were 140 (31.74%). About 66% of the Gram-positive bacteria were coagulase-negative Staphylococci, while the gram-negative bacteria were mainly (Escherichia coli, Enterobacter spp, Klebsiella pneumoniae, and Pseudomonas spp.). The majority of S. aureus were resistant to Oxacillin, Co-trimoxazole, Cephalotin, and Ampicillin. About two – third of the E. coli and K. pneumonia were resistant to Cephalotin.

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