BENEFICIAL EFFECTS OF SOYPROTEIN ISOFLAVONES ON LIPID AND BLOOD GLUCOSE CONCENTRATIONS IN TYPE 2 DIABETIC SUBJECTS

Authors

H.B Shahbazian1,*, R Amani2, J Siadatan2, H Shahbazian2, M Latifi2, A Ahmadzadeh2, M Haghighizadeh2
1Endocrine Department, Golestan Hospital, Ahwaz Jundishapur University of Medical Sciences, [email protected]
2School of Paramedical Sciences, Ahwaz Jundishapur University of Medical Sciences
*Corresponding Author: Endocrine Department, Golestan Hospital, Ahwaz Jundishapur University of Medical Sciences, [email protected]. Email: [email protected]

Jundishapur Journal of Natural Pharmaceutical Products:Vol. 1, issue 1; 48-52
Published online:Dec 20, 2006
Article type:Research Article
Received:Feb 10, 2006
Accepted:Nov 23, 2005
How to Cite:Shahbazian H, Amani R, Siadatan J, Shahbazian H, Latifi M, et al. BENEFICIAL EFFECTS OF SOYPROTEIN ISOFLAVONES ON LIPID AND BLOOD GLUCOSE CONCENTRATIONS IN TYPE 2 DIABETIC SUBJECTS. Jundishapur J Nat Pharm Prod. 2006;1(1):. doi:

Abstract

Consumption of soyprotein has recently been shown to improve the blood lipid levels in  non-diabetic subjects. The purpose of this study was to evaluate if a dietary soyprotein isoflavones affects lipid and blood glucose levels in type 2 diabetic subjects. Twenty six type 2 diabetic patients who had refferd to Ahvaz Jundishapour University Diabetes Center, due to uncontrolled diabetes, participated in this study. They completed a trial of dietary supplementation with 25gr/day of a processed defeated meal containing 12 gr soyprotein and about 50mg isoflavones, for 3 months. FBS, HbA1C, serum total cholesterol, triglyceride, HDL and LDL-C and patients, weight and blood pressure were checked before soyprotein consumption and monthly thereafter. There were significant differences in mean FBS (153±50 versus 178±60, P< 0.015), HbA1C (8.8 ± 1.4 versus 9.6 ± 1.7 percent, P<0.001), triglycerides concentration (229 ± 113 versus 267 ± 149 P<0.008) and total cholesterol (196 ± 41 versus 207 ± 42, P<0.002) before and after three months consumption of soyprotein isoflavones.There were no significant changes in HDL and LDL-C cholesterol levels, blood pressure and weight.

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© 2006, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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