BENEFICIAL EFFECTS OF SOYPROTEIN ISOFLAVONES ON LIPID AND BLOOD GLUCOSE CONCENTRATIONS IN TYPE 2 DIABETIC SUBJECTS

authors:

avatar H.B Shahbazian 1 , * , avatar R Amani 2 , avatar J Siadatan 2 , avatar H Shahbazian 2 , avatar M Latifi 2 , avatar A Ahmadzadeh 2 , avatar M Haghighizadeh 2

Endocrine Department, Golestan Hospital, Ahwaz Jundishapur University of Medical Sciences, Hjb_shahbazian@yahoo.com
School of Paramedical Sciences, Ahwaz Jundishapur University of Medical Sciences

How To Cite Shahbazian H, Amani R, Siadatan J, Shahbazian H, Latifi M, et al. BENEFICIAL EFFECTS OF SOYPROTEIN ISOFLAVONES ON LIPID AND BLOOD GLUCOSE CONCENTRATIONS IN TYPE 2 DIABETIC SUBJECTS. Jundishapur J Nat Pharm Prod. 2006;1(1): 48-52. 

Abstract

Consumption of soyprotein has recently been shown to improve the blood lipid levels in  non-diabetic subjects. The purpose of this study was to evaluate if a dietary soyprotein isoflavones affects lipid and blood glucose levels in type 2 diabetic subjects. Twenty six type 2 diabetic patients who had refferd to Ahvaz Jundishapour University Diabetes Center, due to uncontrolled diabetes, participated in this study. They completed a trial of dietary supplementation with 25gr/day of a processed defeated meal containing 12 gr soyprotein and about 50mg isoflavones, for 3 months. FBS, HbA1C, serum total cholesterol, triglyceride, HDL and LDL-C and patients, weight and blood pressure were checked before soyprotein consumption and monthly thereafter. There were significant differences in mean FBS (153±50 versus 178±60, P< 0.015), HbA1C (8.8 ± 1.4 versus 9.6 ± 1.7 percent, P<0.001), triglycerides concentration (229 ± 113 versus 267 ± 149 P<0.008) and total cholesterol (196 ± 41 versus 207 ± 42, P<0.002) before and after three months consumption of soyprotein isoflavones.There were no significant changes in HDL and LDL-C cholesterol levels, blood pressure and weight.

Full Text

Full text is available in PDF