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Jundishapur Journal of Natural Pharmaceutical Products
The Official Journal of Ahvaz Jundishapur University of Medical Sciences
e-ISSN 2228-7876
p-ISSN 1735-7780
ISOLATION OF A NEW MODERATELY HALOPHILIC BROAD-SPECTRUM ANTIBIOTIC PRODUCING ACTINOBACTER
Authors
1Microbial Biotechnology laboratory, Department of Microbiology, School of Biology, College of Science, University of Tehran, [email protected], Iran
2Microbial Biotechnology laboratory, Department of Microbiology, School of Biology, College of Science, University of Tehran, Iran
*Corresponding Author: Microbial Biotechnology laboratory, Department of Microbiology, School of Biology, College of Science, University of Tehran, [email protected], Iran. Email: [email protected]
Published online:Nov 30, 2007
Article type:Research Article
Received:Jun 26, 2007
Accepted:Nov 29, 2007
How to Cite:Hamedi J, Mohammadipanah F, Amoozegar M, Dehghan S. ISOLATION OF A NEW MODERATELY HALOPHILIC BROAD-SPECTRUM ANTIBIOTIC PRODUCING ACTINOBACTER. Jundishapur J Nat Pharm Prod. 2007;2(2):. doi:
Abstract
In a screening program for antibiotic producer rare-actinobacteria from soil of Iran, a novel moderately halophilic actinobacter (Q70) was isolated. The strain had the ability of antibiotic production against methicillin resistant Staphylococcus aureus. Maximum antibiotic production was obtained in the medium containing 10% (w/v) NaCl. The strain Q70 had also activity against Enterococcus faecalis, Bacillus subtilis and Pseudomonas aeruginosa. The antibiotic extracted from fermentation broth had low toxicity (681/3 μg/ml LC50) against Artemia salina in brine shrimp lethality test. The antibiotic produced by strain Q70 had polar structure. The strain Q70 is proposed as a new species with the name of Nocardiopsis iraniensis with considering the significant morphological, physiological, molecular and chemotaxonomical differences between Q70 and other species of Nocardiopsis.
Copyright
© 2007, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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