Effects of Berberise Vulgaris Fruit extract on blood cholesterol and triglyceride in hyperlipidemic patients

authors:

avatar abolfazl farhadi , * , avatar Kehzad JavadiFar , avatar Abolghasem Farhadi


how to cite: farhadi A , JavadiFar K, Farhadi A. Effects of Berberise Vulgaris Fruit extract on blood cholesterol and triglyceride in hyperlipidemic patients. koomesh. 2008;9(3):e152193. 

Abstract

Introduction: Previous studies have indicated that aqueous extract of Berberise Vulgaris (BV) has ability to decrease plasma levels of lipids probably via stimulating lipolysis pathways in liver. The aim of this study was to determine the effects of BV Fruit extracts on plasma levels of cholesterol and triglyceride. Materials and Methods: In this semi-experimental study, 89 patients who suffering from hypercholesterolemia and hyper-triglyceridemia were taken and divided into case and control group using a random pattern. The case group was received aqueous extract of fruit of BV and the control group received a placebo at the same volume. Fasting blood sample was drawn for measurement of cholesterol and triglycerides. Data were analyzed with student t- test. Results: Results showed that extract of BV fruits significantly decreased the amount of total blood cholesterol and triglyceride in case group as compared with control group (P