Synthesis of ZnO:Mg nanoparticle with sol-gel method and its antimicrobial efficacy against Listeria Monocytogenes PTCC 1294 (Serotype 1a)

Nima Shadan; Khosro Issazadeh; Mahdi Shahriarinour; Ali Abdollahzadeh; Fared Azizi Jalilian; Hadi Hasanzadeh; Sona Dalilan

doi:10.5812/koomesh-153896

Koomesh

Journal of Semnan University of Medical Sciences

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Synthesis of ZnO:Mg nanoparticle with sol-gel method and its antimicrobial efficacy against Listeria Monocytogenes PTCC 1294 (Serotype 1a)

Author(s):

Nima Shadan¹,

Khosro Issazadeh

^2,*,

Mahdi Shahriarinour

¹,

Ali Abdollahzadeh³,

Fared Azizi Jalilian⁴,

Hadi Hasanzadeh⁵,

Sona Dalilan⁶

1Dept. of Microbiology, Islamic Azad University, Rasht Branch, Guilan, Iran

2Dept. of Microbiology, Islamic Azad University, Lahijan Branch, Guilan, Iran

3Dept. of Physics, Nano Research Lab, Islamic Azad University, Lahijan Branch, Guilan, Iran

4Dept. of Microbiology, Hamedan University of Medical Sciences, Hamedan, Iran

5Dept. of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran

6Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Koomesh:Vol. 16, issue 2; e153896

Published online:Aug 21, 2015

Article type:Research Article

How to Cite:Nima ShadanKhosro IssazadehMahdi ShahriarinourAli AbdollahzadehFared Azizi JalilianHadi HasanzadehSona Dalilanet al.Synthesis of ZnO:Mg nanoparticle with sol-gel method and its antimicrobial efficacy against Listeria Monocytogenes PTCC 1294 (Serotype 1a).koomesh.16(2):e153896.

Abstract

Introduction: Listeria monocytogenes is the disease agent of listeriosis and creates primary meningitis, septicemia and food poisoning in due to consumption dairy in adults. In pregnant women usually causesbacterimia that lead to inflammation of the placenta, fetal infection and eventually abortion. Since today strains of L.monocytogenes have progressivily become resistant to various antibiotics and the antimicrobial materials, this makes it necessary to synthesize the nanopaticle which have antimicrobial effects. Purpose of this study was also to synthesize ZnO nanoparticle with magnesium doping (ZnO:Mg) and investigate its inhibitory effect on L.monocytogenes. Materials and Methods: ZnO:Mg nanoparticle were prepared and synthesized using Sol-Gel method in Atomic Percents of 1%, 3%, 5%, 7%. Tests of XRD and transmission electron microscopy performed in order to study the structure of the nanoparticle and evaluation its quality and also measurement of Optical density and scanning electron microscopy was used to study antimicrobial effect of nanoparticle. Results: The results obtained from measurement of optical density and scanning electron microscopy showed that depending on the parameters of nanoparticle dilutions, atomic percent, temperature and duration, the amount of bacteria colonies has been significantly and mainly decreased and inhibited. Conclusion: Due to the growing trend of drug resistance, suitable structural characteristics and purity crystalline nanoparticles ZnO:Mg, it can be inoculated, particularly in atomic percentages of 5% and 7% for the inhibition and destruction of L.monocytogenes.

Keywords

ZnO nanoparticle

Mg

Listeria monocytogenes

Sol-Gel Method

Optical Density

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