Understanding anxiety as the most common mental disorder in Iran and its psychological changes (
1,
2) is very important. In particular, anxiety symptoms are very common during the Coronavirus disease 2019 (COVID-19) (
3,
4), which can be a threat to people's mental health. People with high levels of coronavirus anxiety report more coronavirus fear, functional impairment, worry about coronavirus, maladaptive religious coping, hopelessness, and suicidal ideation (
5,
6).
Also, increased anxiety level during the coronavirus pandemic has a key role in substance abuse (
7) and can moderate the degree of drug craving in response to induced negative effects (
8). Levels of Anxiety may be important not only for understanding drug use patterns (
9,
10), but also psychiatric burden and severity of medical complaints that co-occur with drug use disorders. Regarding these relationships in a substance-abusing sample (
11), it was found that increased anxiety was associated with increased medical and psychiatric complications associated with substance abuse (as assessed via the Addiction Severity Index (
12). On the other hand, since substance use disorder (SUD) is associated with a variety of cardiovascular and metabolic diseases, it is probable that people with SUD are exposed to COVID-19 risk (
13). Substance use is relatively high, and its overuse can cause hypoventilation and hypoxemia followed by cardiopulmonary and neurological complications and worsening COVID-19 consequences (
14). In dealing with issues in acute conditions, affecting coping, adaptability, and the ability to overcome the existing problems are important (
15). Therefore, it is necessary to identify factors that predict COVID-19-induced anxiety in drug users.
Research regarding the development of anxiety has focused on genetic factors (
16), specific types of learning experiences (
17), and attachment styles (
18). The concept of attachment styles is one of the psychological factors that influence anxiety resulting from the coronavirus pandemic (
19). Due to uncertainty resulting from the pandemic, people probably need more safety and security (
20). However, insecurities about the sudden coronavirus outbreak may be exacerbated and make more insecure people less supportive of their position. For this reason, perceived risks from people simulate attachment motivational system. This is a common image that adults with a secure attachment style are more flexible in stressful situations and show adaptive coping strategies (
15,
21). In support of this view, international studies have found that secure attachment is protective against post-traumatic stress symptoms (
22). Insecure attachment is associated with increased perceived stress, somatization disorders, and negative emotions (
23-
25). Another study found that a secure attachment style reduces anxiety caused by coronavirus (
26).
Recently, resilience has gained popularity as a protective agent in critical conditions (
27). Resilience refers to keeping sustainable and healthy performance after a potentially vulnerable event and is a dynamic process that includes positive adaptation in facing adversities (
28). Masten (2018) defines resilience as an apparent capacity potential of a dynamic system for successful adaptation to disorders that threaten the performance, survival, or development of the system (
29). The American Psychological Association (APA) defines resilience as a process to return from difficult experiences and good adaptation against adversities, trauma, tragedy, threats, or important sources of stress (
30). The importance of this concept results from its direct connection with the ability to respond effectively to sudden events (
31). In a recent study, resilience and individual well-being have been identified as the most important COVID-19 anxiety predictors. Evidences from another study point to a negative relationship between resilience and COVID-19-induced anxiety (
32,
33).
Expectancy is another source of adaptation and resilience that can lead to improved mental health during a health-related global crisis (
34). The widest expectancy model defines this construct as a cognitive characteristic that indicates the perceived capacity to identify ways or strategies to achieve goals or incentives to follow goals of interest (
35). Expectancy is conceptualized source that provides a tool to cope with conditions that seem uncontrollable (
36). Studies have shown that people with high life expectancy, contrary to people with low life expectancy, probably adapt to life challenges and employ effective coping strategies against difficulties (
36,
37). Accordingly, expectancy may increase positive emotion, satisfaction, and success while following goals, especially during stressful moments. Although studies on COVID-19 are completely new, at least two studies (
34,
38) have shown that expectancy may be associated with flexibility in facing acute stressful factors related to the COVID-19 pandemic and can play a role in overcoming anxiety resulting from this crisis. In a prospective cohort study, researchers concluded that expectancy is associated with physical health, health behaviors, and many psychological and social dimensions (
39).
Considering the long-term prevalence of COVID-19 and increased anxiety levels because of increasing drug abuse (
7), it is necessary to pay attention to mental health, one of the present era (
40), and its promotion in drug users.
Considering the long-term prevalence of COVID-19 epidemics, increasing the level of anxiety and consequently increasing the prevalence of drug abuse (
7), it is necessary to pay more attention to mental health, which is one of the important goals of psychology in the present century (
40), and the main concern is for those who are currently using drugs and those who are in the recovery period and are completely isolated from society. Feeling COVID-19-induced anxiety may even prevent addicts from going to an addiction clinic to start or continue treatment while starting or continuing treatment is key to their lives. In this regard, no study has investigated the predictive role of COVID-19-induced anxiety based on attachment, resilience, and expectancy styles of people who use drugs.