Keywords
Dear Editor,
We thank the authors for their interest and comments on our manuscript (1). As it was mentioned by the authors, apparently more frequent diagnosis of tuberculosis in warm seasons may be a reflection of more frequent acquisition of organism during cold seasons, which is due to crowding, low immunity and low level of vitamin D, and less diagnostic confusion with common upper respiratory tract infection (2, 3). However, due to the design of our study, which was retrospective and also poor recording of patient initiation symptom in our registry, we could not find the exact causes of seemingly tuberculosis diagnosis in warm seasons.
References
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1.
Sahraei Z, Niknami E, Saffaei A. Comment on: "Pulmonary tuberculosis seasonality survey in Fars Province, South of Iran". Shiraz E-Med J. e97381. https://doi.org/10.5812/semj.97381.
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2.
Willis MD, Winston CA, Heilig CM, Cain KP, Walter ND, Mac Kenzie WR. Seasonality of tuberculosis in the United States, 1993-2008. Clin Infect Dis. 2012;54(11):1553-60. [PubMed ID: 22474225]. [PubMed Central ID: PMC4867465]. https://doi.org/10.1093/cid/cis235.
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Koh GC, Hawthorne G, Turner AM, Kunst H, Dedicoat M. Tuberculosis incidence correlates with sunshine: an ecological 28-year time series study. PLoS One. 2013;8(3). e57752. [PubMed ID: 23483924]. [PubMed Central ID: PMC3590299]. https://doi.org/10.1371/journal.pone.0057752.