The results of the current study showed that the knowledge score of the studied population was 73.73 out of 100. A study conducted using an online questionnaire revealed that the knowledge level of the American and British people about the ways of transmission and the symptoms of COVID-19 was appropriate. However, there have been various misunderstandings about the methods of causing the disease, which is being shared on social media (
28). Therefore, although the knowledge level about the disease is relatively good, training should be continued.
Moreover, the present study indicated that social media is the most important source of information about COVID-19 for the studied population. Social media can be an excellent option to manage and control COVID-19 through public knowledge raising. According to the literature in this field, specialists can prevent the spread of epidemics by identifying the needs of social media users and providing appropriate public health training, and they can use social media in the disease control and management plans (
29).
We found no significant relationship between the knowledge of social media users about COVID-19 and the variables of gender and marital status. Due to the high accessibility of smartphones, many people in the community use mobile phones and social media, such as WhatsApp, Telegram, and Instagram, to be aware of topics (
30,
31). There is no difference between men and women in access to smartphones and social media, and the most popular social media can be used to raise knowledge and inform people.
Furthermore, our results demonstrated a significant relationship between the knowledge level of users and educational level as there was a significant difference between a Master's degree and high school and under high school degrees. However, some investigations showed no difference between individuals at different educational levels in terms of concern about the risk of developing COVID-19 (
32). People with higher levels of education, due to their ability to retrieve relevant and valid information when using social media, can obtain the required information on various topics, including personal and social health. Therefore, they can prevent developing diseases and help to break the transmission chain. It is also suggested that due to the variable levels of individuals' education in the community, the producers of educational content on social media in coping with COVID-19 should pay attention to the needs of all individuals in the community. Meanwhile, UNICEF has also emphasized providing health training related to COVID-19 for students based on their level of education (
33).
The results of the current study showed that users’ knowledge level about COVID-19 had a significant relationship with individuals' professions as there was a significant difference between the mean knowledge score of people with governmental jobs and unemployed people. In addition, there was a significant difference between students' knowledge and unemployed people. Implementing comprehensive programs, such as social distancing, is one of the critical and practical points in managing and controlling COVID-19 (
34,
35). In implementing this plan, required and specific training should be provided based on the types of professions and their activities. In order to successfully develop the social distancing program, it is suggested to prepare training materials and resources related to various occupations and provide to people through social media as the most important source of information.
Other findings of the present research revealed that one of the challenges of knowledge raising for social media users is related to the nature of COVID-19. Emergence, being unknown, information shortage about prevention methods, and the frequent information changes about this disease can make any kind of knowledge raising difficult. Information about the disease changes is published daily and in various articles. For example, there were numerous discussions concerning the effectiveness of quarantine, and there were different opinions (
36). There were also various debates about masks by a healthy population, all of which are related to the emergence of the disease and the unknown aspects of prevention and control. WHO stated that the mechanism of disease transmission by asymptomatic individuals is still unknown. Information on transmission methods is still being developed, and research in this field continues (
37).
The findings of the present study also showed that media literacy is the most important users-related challenge. Regarding media literacy, the results of various studies are controversial. In some studies, the level of media literacy among individuals was reported to be above average (
38,
39), while in another investigation, it was reported to be inappropriate (
40). Further studies on media literacy, especially health-related media literacy, are suggested. Consequently, educational planning and public knowledge raising can be performed, and required decisions can be made. The inclusion of media literacy training in the school curriculum is also recommended. In this regard, the Ministry of Education published a book entitled Media Thinking and Literacy in the 2016 - 2017 academic year (
41). However, producing more and more comprehensive educational content for all levels of students is needed.
Stewardship challenges are among other current challenges in Iran's health system for raising the knowledge of social media users. In the previous studies, the stewardship weakness in Iran's health system (
42) and the infectious diseases care system (
43,
44) has been emphasized, which is consistent with the results of the present study. It is suggested that in order to face this challenge properly, popular channels be identified and certified. Next, appropriate and up-to-date content is produced and provided. It is also recommended that, in accordance with the dimensions of stewardship, policy-making in the face of crises be evidence-based, and intra-sectoral governance of the health system be examined, assessed, and reformed. Moreover, special attention should be given to inter-sectoral leadership focusing on the Ministry of Health.
Some other knowledge-raising challenges were related to the inherent characteristics of social media. The interviewees ' concerns were the speed of message transmission, high information volume, unscientific orientation, and the lack of time limit in producing and using the information on social media. According to the cognitive load theory and dual coding theory, the high speed of message transmission and high information volume on social media may lead to less retention of messages. Therefore, it is necessary to increase the attractiveness of messages on social media to augment the likelihood of retention; for example, designing messages using infographics and images can be helpful (
45).
The weakness of domestic messengers was another challenge in raising the knowledge of social media users highlighted by the study participants. The participants cited the weakness of domestic messengers as the reason for their unpopularity. In a study conducted by Delshadi et al. in 2016, it was found that students used foreign social media, and none of them used domestic ones (
46). Due to the low acceptance of domestic social media, it is suggested that during the outbreak of diseases, the Ministry of Health, medical sciences universities, and health networks of the cities play an active role in other widely used social media.
The current study had some limitations. First, the participants in the study may not be fully representatives of those citizens of Khorramabad who use social media. People who tend to participate in studies have better health status and higher health literacy. Since the participants were not randomly selected, some overestimation in the knowledge score is expected. Second, the relatively small sample size of the study can lead to a random error in the study. Therefore, the study power in differentiating differences and relationships decreases. Despite the challenges in using social media for raising knowledge about COVID-19, with proper and active management of social media and a decisive and effective presence of health care authorities in social media, this platform can be the most important source of public knowledge raising during the outbreak of infectious diseases.