This study was done using two consecutive methods on the researchers of Shiraz University of Medical Sciences. First, a qualitative study was conducted using face-to-face interview with 22 researchers with professor academic rank who had at least 50 research projects and had performed the largest number of research projects in various fields. This interview was semistructured with open-ended questions. At the beginning of each interview, participants were informed that this study was to find their experiences regarding the research problems. They were also assured about the confidentiality and nondisclosure of the personal information. In addition, verbal consent for recording the interview content was obtained from the participants. Each interview was done in the Office of Research and Technology of Shiraz University of Medical Sciences and lasted for 30 to 50 minutes. Selection of new participants was continued until data saturation, ie, no new or relevant information emerges. The interviews were arranged according to the participants’ interests in field and ranged from a day to a month. If the participants felt tired or did not provide further information, the interview was ended and its continuation depended on the participants’ interest. Each interview was tape-recorded and field notes were written and reviewed several times after each interview. After the interview, the important segmentation of the data that were related to the participants’ experience was specified, the themes were identified and clustered, and the core variables of the most frequent themes were obtained. Using these themes and core variables, we designed a questionnaire containing 37 questions. The first part of the questionnaire contained the demographic information, including age, sex, level of education, faculty position, workplace, field of study, and the number of projects and papers. The second part of the questionnaire included questions, problems, and barriers to research that were classified as very important (score, 5), important (score, 4), modest (score, 3), unimportant (score, 2), and very unimportant (score, 1). The questions were categorized into three areas of management-organizational, financial-equipment, and personal-professional. Management-organizational area included administrative and management barriers. Financial-equipment area involved equipment and economic barriers. Finally, personal-professional area included individual, social, and professional barriers. According to Cronbach's alpha test, the reliability of this questionnaire was 96%. In addition, its face validity was approved by the specialists in this field and the Deputy of Research Affairs. In the second phase of the study, the questionnaire was completed by 105 official and contractual faculty members. Samples were collected from School of Medicine, School of Allied Health, Faculty of Nursing, School of Management, School of Dentistry, Department of Rehabilitation, Faculty of Pharmacy, School of Public Health and Nutrition, Gerash School of Allied Health, and Hazrat-e-Zainab Faculty of Nursing and Midwifery, nonfaculty members, researchers of the research centers with master's degrees, PhD candidates, and residents. According to the previous studies (
7), considering the significance level of 0.05, and relative accuracy of 0.012, sample size was calculated at 100 for this cross-sectional study. Furthermore, SPSS (v.17, SPSS Inc., Chicago, IL, USA) was employed for statistical analysis, using descriptive statistics to calculate the frequencies and means of the individual barriers. One-way analysis of variance (ANOVA) and Kruskal-Wallis test were conducted to compare the barriers to research within and between the three main factors. P values below 0.05 were considered as statistically significant.