During the last two decades, the world economy has experienced a rapid growth in international Business. Despite the constant growth of world markets, there exist some worries regarding the effects of exchange rate volatility on business in general and on import and export in particular (
1). According to the economic theory, exchange rate movements cause changes in production, inflation, and interest rates by altering the relative prices of domestically and foreign produced goods and services (
2). The exchange rate pass-through affects the demand for real imports and adjustment of real net exports (
3). Real exchange rate volatility also is an important complication for investment planning, in particular for the investment in capacity in the exportable sectors. (
4). The issue of exchange policies and their effects on the macro variables of the economy is a controversial topic in the economy of all countries, especially the developing ones. Since in developing countries, the exchange rate is influenced by domestic and foreign shocks, it experiences greater fluctuations (
5). In every country, foreign business is known as the main factor in a way that the growth in this section is equivalent to the country's general economic growth; in addition, the exchange rate is considered as an influential factor in the foreign business volume (
6). Health costs have been considerably increasing throughout the recent decades and the world is dealing with this issue, yet (
7). Medicine section is one of the most significant and vital parts of a country's health system and medicine as a fundamental requirement and strategic good in each country possesses an undeniable value (
8,
9).
The medicine costs have experienced an increase in Iran, as well as some other countries, and these costs comprise about 30% of all health care costs and 50% of other costs in this realm (
10). The analysis of the pharmaceutical industry in Iran indicated that from 1997 to 2010, the medicine use and consumption had 28.38% increases each year. Moreover, the analysis of the domestic product and medicine imports indicated that Iran has experienced an annual growth of 9.3% and 3.42% in these realms, respectively (
11). According to the health ministry reports, domestic products have provided 96% of the country's medical requirements; however, the remaining 4% is very influential so that nearly 45% of the costs and values of the medicine market are allocated to this small portion. Meanwhile, the costs of producing domestic medicines are nearly 250 million dollars. In other words, 250 million dollars are allocated to 96% of the domestic products while 450 million dollars are spent on the remaining 4% of the medicines that are imported into the country (
12). Due to the considerable significance of medicine, the enormous costs allocated to it, the growth of medicine industry in our country, and the capability of our country to produce medicines, we should keep it in mind that a huge amount of money is sent out of the country for importing medicine or its primary materials. Therefore, the question raised in this regard is that how the exchange rate fluctuations will affect the import and export of medicines in the country.
After the demise of Bretton wood's system and implementation of floating exchange rate in the 1970s, it was proven that an increment in exchange rate fluctuations tends to create uncertainty, which can have a negative effect on commerce flows. Therefore, the effects of exchange rate fluctuations on business flows have been studied by the researchers and various lines of research were conducted in this regard. Although this issue is of considerable significance both inside and outside the Country, among the studies carried out in this realm, no specific research was conducted about the effects of exchange rate fluctuations on the medicine import and export. That is why some indirect studies accounting for this issue were drawn upon in order to provide an appropriate model. Employing the ARDL model, Alam (2012) estimated the demand function of Pakistan import and showed that there was a long-term relationship between import demand, real economic growth, real and effective exchange rate, and the fluctuations of the real exchange rate. These results indicated the negative effects between the fluctuations of the real exchange rate and Pakistan's import in a long-term period (
13).
Making use of the season data during 1980 - 2006, Hall studied the relationship between exchange rate fluctuations and business volume of 10 fledgling economic markets, as well as 11 developed countries, and reported that exchange rate fluctuations had a negative effect on the export of developed countries but it did not have any influence on the export of the fledgling countries. They inferred that the open financial markets (markets with a high degree of openness in trade) in the new countries, in comparison with the developed countries, may decrease their exports due to the fluctuations of the exchange rate (
14). Hericourt and Poncet conducted a study to investigate the effect of exchange rate volatility on the exporting performance and determine whether this impact depends on present fiscal constraints, which was carried out based on the experimental analysis of the export information of more than 100,000 Chinese exporters during 2000 to 2006. The results confirmed the prohibitive effects of exchange rate fluctuations on business and indicated that the decrease of export values has a considerable effect on the vulnerable financial companies. In addition, financial developments can adjust such negative effects, especially in exports (
15).
In another study carried out by Bahmani-Oskooee et al. on the effect of exchange rate fluctuations on goods commerce between the United States of America and Brazil, it was stated that fluctuations of exchange rate do not always influence the business negatively. Analyzing the cointegration, this study aimed at investigating the effects of exchange rate fluctuations on the bilateral export and import between the United States of America and Brazil during 1971-2010 and came to three conclusions. First, most industries are not influenced by such fluctuations in the long-term run. Second, sensitivity to this risk in the industry section is considerably different from other sections. And third, during the increase of fluctuations, producers having smaller shares in business would probably be affected much more than the producers with the main shares (
16).