Full Text
Full text is available in PDF
Familial Mediterranean Fever
Authors
+Corresponding Author: Department of Pediatrics, Nemazee Hospital, Shiraz, Iran., [email protected]. Tel: +98(711) 626-5024. Email: [email protected]
Published online:Apr 01, 2006
Article type:Review Article
How to Cite:Haghighat M. Familial Mediterranean Fever. Shiraz E-Med J. 2006;7(2):20368. doi:
Abstract
Familial Mediterranean Fever (FMF) or recurrent polyserositis is an inherited multisystem disease manifested by recurrent painful attacks affecting the abdomen, chest or joints, often accompanied by fever and sometimes a skin rash. FMF is a genetic condition, inherited in an autosomal recessive fashions. FMF could be described as a disorder of inappropriate inflammation of one or more of serusal membrane (serositis). The diagnosis of FMF is generally based on the clinical criteria although the direct analysis of MEFV gene is the only method to be certain of the disease. The goals of therapy are to reduce the morbidity and prevent complications of the disease, which is consists of taking colchicine, a neutrophil suppresisive agent. Since FMF is a genetic disease, it can be prevented only if the carriers of the defective gene are identified.
Copyright
© 2006, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
19
Oct
2024
Evaluation of Children with Familial Mediterranean Fever in South-Eastern Region of Türkiye
Alper Dogan,
Ayse Balat,
Beltinge Demircioglu Kilic,
Mehtap Akbalık Kara,
Mithat Buyukcelik
Dogan A, Balat A, Demircioglu Kilic B, Akbalık Kara M, Buyukcelik M. Evaluation of Children with Familial Mediterranean Fever in South-Eastern Region of Türkiye. Inn J Pediatr. 2025;35(1):e148367. doi: https://doi.org/10.5812/ijp-148367
8
Jun
2024
Genetic and Clinical Manifestations of Familial Mediterranean Fever in Children from the Central North of Iran
Shohreh Maleknejad,
Anahita Shabani,
Afshin Safaei Asl,
Aye Miremarati,
Parto Safaei-Asl,
Afagh Hassanzadeh Rad
Maleknejad S, Shabani A, Safaei Asl A, Miremarati A, Safaei-Asl P, et al. Genetic and Clinical Manifestations of Familial Mediterranean Fever in Children from the Central North of Iran. Inn J Pediatr. 2024;34(3):e146276. doi: https://doi.org/10.5812/ijp-146276
15
Apr
2015
The Association of Familial Mediterranean Fever and Polyarteritis Nodosa: A Case Report
Reza Shiari,
Hajar Sadat Ahadi,
Shirin Farivar,
Shirin Sayyahfar
Shiari R, Sadat Ahadi H, Farivar S, Sayyahfar S. The Association of Familial Mediterranean Fever and Polyarteritis Nodosa: A Case Report. Arch Pediatr Infect Dis. 2015;3(2):e17469. doi: https://doi.org/10.5812/pedinfect.17469
22
Jan
2024
Genetic and Clinical Study of Children with Familial Mediterranean Fever in Northeastern Iran
Abdolreza Malek,
Mohammadreza Abbaszadegan,
Niloofar Vakili,
Tina Zeraati,
Ehsan Ghayoor Karimiani,
Arian Sadrnabavi
Malek A, Abbaszadegan M, Vakili N, Zeraati T, Ghayoor Karimiani E, et al. Genetic and Clinical Study of Children with Familial Mediterranean Fever in Northeastern Iran. J Compr Ped. 2024;15(2):e140025. doi: https://doi.org/10.5812/jcp-140025
12
Jun
2017
MEFV Mutation Frequency in Pediatric Patients with Familial Mediterranean Fever and its Relationship with Clinical Phenotypes in Marmara Region of Turkey
Veysel Gok,
Ozgül Yigit,
Ozlem Bostan Gayret,
Sahin Hamilcikan
Gok V, Yigit O, Bostan Gayret O, Hamilcikan S. MEFV Mutation Frequency in Pediatric Patients with Familial Mediterranean Fever and its Relationship with Clinical Phenotypes in Marmara Region of Turkey. Inn J Pediatr. 2017;27(3):e10684. doi: https://doi.org/10.5812/ijp.10684
Cited by
- Scopus by DOI: 0
Last Update: 1 month ago
- Scopus by Title: 6
Last Update: 1 month ago
- Scopus by Title (Ref): 4
Last Update: 1 month ago
- CrossRef: 0
Last Update: 6 days ago
Comments
Number of Comments:0