Shiraz E-Medical Journal
The subject of adequacy in cervical smears has an essential role in the prevention of cervical cancer deaths. The predicament of establishing exactly what constitutes an adequate sample has received increasing attention in recent years. In this study, we tried to compare specimen adequacy and cytomorphological changes between conventional cervical and liquid based cytology Liqui-PREP TM.
A total of 170 asymptomatic women who undergo annual screening, were examined in cytopathology and gynecology departments (Al-Zahra Hospital of Isfahan University, Iran) during August 2008 to December 2008. Among which 153 cases, 93 cases: pre-menopause and 60 cases: post menopause women were subsequently selected. The conventional smears (CS) and Liquid-Based slides (LBS) using Liqui-PREP TM technique taken from each patient were evaluated carefully by a professional cytopathologist. The number of endocervical and transional zone's cells per slide, covering diagnostic squamous cells (%) and degenerated cells per high power microscopic field (HPF) were also counted. Other cytomorphological changes evaluated for postmenopausal women were included: number of eosinophilic pyknotic cells and spindled cells, basophilic globules (per HPF) and the presences of basophilic filaments (+/-).SPSS software was used for data analysis using indices of frequency percent, mean, and standard deviation for descriptive analysis
Mean of the patients' age was 42.28 which ranged from 20 to 67 years. The numbers of satisfactory cases with CS were 30 (31.9%) compared to 58 (62.4%) with the LBC (P
1. Liquid-PREP TM is a straight-forward cytological procedure, relying on classic cell handling procedures. 2. Cellular material is encapsulated in a matrix material that assures quantitative, robust adherence to the slide. 3. The number of cells transferred to the slide is controlled by the cytologist. 4. Liquid-PREP TM is not expensive
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© 0, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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