Mortality of Guillain-Barre syndrome in intensive care unite

M Yazdchi; H Mikaeli; MA Arami; safa najmi; L Mansorpoor

Zahedan Journal of Research in Medical Sciences

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Mortality of Guillain-Barre syndrome in intensive care unite

Author(s):

M Yazdchi¹,

H Mikaeli²,

MA Arami^3,*,

safa najmi⁴,

L Mansorpoor⁴

1Neurology Dept, Faculty of Medicine, Tabriz University of Medical Sciences and health services, Tabriz, Iran.

2Internal disease Dept, Faculty of Medicine, Tabriz University of Medical Sciences and health services, Tabriz, Iran.

3Neurology Dept, Faculty of Medicine, Kashan University of Medical Sciences and health services, Kashan, Iran

4Assistant of Neurology Department, Faculty of Medicine, Tabriz University of Medical Sciences and health services, Tabriz, Iran.

Zahedan Journal of Research in Medical Sciences:Vol. 7, issue 4; e94926

Published online:Dec 15, 2005

Article type:Research Article

Received:Dec 22, 2004

Accepted:Nov 25, 2005

How to Cite:M YazdchiH MikaeliMA Aramisafa najmiL MansorpoorMortality of Guillain-Barre syndrome in intensive care unite.Zahedan J Res Med Sci.7(4):e94926.

Abstract

Background: This study aims of determination of hospitalization period of cases with Guillain-
Barre syndrome (GBS) in Intensive cave unite (ICU), determination of ration of cases needing
mechanical ventilation and determination of effective factors on morbidity and mortality.
Methods and Materials: We evaluated retrospectively 80 medical records with GBS that admitted
to ICU ward Imam Khomeini Hospital between July 1999 to July 2004. Using chi-square, Exact
Fisher’s and t-tests, these cases were studied in terms of complication, mortality rate and death
causes in ICU.
Results: 55 patiets (68.7%) were male and 25 (31.2%) were female. Average of admission time to
ICU was 19.7 days. 27 patients (33.7%) had needed mechanical ventilation and 19 (23.7%)
infected by pneumonia. There was a statistically significant association between pneumonia and
mechanical ventilation (P<0.001). Mortality and morbidity were significantly high in association
with axonal type of syndrome (p<0.050). The most frequent complications were septicenimia and
autonomic dysfunction. Six patients (7%) ultimately died.
Conclusions: Considering the fact that the most common complication was septicemia and
autonomic dysfunction and there was a significant relationship between duration of hospitalization
and septicemia, enhancing the quality of intensive care could be effective in reducing mortality and
morbidity rates.

Keywords

Guillain-barre syndrome (GBS)

Intensive Care Unit (ICU)

Septicemia

Autonomic disorders

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