The abuse of methamphetamine has increased worldwide in recent years, and methamphetamine use is often associated with psychological disorders (
1). Therefore, researchers believe that self-regulation and self-control (and Affective control) can be affected by substance addicts’ behaviors. Self-regulation, defined as the psych’s efforts to control its internal states, processes and functions for the purpose of achieving a higher goal (
2). Self-regulation is also the capacity to override one’s thoughts, emotions, impulses, and automatic or habitual behaviors. People must constantly adapt and adjust their behavior to new environments and demands by self-regulating. Furthermore, self-regulation influences many of the major problems faced by people as individuals and society as a whole. For instance, poor self-regulation can be very difficult to abstain from drug and alcohol use after one has established a routine of regular use. Therefore, self-regulation can allow individuals to resist drug abuse, and thereby reduce various problems associated with such abuse (
3,
4). Also, it seems that self-regulation holds individual’s behavior under the control of social standards. Behaviors that are rewarded in the society, can lead to the self-regulation (
5). Therefore, when individuals use drugs, this rule is broken and drug use would reduce by addict's self-regulation (
3). On the other hand, in every society, self-control and affective control is important for getting along with others. A person who cannot control his or her thoughts, feelings, or behavior is more likely to lash out in anger when frustrated, handle conflicts less constructively, engage in antisocial behavior (
6); use drugs and commit substance-related problem behaviors presumably due to deficits in inhibitory control (
7,
8). Copeland and Sorensen found that methamphetamine users were more likely to have a psychiatric diagnosis. Mood disorders accounted for 71% of the diagnoses among methamphetamine users (
1). Sussman et al. have shown that behavioral self-control is inversely related to drug use, controlling for relatively unchangeable disorders of personality (
9). Glassman et al. found that self-control strategies are associated with alcohol consumption and self-regulation is also related to alcohol problems (
10). De wall et al. found that the capacity for self-control and self-regulation is a limited resource that operates like a strength or energy, and when this capacity is depleted, people are less successful in self-regulation and therefore they should be more likely to act aggressively if the aggressive impulse arises (
11). Vik showed that there is a positive relation between female methamphetamine abusers and psychiatric disorders (anxiety disorder, depression and interpersonal sensitivity), so that 53% of methamphetamine abusers had criteria for an affective disorder, and 46% of they had criteria for an anxiety disorder. (
12). Results of a study by Otten et al. showed that low levels of self-control are predictive of co-occurrence of cannabis use and depressive symptoms. Also, this study showed that individuals with low self-control may be incapable of inhibiting impulsivity which is a sign for substance use (
13). Study results of Cole et al. showed that affect, cognitive and behavior indicators of self-regulation were significant predictors of substance use disorder (
2).