The Importance of Diffusion Weighted Imaging in Breast MRI

Author(s):
Maryam NooriMaryam Noori1,*, Bahareh SiahlouBahareh Siahlou1, Hamidreza SalighehradHamidreza Salighehrad1, Anahita FathiAnahita Fathi1, Mohammad FathiMohammad Fathi1
1MD, Radiologist, Paytakht

IJ Radiology:Vol. 14, issue Special Issue; e47964
Published online:Apr 12, 2017
Article type:Abstract
Received:Dec 20, 2016
Accepted:Feb 07, 2017
How to Cite:Noori M, Siahlou B, Salighehrad H, Fathi A, Fathi M. The Importance of Diffusion Weighted Imaging in Breast MRI. I J Radiol. 2017;14(Special Issue):e47964. doi: https://doi.org/10.5812/iranjradiol.47964

Abstract

Objectives:

The aim of this study was to evaluate the value of diffusion weighted imaging in Diffusion weighted imaging in distinguishing between in benign and malignant breast lesion

Methods:

There were 37 female patients with 47 lesions. Sixty seven female subjectd (40 mean age ) ,age ranges 17-69 , with histopathologically proven breast lesions underwent DWI of breasts with a single shot echo planar imaging (EPI )sequence .the computed mean apparent diffusion cofficients (ADCs) of the breasts lesion and cell density were then correlated.

Results:

The ADC varied substantially between benign breast lesions ((1.52 0.26) 10 -3 mm2 / second). And malignant breast lesions ((0.94 0.21) 10 -3 mm2 / second) .The AUC with ROC analysis was 0.896 and the threshold for ADC was 1.17 10-3 mm2 /second with a sensitivity and specificity of 90% and 85%, respectively. The mean ADC of malignant breast lesions was statistically lower for benign lesions (P value less than 0.01)

Conclusions:

The ADC would be a effective parameter in distinguishing between malignant and benign breast lesions.

Full Text

Full text is available in PDF

Similar Articles

16
Jan
2016

Additional Value of Diffusion-Weighted Imaging to Evaluate Prognostic Factors of Breast Cancer: Correlation with the Apparent Diffusion Coefficient

Eun Kyung Park,
Kyu Ran Cho,
Bo Kyoung Seo,
Ok Hee Woo,
Sung Bum Cho,
Jeoung Won Bae

Park EK, Cho KR, Seo BK, Woo OH, Cho SB, et al. Additional Value of Diffusion-Weighted Imaging to Evaluate Prognostic Factors of Breast Cancer: Correlation with the Apparent Diffusion Coefficient. I J Radiol. 2016;13(1):e33133. doi: https://doi.org/10.5812/iranjradiol.33133

14
Feb
2026
Int J Cancer Manag

Evaluating Apparent Diffusion Coefficient (ADC) as a Non-invasive Imaging Biomarker for Breast Cancer Prognosis: Correlation with Histopathological and Molecular Biomarkers

Reza Kouhi,
Fariborz Faeghi,
Masoumeh Guity,
Hossein Jomleh,
Ali Shamooshaki

Kouhi R, Faeghi F, Guity M, Jomleh H, Shamooshaki A. Evaluating Apparent Diffusion Coefficient (ADC) as a Non-invasive Imaging Biomarker for Breast Cancer Prognosis: Correlation with Histopathological and Molecular Biomarkers. Int J Cancer Manag. 2026;19(1):e166882. doi: https://doi.org/10.5812/ijcm-166882

22
Jul
2015

Characterization of Soft Tissue Tumors by Diffusion-Weighted Imaging

Yeliz Pekcevik,
Mehmet Onur Kahya,
Ahmet Kaya

Pekcevik Y, Onur Kahya M, Kaya A. Characterization of Soft Tissue Tumors by Diffusion-Weighted Imaging. I J Radiol. 2015;12(3):e15478. doi: https://doi.org/10.5812/iranjradiol.15478v2

26
Jun
2019
63974

3 Tesla Apparent Diffusion Coefficient (ADC) Values of Thyroid Nodules: Prediction of Benignancy and Malignancy

Selen Bayraktaroglu,
Pınar Karakan Öztürk,
Naim Ceylan,
Özer Makay,
Gökhan İçöz,
Yeşim Ertan

Bayraktaroglu S, Öztürk PK, Ceylan N, Makay Ö, İçöz G, et al. 3 Tesla Apparent Diffusion Coefficient (ADC) Values of Thyroid Nodules: Prediction of Benignancy and Malignancy. I J Radiol. 2019;16(3):e63974. doi: https://doi.org/10.5812/iranjradiol.63974

5
May
2020
Iranian Journal of Radiology

Diagnostic Efficacy of Diffusion-Weighted Magnetic Resonance Imaging (DWI) in the Differentiation of Benign and Malignant Cervical Lymphadenopathies

Leila Aghaghazvini,
Bahman Rasuli,
Hashem Sharifian,
Fariba Hashemi,
Nasrin Yazdani,
Elahe Zaremehrjerdi

Aghaghazvini L, Rasuli B, Sharifian H, Hashemi F, Yazdani N, et al. Diagnostic Efficacy of Diffusion-Weighted Magnetic Resonance Imaging (DWI) in the Differentiation of Benign and Malignant Cervical Lymphadenopathies. I J Radiol. 2020;17(2):e91445. doi: https://doi.org/10.5812/iranjradiol.91445


Crossmark
Crossmark
Checking
Share on
Cited by
Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC 

Search Relations

Author(s):

Related Articles