Nursing is a frontline profession in health systems, characterized by heavy responsibility for direct patient care and constant exposure to suffering, pain, death, and interpersonal conflicts. International evidence indicates that healthcare workers, particularly nurses, are exposed to high levels of stress, burnout, anxiety, and depression, and their mental health has increasingly been recognized as a key public health priority (
1). During the COVID-19 pandemic, workload, fear of infection and transmission, shortages of protective equipment, and frequent exposure to death further exacerbated psychological distress among nurses and highlighted the urgent need for effective supportive interventions (
2).
In Iran, various studies have shown that nurses face considerable levels of occupational stress, emotional exhaustion, and mental health problems. Analytical research among Iranian nurses has demonstrated that organizational factors, high workload, rotating shifts, role conflict, and limited supportive resources are major determinants of job stress, burnout, and reduced job satisfaction (
3). Systematic reviews of spiritual health among Iranian nurses suggest that low spiritual health is associated with adverse psychological outcomes (
4). Moreover, a significant relationship has been reported between spiritual health and symptoms of stress, anxiety, and depression in various populations, including patients with chronic diseases (
5).
In recent decades, spirituality and in particular “spiritual health” has been recognized as an important dimension of health and an inner resource for hope, meaning, coherence, and adaptation in the face of life stressors (
4,
6). Existing evidence indicates that nurses’ spiritual health is associated with job satisfaction, professional commitment, quality of care, and lower intention to leave the profession (
6). Among healthcare workers, higher spiritual health has also been linked with lower levels of stress, anxiety, and depression (
5).
Beyond measuring spirituality, educational interventions based on “spiritual intelligence” and “spiritual skills” have attracted increasing attention. These interventions seek to transform abstract spiritual concepts into teachable and practicable skills in daily life, such as meaning-making, trust in God (tawakkul), gratitude, patience, forgiveness, altruism, and spiritual self-awareness (
7-
9). Reviews indicate that structured spiritual skills training packages can enhance spiritual health, improve coping, and reduce psychological problems in different populations (
8,
9).
In nursing, several interventions have been implemented to strengthen spirituality and spiritual skills. Some studies report that spiritual intelligence training improves nurses’ communication skills, enhances care quality, and reduces job stress (
10,
11). Other research demonstrates that spiritually based interventions and spiritual group therapy among psychiatric nurses improve psychological well-being, increase job satisfaction, and reduce anxiety, depression, and job stress (
12-
15). Spiritual self-care education has also been shown to increase resilience and reduce psychological strain among nurses working in intensive care units dedicated to COVID-19 patients (
16), and virtual spiritual self-care training has reduced COVID-related anxiety in final-year nursing students (
17).
From a theoretical perspective, the mechanisms by which spiritual interventions exert their effects can be explained within the frameworks of “stress appraisal and coping” and “spiritual coping.” In Folkman’s model, the individual’s primary appraisal of a stressor and secondary appraisal of available coping resources play a central role in the experience of stress and its outcomes (
18). Spirituality and spiritual skills can provide a meaningful framework for interpreting stressful events, strengthen belief in meaning and purpose in life, foster a sense of connection with a transcendent source, and increase hope, thereby modifying cognitive appraisal of difficult situations (
19). Emphasis on spiritual values such as altruism, gratitude, forgiveness, and patience may also promote more positive interpersonal relationships, greater social support, and a sense of internal efficiency, which are considered protective factors against stress and burnout (
3,
6).
Despite growing research on spirituality and nursing, interventional evidence regarding the effects of structured spiritual skills training on stress, anxiety, and depression among nurses in psychiatric hospitals, especially within the cultural and religious context of Iran, remains limited. Although some domestic studies have examined spiritual interventions and their impact on nurses’ mental health and job-related outcomes (
12-
15), few quasi-experimental studies with two-group designs and standardized psychometric instruments have been conducted in psychiatric settings.