IJ Radiology
Malignant mesothelioma and metastatic adenocarcinoma are the two most common pleural malignancies. They have similar imaging findings but different prognosis and treatment. CT scan is the modality of choice for their diagnosis.
In this study, details of chest CT findings in these two conditions were assessed to find out if there are any imaging clues for early differentiation.
Chest CT scan of 113 patients [metastatic adenocarcinoma: 58 (52%) and malignant mesothelioma: 55 (48%)] were retrospectively reviewed by two radiologists with consensus at Masih Daneshvari University Hospital Medical Center, Tehran, Iran between 2005 to 2010. Patients were assessed for 35 CT variables and smoking and occupational history.
Malignant mesothelioma needs to be distinguished from metastatic adenocarcinoma. These pleural tumors have different treatments and prognoses. CT scan is a primary and good imaging technique that can be used in order to differentiate these two entities. Albeit non-identical, CT appearances of malignant mesotheliomas and metastatic adenocarcinomas have similar features. Using a check list containing the mentioned diagnostic CT features can be helpful in differentiation between these two diseases.
© 2014, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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