| T1 | Premkumar et al. (1), 2018, India | 1st, 2nd, 3rd, 4th year, and interns (n = 452); Mixed method study | Multiple methods: Student-led seminars, topic-specific presentations, tutorials, and providing students with lecture; topics beforehand | Motivational, time management, identifying your own skill and abilities | Useful only if assessment-driven, insufficient time, difficult for ‘spoon-fed’ students, distractions due to modern technology, result-oriented approach, difficulty in accepting a novel method | SDL |
| T2 | Hill et al. (12), 2020, USA | 1st year (n = 131); survey and thematic analysis of open-ended questions | Team-based learning | Enjoying the course helps critical thinking, time management, helps skill development, knowledge application, | Not mentioned. | SDL |
| T3 | Peine et al. (13), 2016, Germany | 3rd year (n = 244); before and after study | Mixed method: Lectures, seminars, e-learning, | helps active recall, teamwork | Complex subjects cannot be fully taught in classrooms, accustomed to concentrated individual work, limitations of precise instruction of the teachers | SDL |
| T4 | Abraham et al. (14), 2017, India | 1st year (n = 120); descriptive study | Technology-enhanced learning experience, Pecha Kucha PK talks (type of group discussion) | Improves presentation skills, collaborative learning skills, teamwork | Demands a lot of effort and time from both faculty and students | SDL |
| T5 | Bobby et al. (15), 2018, India | 1st year biochemistry; before and after study | Open-book test versus self-study | Better retention, critical thinking, helping the focused learning process | Vast knowledge, limited time frame | SDL |
| T6 | Kershaw et al. (16), 2017, UAE | 2nd year (n = 206); interventional study | Project-based learning | Promotes literature searching, writing skills, presentation skills, and teamwork | PBL is a novel method, requires planning and research skills, problems with team participation | SDL |
| T7 | Pai et al. (17), 2014, India | 1st year (n = 237); cross-sectional study | Case-based scenarios | Better knowledge acquisition | Role is reduced in first year settings | SDL |
| T8 | Patra et al. (18), 2020 India | 1st year (n = 160); cross-sectional mixed method | Discussions on case based scenarios, flipped classrooms, student led seminars, movie screening, panel discussions, role plays | Enjoyable, an innovative way, motivation, teamwork, confidence-building | Few active members in group, long duration, too much feedback | SDL |
| T9 | Gune (19), 2018, India | 1st year (n = 140); before and after study | Brain storming and presentation sessions | Improving understanding, promoting curiosity, generating new ideas, | Time consuming | SDL |
| T10 | Zheng and Zhang (20), 2020, Midwestern United States | 1st and 2nd year (n = 146); qualitative study | Flipped classrooms | Beneficial to stay engaged, obtaining better explanations, and asking better questions, lowering anxiety | Too little lecture-based teaching, too much independent learning, the large volume of information available, difficult to “staying organized”, time management, difficult to obtain help | SRL |
| T11 | Cleary and Sandars (21), 2011, UK | 3rd year (n = 7); qualitative case description study | Venipuncture on a simulation mannequin arm | Self-regulatory processes | To judge poor performance is problematic, particularly for low achieving or at-risk students, negative effects, such as avoidance and anxiety | SRL |
| T12 | Demiroren et al. (22), 2020, Turkey | 3rd year (n = 257); cross-sectional study | PBL | SRL skills to understand their own ability | Not mentioned | SRL |
| T13 | Demiroren et al. (23), 2016, Turkey | 2nd (n = 286) and 3rd (n = 275) year; cross-sectional study | PBL | Motivation, planning and goal setting, strategy use and assessment | Difficulties in taking learning responsibility and teamwork, individual counseling and support, lack of group interaction, problem-solving | SRL |
| T14 | Topale (24), 2016, Grenada | 1st and 2nd year (n = 281); electronic survey | Lecture recordings | Controling over time, critical thinking, skills gaining personal time, increasing study time | Hinders participation of medical students in live lectures, non-interactive, technical assistance is further required | SRL |
| T15 | Vavasseur et al. (25), 2020, USA | 4th year (n = 353); single site prospective study | Flipped classrooms and short videos | Enjoy, improving flexibility, allowing improvement in performance, satisfaction and engagement, improving knowledge | Not mentioned | SRL |
| T16 | Safir et al.(26), 2013 Netherlands | 1st and 2nd year (n = 38); before and after study | Instructional videos | Simple procedure can be mastered | Complex interaction of task difficulty and training conditions required for optimal learning | SRL |