Development and Evaluation of Talisapatradi and Vyoshadi Choorna Lozenges: An Ayurvedic Traditional Formulation

Manas-Ranjan Sahoo; Umashankar Marakanam Srinivasan; Ramesh Varier

doi:10.4103/jrptps.JRPTPS_80_21

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https://doi.org/10.4103/jrptps.JRPTPS_80_21

Development and Evaluation of Talisapatradi and Vyoshadi Choorna Lozenges: An Ayurvedic Traditional Formulation

Author(s):

Manas-Ranjan Sahoo¹,

Umashankar Marakanam Srinivasan

^1,*,

Ramesh Varier²

1Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India

2AVN Ayurveda Formulation Pvt Ltd, Madurai, Tamil Nadu 600034, India

Journal of Reports in Pharmaceutical Sciences:Vol. 11, issue 1; 110-7

Published online:Jun 29, 2022

Article type:Research Article

Received:Jun 17, 2021

Accepted:Apr 12, 2022

How to Cite:Manas-Ranjan SahooUmashankar Marakanam SrinivasanRamesh VarierDevelopment and Evaluation of Talisapatradi and Vyoshadi Choorna Lozenges: An Ayurvedic Traditional Formulation.J Rep Pharm Sci.11(1):e146225.https://doi.org/10.4103/jrptps.JRPTPS_80_21.

Abstract

In Ayurveda, Talisapatradi choorna (TPC) and Vyoshadi choorna (VSC) are commonly used medicines for
cough, cold, asthma, and rhinitis. These symptoms are due to upper respiratory infections of predominantly
of viral origin. Currently, there are no effective medicines except indiscriminate uses of antibiotics, local
anesthetics, and pain killers. The conventional formulation of TPC and VSC is difficult to administer
so an easy manufacturing lozenge formulation was developed. The phytochemical analysis was done
by preliminary thin layer chromatography (TLC) derivatization studies. High-performance thin layer
chromatography (HPTLC) analysis confirmed the presence of herbal actives in the lozenge formulations.
The TLC analysis results showed that TPC and VSC contain phytochemicals of flavonoids, steroids and
phytosterols, and alkaloids family. The herbal actives were found to be stable in the final formulation
without any interference with the excipients used in the formulation. The lozenges formulated from TPC
and VSC are found to be promising alternatives to traditional form for the traditional Ayurvedic preparation.
Compatibility study was done using Fourier transform infrared spectroscopy and HPTLC study.

Keywords

Characterization

formulation developmen

heavy metals

HPTLC analysis

lozenges

physicochemical analysis

Talisapatradi choorna

Vyoshadi choorna

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Author(s):

Manas-Ranjan Sahoo:[PubMed][Scholar]
Umashankar Marakanam Srinivasan:[PubMed][Scholar]
Ramesh Varier:[PubMed][Scholar]