The Effect of Anthraquinones Fractions from Morinda Citrifolia Leaves against Pathogenic Bacteria with Antioxidant Activities

Abdul Mushin M. Shami

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The Effect of Anthraquinones Fractions from Morinda Citrifolia Leaves against Pathogenic Bacteria with Antioxidant Activities

Author(s):

Abdul Mushin M. Shami^1,*

1Department of Biotechnology, Institute of Genetics Engineering and Biotechnology, University of Baghdad, Baghdad, Iraq

Journal of Reports in Pharmaceutical Sciences:Vol. 7, issue 3; 231-239

Published online:May 29, 2018

Article type:Research Article

Received:Mar 08, 2018

Accepted:May 12, 2018

How to Cite:Abdul Mushin M. ShamiThe Effect of Anthraquinones Fractions from Morinda Citrifolia Leaves against Pathogenic Bacteria with Antioxidant Activities.J Rep Pharm Sci.7(3):e147490.

Abstract

The objectives of this study were to evaluate the antibacterial and antioxidant activities from anthraquinones fractions from leaves of Morinda citrifolia. Anthraquinones fraction from the leaves of M. citrifolia exhibited significant inhibition against the test of bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and Helicobacter pylori (H. pylori). Anthraquinones fraction of the leaves have antioxidant activities. LC-MS analysis of anthraquinones of the M. citrifolia leaves identified specific compounds in these fractions. Scanning electron microscope results of these substances showed significant morphological changes of cell wall membrane and destruction of bacterial cell. It could be concluded that the anthraquinones of the part of this plant had a good antibacterial and antioxidant effects. The results suggest the anthraquinones of the part of this plant can be a new source of antimicrobials against pathogenic bacteria and antioxidant source.

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