Two Iridoid Structures from Eremostachys macrophylla Montbr. & Auch. Rhizomes

authors:

avatar Abbas Delazar 1 , avatar Solmaz Asnaashari 2 , *

Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

how to cite: Delazar A, Asnaashari S. Two Iridoid Structures from Eremostachys macrophylla Montbr. & Auch. Rhizomes. J Rep Pharm Sci. 2018;7(2):e147590. 

Abstract

The air- dried and ground rhizomes of Eremostachys macrophylla Montbr. & Auch., as wild-growing plant in East Azerbaijan province, of Iran, were extracted with n-hexane, dichloromethane (DCM) and methanol (MeOH) solvents using a soxhlet apparatus. The 10% MeOH in water Sep-Pak fractions of the MeOH extract was subjected to preparative reversedphase high performance liquid chromatography (RP-HPLC) and the isolated pure compounds were identified by one- dimensional nuclear magnetic resonance (1D-NMR) spectroscopic technique. The obtained results showed the presence of two pure components, 6- Hydroxyl Loganin, (1) and Lamalbide (2) with iridoid structures. The results demonstrated the rhizomes of E. macrophylla could be a good source of iridoids.