Two Iridoid Structures from Eremostachys macrophylla Montbr. & Auch. Rhizomes

authors:

avatar Abbas Delazar 1 , avatar Solmaz Asnaashari 2 , *

Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

How To Cite Delazar A, Asnaashari S. Two Iridoid Structures from Eremostachys macrophylla Montbr. & Auch. Rhizomes. J Rep Pharm Sci. 2018;7(2):e147590. 

Abstract

The air- dried and ground rhizomes of Eremostachys macrophylla Montbr. & Auch., as wild-growing plant in East Azerbaijan province, of Iran, were extracted with n-hexane, dichloromethane (DCM) and methanol (MeOH) solvents using a soxhlet apparatus. The 10% MeOH in water Sep-Pak fractions of the MeOH extract was subjected to preparative reversedphase high performance liquid chromatography (RP-HPLC) and the isolated pure compounds were identified by one- dimensional nuclear magnetic resonance (1D-NMR) spectroscopic technique. The obtained results showed the presence of two pure components, 6- Hydroxyl Loganin, (1) and Lamalbide (2) with iridoid structures. The results demonstrated the rhizomes of E. macrophylla could be a good source of iridoids.