Dynamics of mammalian sperm heads

Preface

Mammalian sperm possess a complex structure, with significant correlations between sperm structure and functionality being explored extensively. Numerous studies have documented sequential changes in sperm components from their production during spermatogenesis to fertilization and embryo formation. Advanced microscopy techniques, such as light and electron microscopy, alongside immunohistochemistry methods utilizing specific probes like antibodies against sperm components, have significantly contributed to this research.

In addition, genetic manipulation techniques and studies on molecular interactions controlling sperm structure and composition have progressed. Animal models with induced genetic mutations have revealed abnormal morphology and functionality associated with male infertility. In humans, male infertility can arise from diverse factors, including environmental conditions, mutagenic agents, and diet-related genotoxins. These factors not only impact the development of germ cells during spermatogenesis but also affect the functionality of mature sperm, ultimately disrupting fertilization and embryonic development.

This book delves into the dynamics of mammalian sperm, focusing on events that occur in the sperm head from its formation during spermatogenesis to oocyte activation. It examines cellular processes, their successful outcomes, and their failures, offering a comparative analysis of animal models, human infertility cases, and natural fertilization processes.

Chapter Highlights

• Chapter 1: Dynamics of the Mammalian Sperm Head (Page 3)
• Chapter 2: Structures and Activities of the Sperm Head (Page 13)
  • Cytoplasmic Layers
  • Acrosomal and Subacrosomal Cytoplasmic Layers
  • Post-Acrosomal Cytoplasmic Layers
  • Membrane Systems
• Chapter 3: Sperm Head Structure and Influencing Factors (Page 23)
  • Cellular Interactions
  • Stem Cell and Related Factors
  • Intercellular Bridges
• Chapter 4: Post-Testicular Modifications and Maturation Events in the Sperm Head (Page 39)
• Chapter 5: Dynamics of the Acrosome (Page 45)
• Chapter 6: Dynamics of the Perinuclear Theca (Page 61)
• Chapter 7: Dynamics of the Sperm Nucleus (Page 65)
• Chapter 8: Membrane System Dynamics (Page 77)
• Chapter 9: Oocyte Activation Dynamics (Page 103)
• Chapter 10: Sperm Head Behavior in Natural Fertilization, IVF, and ICSI (Page 113)
• Chapter 11: Conclusion (Page 115)

Book Details

• Author: Toshimori, Kiyotaka
• Translators: Hamid Kahram, Navid Dadash Por, Bahram Afrasiyabi
• Publisher: Pouyan Kowsar Health Publishing Company; 1st Edition (April 27, 2022)
• Publication Date: April 27, 2022
• Print Length: 142 Pages
• Language: Persian
• ISBN: 978-622-94614-5-7
• Sponsored by: Salamat Pooyan

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• Link to Table of Contents (Persian)