Logo
homeHome

IJ Radiology

An Innovative Journal in the Field of Radiology

homeHome
helpInstructions
format_list_bulletedAPC
Authors GuideSubmit Manuscript

Outlines

https://doi.org/10.5812/iranjradiol.48282

Application of PET/CT in Oncologic Imaging

Author(s):
Sohaila YazdaniSohaila Yazdani1,*, Homayon FallahHomayon Fallah1, Fahimeh RezaieFahimeh Rezaie1
1Kermanshah University of Medical Science, Kermanshah, Iran
IJ Radiology:Vol. 14, issue Special Issue; e48282
Published online:Apr 12, 2017
Article type:Abstract
Received:Dec 20, 2016
Accepted:Feb 07, 2017
How to Cite:Yazdani S, Fallah H, Rezaie F. Application of PET/CT in Oncologic Imaging. I J Radiol. 2017;14(Special Issue):e48282. doi: https://doi.org/10.5812/iranjradiol.48282

Abstract

Background:

There are many challenges in oncologic imaging including: more accurate staging, determine site with highest probability of tumor existence for biopsy, especially for brain tumors because of the sensitive anatomical position, determine the exact location of the tumor for radiotherapy treatment planning and etc. Positron emission tomography (PET) is imaging modality which provides some special functional information. The basis of the PET system is detection of tow photons which are generated by positron/electron encounter which occurs directly after positron emission by radionuclide. However, it is powerless in providing anatomical information. Computed tomography (CT) generates three dimensional reconstructions of patients anatomy based on differences in X-ray attenuation. Combination of PET and CT is able to provide anatomical and physiological information of patients synchronizes.

Objectives:

In this paper, we evaluate application of PET/CT for improve oncologic imaging.

Methods:

The papers were searched in PubMed and Scopus databases with the relevant key words including, PET/CT, Oncologic Imaging and Cancer staging.

Results:

The most relevant biomarker for PET is 8F- FDG (F-18 Fluorodeoxyglucose), which is incorporated into malignant cells by glucose transporters which are over expressed by cancer cells. CT is the common imaging modality in diagnosis the cancers. It is due to its speed, high special resolution and relative cost-effectiveness. The combination of these two modalities in one system produced PET/CT system which is more accurate than these two imaging modalities separately and enhances the sensitivity and specificity of diagnosis. For example in a study which used PET/CT for differentiation between the malignant and benign disease Presacral, sensitivity, specificity, the positive predictive value and the negative predictive value are 100%, 96%, 88% and 100% respectively. In another study, which was done for preradiotherapy staging of head-and-neck SCCs, it was shown that FDG-PET/CT detected 17 of 17 heminecks and 26 of 27 nodal zones histologically positive by dissection (100% and 96% sensitivity, respectively).

Conclusions:

PET/CT can provide diagnosis and more accurate staging, location of tumor with its capability in providing the anatomical and physiological information synchronizes. Therefore PET/CT plays an important role in oncology.

Keywords
PET/CT
Oncologic Imaging and Cancer Staging

Full Text

Full text is available in PDF

Similar Articles

1
Mar
2014

Role of Positron Emission Tomography–Computed Tomography in Pulmonary Neoplasms

Mehrdad Bakhshayeshkaram

Bakhshayeshkaram M. Role of Positron Emission Tomography–Computed Tomography in Pulmonary Neoplasms. I J Radiol. 2014;11(30th Iranian Congress of Radiology):e93645. doi: https://doi.org/10.5812/iranjradiol.21330

12
Apr
2017

The Role of 18F FDG PET/CT in Clinical Management of Breast Cancer; Additional Value Over Conventional Imaging Modalities

Mehrdad Bakhshayeshkaram,
Farahnaz Aghahosseini,
Abtin Doroudinia

Bakhshayeshkaram M, Aghahosseini F, Doroudinia A. The Role of 18F FDG PET/CT in Clinical Management of Breast Cancer; Additional Value Over Conventional Imaging Modalities. I J Radiol. 2017;14(Special Issue):e47975. doi: https://doi.org/10.5812/iranjradiol.47975

13
Apr
2017

Role of FDG PET/CT Scan in Head and Neck Cancer Patients

Mehrdad Bakhshayesh Karam,
Abtin Doroudinia,
Farahnaz Aghahosseini,
Fatemeh Kaghazchi,
Payam Mehrian

Bakhshayesh Karam M, Doroudinia A, Aghahosseini F, Kaghazchi F, Mehrian P. Role of FDG PET/CT Scan in Head and Neck Cancer Patients. I J Radiol. 2017;14(Special Issue):e93673. doi: https://doi.org/10.5812/iranjradiol.47980

24
Sep
2012

FDG PET/CT in Prostate Cancer: A Valuable Method to Detect the Primary and Metastatic Tumor Sites and to Monitor Cancer Response to Hormonal Therapy

Alexander Hinev,
Borislav Chaushev,
Aneliya Klisarova

Hinev A, Chaushev B, Klisarova A. FDG PET/CT in Prostate Cancer: A Valuable Method to Detect the Primary and Metastatic Tumor Sites and to Monitor Cancer Response to Hormonal Therapy. Nephro-Urol Mon. 2012;4(4):644-645. doi: https://doi.org/10.5812/numonthly.4539

10
Jan
2016

Role of 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Evaluation of Cytologically Indeterminate Thyroid Nodules

Gulgun Buyukdereli,
Yasemin Aktar,
Ertan Kara,
Aysun Uguz,
Husnu Sonmez

Buyukdereli G, Aktar Y, Kara E, Uguz A, Sonmez H. Role of 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Evaluation of Cytologically Indeterminate Thyroid Nodules. I J Radiol. 2016;13(1):e21186. doi: https://doi.org/10.5812/iranjradiol.21186

Import into EndNoteImport into BibTex
Crossmark
Crossmark
Checking
Share on
Comments
Number of Comments:0
Cited by
Metrics
Licensing and reuse information

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC 

Search Relations

Author(s):

Related Articles

Related Article in PubMed

Related Article in Google Scholar

Create Citation Alert via Google Reader