Outline
Evaluation of the Efficacy of Dexamethasone Versus Magnesium Sulfate in Prevention of Postspinal Shivering: A Prospective, Randomized, Double-Blind Study
Authors
Abstract
Background: Postspinal shivering represents one of the distressing complications of regional anesthesia. This study evaluated the efficacy of dexamethasone and magnesium sulfate to prevent postspinal shivering (PSAS) in lower abdominal and lower limb surgeries. Materials and Methods: Hundred forty-seven patients undergoing elective abdominal and lower limb surgery under spinal anesthesia received either 100 mL isotonic saline (group C), 8 mg in 100 mL isotonic saline (group D), or magnesium sulfate 30 mg/kg in 100 mL isotonic saline (Group M). Results: The incidence of clinically significant shivering was highly significantly less in group D and group M compared to group C (p=0.001), however, there was no statistically significant difference between group D and group M (p=0.052). The onset of shivering was significantly lower in the C group compared to the D and M groups with statistically significant differences between the D and M groups (p=0.001). Conclusion: Dexamethasone and magnesium sulfate were effective in the prevention of PSAS in patients undergoing lower abdominal and lower limb surgeries under spinal anesthesia. However, magnesium sulfate is better than dexamethasone as it is accompanied by less incidence of shivering, and its sedative effect decreases the stress of the surgery.
References
- 1.References are in the PDF file of the article.
Copyright
© 2023, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
The Effect of Intravenous Dexmedetomidine During Surgery in the Prevention of Shivering After General Anesthesia in Patients Undergoing Spinal Surgery: A Randomized Clinical Trial
Shokri M, Bakhtiari Z, Kargar B, Hajialigol A. The Effect of Intravenous Dexmedetomidine During Surgery in the Prevention of Shivering After General Anesthesia in Patients Undergoing Spinal Surgery: A Randomized Clinical Trial. Anesth Pain Med. 2025;15(2):e159077. doi: https://doi.org/10.5812/aapm-159077
Is Dexmedetomidine Effective on Postoperative Shivering in Patients Undergoing General Anesthesia for an Appendectomy? A Double–Blind, Randomized Clinical Trial
Ahsan B, Majedi MA, Sin Darreh S, Masaeli M. Is Dexmedetomidine Effective on Postoperative Shivering in Patients Undergoing General Anesthesia for an Appendectomy? A Double–Blind, Randomized Clinical Trial. Interv Pain Med Neuromod. 2023;3(1):e140583. doi: https://doi.org/10.5812/ipmn-140583
Does Route Matter? A Randomized Double-Blind Trial Comparing Intravenous and Intrathecal Dexmedetomidine for Prevention of Post-spinal Shivering in Cesarean Delivery
Masaeli M, Habibzadeh MR, Sindarreh S, Faraji T, Kalantari Sarcheshmeh MS. Does Route Matter? A Randomized Double-Blind Trial Comparing Intravenous and Intrathecal Dexmedetomidine for Prevention of Post-spinal Shivering in Cesarean Delivery. Shiraz E-Med J. 2026;27(3):e165449. doi: https://doi.org/10.5812/semj-165449
A Comparative Study Between the Efficacy of Magnesium Sulphate and Dexmedetomidine for Cough Suppression During Anesthetic Emergence in Smokers Undergoing Elective Abdominal Surgery: A Randomized Double-Blind Controlled Trial
Mohamed Talaat S, Shahat Mohamed M, Abdelghani Bassiony M, Mohamed Abdelaziz N, Ghoneim MA. A Comparative Study Between the Efficacy of Magnesium Sulphate and Dexmedetomidine for Cough Suppression During Anesthetic Emergence in Smokers Undergoing Elective Abdominal Surgery: A Randomized Double-Blind Controlled Trial. J Cell Mol Anesth. 2025;10(3):e164623. doi: https://doi.org/10.5812/jcma-164623
Magnesium Can Decrease Postoperative Physiological Ileus and Postoperative Pain in Major non Laparoscopic Gastrointestinal Surgeries: A Randomized Controlled Trial
Shariat Moharari R, Motalebi M, Najafi A, Zamani MM, Imani F, et al. Magnesium Can Decrease Postoperative Physiological Ileus and Postoperative Pain in Major non Laparoscopic Gastrointestinal Surgeries: A Randomized Controlled Trial. Anesth Pain Med. 2014;4(1):e12750. doi: https://doi.org/10.5812/aapm.12750
- Scopus by DOI: 0
Last Update: 1 month ago
- Scopus by Title: 0
Last Update: 1 month ago
- Scopus by Title (Ref): 0
Last Update: 1 month ago
- CrossRef: 0
Last Update: 2 hours ago