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Iranian Journal of Pharmaceutical Research

e-ISSN 1726-6890
p-ISSN 1735-0328
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Volume 19, Issue 1

40 articles2020-01-31Vol. 19Issue 1XML
31
Jan
2020
Letter to Editor_imported

Thalidomide against Coronavirus Disease 2019 (COVID-19): A Medicine with a Thousand Faces

Farzaneh Dastan,
Payam Tabarsi*,
Majid Marjani,
Afshin Moniri,
Seyed Mohammad Reza Hashemian,
Maria Tavakoli-Ardakani
,et al.
PDFFinal Published
31
Jan
2020
CB2 Agonist (AM1241) Improving Effect on Ovalbumin-Induced Asthma in Rats
Original Article

CB2 Agonist (AM1241) Improving Effect on Ovalbumin-Induced Asthma in Rats

Ali Parlar*,
Seyfullah Oktay Arslan
PDFFinal Published
31
Jan
2020
Determination of Mirtazapine and Desmethyl Mirtazapine in Human Plasma by a New Validated HPLC Ultraviolet Method with a Simple and Reliable Extraction Method: Application to Therapeutic Drug Monitoring Study by 62 Real Patient Plasma
Original Article

Determination of Mirtazapine and Desmethyl Mirtazapine in Human Plasma by a New Validated HPLC Ultraviolet Method with a Simple and Reliable Extraction Method: Application to Therapeutic Drug Monitoring Study by 62 Real Patient Plasma

Emrah Dural*,
Nilay Sedes Baskak,
Hatice Özcan,
Yağmur Kır,
Bora Başkak,
Halil Sinan Süzen
PDFFinal Published
31
Jan
2020
A Fourteen-day Experience with Coronavirus Disease 2019 (COVID-19) Induced Acute Respiratory Distress Syndrome (ARDS): An Iranian Treatment Protocol
Original Article

A Fourteen-day Experience with Coronavirus Disease 2019 (COVID-19) Induced Acute Respiratory Distress Syndrome (ARDS): An Iranian Treatment Protocol

Hamidreza Jamaati,
Farzaneh Dastan*,
Payam Tabarsi,
Majid Marjani,
Ali Saffaei,
Seyed MohammadReza Hashemian*
PDFFinal Published
31
Jan
2020
Silencing of Nucleostemin by siRNA Induces Apoptosis in MCF-7 and MDA-MB-468 Cell Lines
Original Article

Silencing of Nucleostemin by siRNA Induces Apoptosis in MCF-7 and MDA-MB-468 Cell Lines

Mahdiyeh Moudi,
Ramin Saravani*,
Saman Sargazi*
PDFFinal Published
31
Jan
2020
Raise up of Scopolamine in Hairy Roots Via Agrobacterium rhizogenes ATCC15834 as Compared with Untransformed Roots in Atropa komarovii
Original Article

Raise up of Scopolamine in Hairy Roots Via Agrobacterium rhizogenes ATCC15834 as Compared with Untransformed Roots in Atropa komarovii

Ofelia Banihashemi,
Ramazan-Ali Khavari-Nejad*,
Narguess Yassa,
Farzaneh Najafi
PDFFinal Published
31
Jan
2020
Early Graft Function in Deceased Donor Renal Recipients: Role of N-Acetylcysteine
Original Article

Early Graft Function in Deceased Donor Renal Recipients: Role of N-Acetylcysteine

Atieh Modarresi,
Mohsen Nafar,
Zahra Sahraei*,
Jamshid Salamzadeh,
Shadi Ziaie
PDFFinal Published
1
Jun
2019
Utilization Evaluation of Human Papilloma Virus Vaccine (GARDASIL®) in Iran; A Cross-Sectional Study.
Research Article

Utilization Evaluation of Human Papilloma Virus Vaccine (GARDASIL®) in Iran; A Cross-Sectional Study.

Fateme Mohammadpour,
Ava Mansouri*,
Molouk Hadjibabaie
PDFFinal Published
31
Jan
2020
Phytochemical Study of Tanacetum Sonbolii Aerial Parts and the Antiprotozoal Activity of its Components
Original Article

Phytochemical Study of Tanacetum Sonbolii Aerial Parts and the Antiprotozoal Activity of its Components

Sahar Mofidi Tabatabaei,
Mahdi Moridi Farimani*,
Samad Nejad-Ebrahimi,
Peyman Salehi
PDFFinal Published
31
Jan
2020
3-Hydroxypyrimidine-2, 4-dione Derivatives as HIV Reverse Transcriptase-Associated RNase H Inhibitors: QSAR Analysis and Molecular Docking Studies
Original Article

3-Hydroxypyrimidine-2, 4-dione Derivatives as HIV Reverse Transcriptase-Associated RNase H Inhibitors: QSAR Analysis and Molecular Docking Studies

Azar Mostoufi,
Narges Chamkouri,
Samaneh Kordrostami,
Elham Alghasibabaahmadi,
Ayyub Mojaddami*
PDFFinal Published
31
Jan
2020
Therapeutic Effects of Oleuropein in Improving Seizure, Oxidative Stress and Cognitive Disorder in Pentylenetetrazole Kindling Model of Epilepsy in Mice
Original Article

Therapeutic Effects of Oleuropein in Improving Seizure, Oxidative Stress and Cognitive Disorder in Pentylenetetrazole Kindling Model of Epilepsy in Mice

Samira Asgharzade,
Zahra Rabiei,
Sana Rabiei,
Elham Bijad,
Mahmoud Rafieian-Kopaei*
PDFFinal Published
31
Jan
2020
Evaluation of Neuroprtective Effects of L-Carnitine and Fat Emulsion in the CVA Patients: A Prospective, Randomized, Double Blind, Clinical Trial
Original Article

Evaluation of Neuroprtective Effects of L-Carnitine and Fat Emulsion in the CVA Patients: A Prospective, Randomized, Double Blind, Clinical Trial

Kaveh Kazemian,
Shahram Ala*,
Mojtaba Mojtahedzadeh,
Mahmoud Abedini,
Abbas Alipour,
Saeid Abediankenari
,et al.
PDFFinal Published
31
Jan
2020
Synthesis of Flower-like Nickel Hydroxide Nanosheets and Application in Electrochemical Determination of Famotidine
Original Article

Synthesis of Flower-like Nickel Hydroxide Nanosheets and Application in Electrochemical Determination of Famotidine

Rezvan Dehdari Vais,
Hossein Yadegari,
Hossein Heli*
PDFFinal Published
31
Jan
2020
Design and Evaluation of Losartan Transdermal Patch by Using Solid Microneedles as A Physical Permeation Enhancer
Original Article

Design and Evaluation of Losartan Transdermal Patch by Using Solid Microneedles as A Physical Permeation Enhancer

Ericka Anguiano Almazan,
Pablo Serrano Castañeda,
Roberto Diaz Torres,
Jose Juan Escobar-Chavez*
PDFFinal Published
31
Jan
2020
NF-κB-dependent Mechanism of Action of c-Myc Inhibitor 10058-F4: Highlighting a Promising Effect of c-Myc Inhibition in Leukemia Cells, Irrespective of p53 Status
Original Article

NF-κB-dependent Mechanism of Action of c-Myc Inhibitor 10058-F4: Highlighting a Promising Effect of c-Myc Inhibition in Leukemia Cells, Irrespective of p53 Status

Mohammad Sayyadi,
Ava Safaroghli-Azar,
Majid Safa,
Hassan Abolghasemi,
Majid Momeny,
Davood Bashash*
PDFFinal Published
31
Jan
2020
Comprehensive Evaluation of Gene Expression in Negative and Positive Trigger-based Targeting Niosomes in HEK-293 Cell Line
Original Article

Comprehensive Evaluation of Gene Expression in Negative and Positive Trigger-based Targeting Niosomes in HEK-293 Cell Line

Mahmood Barani,
Masoud Torkzadeh-Mahani*,
Mohammad Mirzaei,
Mohammad Hadi Nematollahi
PDFFinal Published
31
Jan
2020
Design and Synthesis of Novel 1-hydroxy-2,4,5-triaryl Imidazole Derivatives as Anti-cytokine Agents
Original Article

Design and Synthesis of Novel 1-hydroxy-2,4,5-triaryl Imidazole Derivatives as Anti-cytokine Agents

Zahra Haghighijoo,
Omidreza Firuzi,
Savis Meili,
Najmeh Edraki,
Mehdi Khoshneviszadeh*,
Ramin Miri*
PDFFinal Published
31
Jan
2020
In-vitro Study of Hottentotta Schach Crude Venom Anticancer Effects on MCF-7 and Vero Cell Lines
Original Article

In-vitro Study of Hottentotta Schach Crude Venom Anticancer Effects on MCF-7 and Vero Cell Lines

Saeed Dezianian,
Jamil Zargan*,
Hamid Reza Goudarzi,
Ashkan Haji Noormohamadi,
Mohsen Mousavi,
Hani Keshavarz Alikhani
,et al.
PDFFinal Published
31
Jan
2020
Attributes Development for Pharmaceutical Subsidization: A Qualitative Study
Original Article

Attributes Development for Pharmaceutical Subsidization: A Qualitative Study

Gita Afsharmanesh,
Gholamhossein Mehralian*,
Farzad Peiravian
PDFFinal Published
31
Jan
2020
Analgesic, Anti-inflammatory and In-vitro Hyaluronidase Inhibitory Properties of the Leaf Extract and Solvent Fractions of Otostegia Fruticosa (Forssk.) Schweinf. ex Penzig.
Original Article

Analgesic, Anti-inflammatory and In-vitro Hyaluronidase Inhibitory Properties of the Leaf Extract and Solvent Fractions of Otostegia Fruticosa (Forssk.) Schweinf. ex Penzig.

Tiegsti Bahta,
Aman Karim*,
Gomathi Periasamy,
Gereziher Gebremedhin,
Najeeb ur-Rehman,
Helen Bitew
,et al.
PDFFinal Published
31
Jan
2020
Antidiabetic Properties of Hydroalcoholic Leaf and Stem Extract of Levisticum officinale: An implication for α-amylase Inhibitory Activity of Extract Ingredients through Molecular Docking
Original Article

Antidiabetic Properties of Hydroalcoholic Leaf and Stem Extract of Levisticum officinale: An implication for α-amylase Inhibitory Activity of Extract Ingredients through Molecular Docking

Nahid Ghaedi,
Iran Pouraboli*,
Nayere Askari
PDFFinal Published
31
Jan
2020
Docking, Synthesis and Evaluation of the Antifungal Activity of Pyrimido [4,5-b]quinolins
Original Article

Docking, Synthesis and Evaluation of the Antifungal Activity of Pyrimido [4,5-b]quinolins

Reza Araghi,
Bi Bi Fatemeh Mirjalili*,
Leila Zamani,
Soghra Khabnadideh,
Kamiar Zomoridian,
Zeinab Faghih
,et al.
PDFFinal Published
31
Jan
2020
LED Photo-polymerization, a Novel Strategy for Triggered Release Liposomes
Original Article

LED Photo-polymerization, a Novel Strategy for Triggered Release Liposomes

Afsoon Akbarzadeh,
Pezhman Sasanpour,
Hamid R. Moghimi*
PDFFinal Published
31
Jan
2020
Therapeutic Potential of Nanoparticle-loaded Hydroxyurea on Proliferation of Human Breast Adenocarcinoma Cell Line
Original Article

Therapeutic Potential of Nanoparticle-loaded Hydroxyurea on Proliferation of Human Breast Adenocarcinoma Cell Line

Fateme Azemati,
Bahman Jalali Kondori*,
Hadi Esmaeili Gouvarchin Ghaleh
PDFFinal Published
31
Jan
2020
Chemical Composition, Antioxidant, Genotoxique and Antigenotoxic Potentials of Phlomis Bovei De Noé Aerial Parts.
Original Article

Chemical Composition, Antioxidant, Genotoxique and Antigenotoxic Potentials of Phlomis Bovei De Noé Aerial Parts.

Nabila Zaabat,
Anne-Emmanuelle Hay,
Serge Michalet,
Inès Skandrani,
Leila Chekir-Ghedira,
Marie-Geneviève Dijoux-Franca
,et al.
PDFFinal Published
31
Jan
2020
Improvement of Ocular Efficacy of Levofloxacin by Bioadhesive Chitosan Coated PLGA Nanoparticles: Box-behnken Design, In-vitro Characterization, Antibacterial Evaluation and Scintigraphy Study
Original Article

Improvement of Ocular Efficacy of Levofloxacin by Bioadhesive Chitosan Coated PLGA Nanoparticles: Box-behnken Design, In-vitro Characterization, Antibacterial Evaluation and Scintigraphy Study

Ameeduzzafar,
Nazia Khan,
Nabil K Alruwaili,
Syed Nasir Abbas Bukhari,
Bader Alsuwayt,
Muhammad Afzal
,et al.
PDFFinal Published
31
Jan
2020
Therapeutic Effect of Carvacrol-loaded Albumin Nanoparticles on Arthritic Rats
Original Article

Therapeutic Effect of Carvacrol-loaded Albumin Nanoparticles on Arthritic Rats

Nasser Gholijani*,
Samira-Sadat Abolmaali,
Kurosh Kalantar,
Mohammad-Hadi Ravanrooy
PDFFinal Published
31
Jan
2020
Acetone Fraction of the Red Marine Alga Laurencia papillosa Reduces the Expression of Bcl-2 Anti-apoptotic Marker and Flotillin-2 Lipid Raft Marker in MCF-7 Breast Cancer Cells
Original Article

Acetone Fraction of the Red Marine Alga Laurencia papillosa Reduces the Expression of Bcl-2 Anti-apoptotic Marker and Flotillin-2 Lipid Raft Marker in MCF-7 Breast Cancer Cells

Josiane Elia,
Karina Petit*,
Jean-Michel Huvelin,
Mona Tannoury,
Mona Diab-Assaf,
Delphine Carbonnelle
,et al.
PDFFinal Published
31
Jan
2020
Noscapine Modulates Neuronal Response to Oxygen-glucose Deprivation/Reperfusion Injury Via Activation of Sigma-1 Receptor in Primary Cortical Cultures
Original Article

Noscapine Modulates Neuronal Response to Oxygen-glucose Deprivation/Reperfusion Injury Via Activation of Sigma-1 Receptor in Primary Cortical Cultures

Gelareh Vahabzadeh*,
Nahid Rahbar-Roshandel,
Soltan-Ahmad Ebrahimi
PDFFinal Published
31
Jan
2020
Exogenous Ghrelin Could Not Ameliorate 3,4-methylenedioxymethamphetamine-induced Acute Liver Injury in The Rat: Involved Mechanisms
Original Article

Exogenous Ghrelin Could Not Ameliorate 3,4-methylenedioxymethamphetamine-induced Acute Liver Injury in The Rat: Involved Mechanisms

Ravieh Golchoobian,
Fatemeh Nabavizadeh*,
Mehrdad Roghani,
Alireza Foroumadi,
Maryam Izad,
Maryam Bahrami
,et al.
PDFFinal Published
31
Jan
2020
A Preliminary Study of NER and MMR Pathways Involved in Chemotherapy Response in Bladder Transitional Cell Carcinoma: Impact on progression-free survival
Original Article

A Preliminary Study of NER and MMR Pathways Involved in Chemotherapy Response in Bladder Transitional Cell Carcinoma: Impact on progression-free survival

Vahideh Montazeri,
Mohammad Hossein Ghahremani,
Hamed Montazeri,
Mandana Hasanzad,
d, Majid Safavi,
Mohsen Ayati
,et al.
PDFFinal Published
31
Jan
2020
Preparation, Optimization and Characterization of Chitosan-coated Liposomes for Solubility Enhancement of Furosemide: A Model BCS IV Drug
Original Article

Preparation, Optimization and Characterization of Chitosan-coated Liposomes for Solubility Enhancement of Furosemide: A Model BCS IV Drug

Mohammad Moslehi,
S. Ali Reza Mortazavi,
Amir Azadi,
Samaneh Fateh,
Mehrdad Hamidi*,
S. Mohsen Foroutan*
PDFFinal Published
31
Jan
2020
Noncompetitive Inhibition of Bovine Liver Catalase by Lawsone: Kinetics, Binding Mechanism and in silico Modeling Approaches
Original Article

Noncompetitive Inhibition of Bovine Liver Catalase by Lawsone: Kinetics, Binding Mechanism and in silico Modeling Approaches

Simin khataee,
Gholamreza Dehghan,
Samaneh Rashtbari,
Siavash Dastmalchi,
Mehrdad Iranshahi
PDFFinal Published
31
Jan
2020
STAT3-mediated Apoptotic-enhancing Function of Sclareol Against Breast Cancer Cells and Cell Sensitization to Cyclophosphamide
Original Article

STAT3-mediated Apoptotic-enhancing Function of Sclareol Against Breast Cancer Cells and Cell Sensitization to Cyclophosphamide

Havva Afshari,
Mitra Nourbakhsh,
Niloufar Salehi,
Mohammad Mahboubi-Rabbani,
Afshin Zarghi,
Shokoofe Noori*
PDFFinal Published
31
Jan
2020
Development of a Sensitive and Rapid Method for Determination of Acrylamide in Bread by LC-MS/MS and Analysis of Real Samples in Iran IR
Original Article

Development of a Sensitive and Rapid Method for Determination of Acrylamide in Bread by LC-MS/MS and Analysis of Real Samples in Iran IR

Samira Eslamizad,
Farzad Kobarfard,
Kimia Tabib,
Hassan Yazdanpanah*,
Jamshid Salamzadeh
PDFFinal Published
31
Jan
2020
Antioxidant Activity and Hemocompatibility Study of Quercetin Loaded Plga Nanoparticles
Original Article

Antioxidant Activity and Hemocompatibility Study of Quercetin Loaded Plga Nanoparticles

Serap Derman*,
Deniz Uzunoglu,
Tayfun Acar,
Tulin Arasoglu,
Samet Ucak,
V Cengiz Ozalp
,et al.
PDFFinal Published
31
Jan
2020
Isolation, Purification and Antioxidant Activity of The Polysaccharides from Chinese Truffle Tuber sinense
Original Article

Isolation, Purification and Antioxidant Activity of The Polysaccharides from Chinese Truffle Tuber sinense

Caihong Zeng,
Xiaoyan Chen*,
Wenwen Jiang,
Yanling Liu,
Chunjuan Fang
PDFFinal Published
31
Jan
2020
Erythromycin Releasing PVA/sucrose and PVA/honey Hydrogels as Wound Dressings with Antibacterial Activity and Enhanced Bio-adhesion
Original Article

Erythromycin Releasing PVA/sucrose and PVA/honey Hydrogels as Wound Dressings with Antibacterial Activity and Enhanced Bio-adhesion

Shahrzad Fathollahipour,
Mojtaba Koosha*,
Javad Tavakoli,
Susan Maziarfar,
Jalil Fallah Mehrabadi
PDFFinal Published
31
Jan
2020
Logic of Selecting Suitable Dissolution Parameters in New Drug Formulations Based on A BCS Approach
Original Article

Logic of Selecting Suitable Dissolution Parameters in New Drug Formulations Based on A BCS Approach

Raúl Medina-López*,
Edgar E. Arregui,
Edson J. Aranda,
Luis A. Moreno-Rocha,
Marcela Hurtado,
Helgi Jung-Cook
,et al.
PDFFinal Published
31
Jan
2020
Novel Bi-heterocycles as Potent Inhibitors of Urease and Less Cytotoxic Agents: 3-({5-((2-Amino-1,3-thiazol-4-yl)methyl)-1,3,4-oxadiazol-2-yl}sulfanyl)-N-(un/substituted-phenyl)propanamides
Original Article

Novel Bi-heterocycles as Potent Inhibitors of Urease and Less Cytotoxic Agents: 3-({5-((2-Amino-1,3-thiazol-4-yl)methyl)-1,3,4-oxadiazol-2-yl}sulfanyl)-N-(un/substituted-phenyl)propanamides

Muhammad Athar Abbasi*,
Muhammad Shahid Ramzan,
Aziz ur-Rehman,
Sabahat Zahra Siddiqui,
Mubashir Hassan,
Syed Adnan Ali Shah
,et al.
PDFFinal Published