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Iranian Journal of Pharmaceutical Research

e-ISSN 1726-6890
p-ISSN 1735-0328
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Volume 18, Issue 3

45 articles2019-07-31Vol. 18Issue 3XML
31
Jul
2019
Mathematical Modeling and Release Kinetics of Green Tea Polyphenols Released from Casein Nanoparticles
Original Article

Mathematical Modeling and Release Kinetics of Green Tea Polyphenols Released from Casein Nanoparticles

Ravi Theaj Prakash Upputuri,
Abul Kalam Azad Mandal*
PDFFinal Published
31
Jul
2019
A New Model to Describe the Single-dose Pharmacokinetics of Bevacizumab and Predict Its Multiple-Dose Pharmacokinetics in Beagle Dogs
Original Article

A New Model to Describe the Single-dose Pharmacokinetics of Bevacizumab and Predict Its Multiple-Dose Pharmacokinetics in Beagle Dogs

Meizhen Li,
Wei Qiang,
Zhou Wen,
Linling Li,
Lei Wang,
Zeneng Cheng*
PDFFinal Published
31
Jul
2019
Semi-IPN Films and Electrospun Nanofibers Based on Chitosan/PVA as an Antibacterial Wound Dressing
Original Article

Semi-IPN Films and Electrospun Nanofibers Based on Chitosan/PVA as an Antibacterial Wound Dressing

Keshvad Hedayatyanfard,
Shadab Bagheri-Khoulenjani,
Ali Hashemi,
Seyed Ali Ziai*
PDFFinal Published
31
Jul
2019
Comparative of in-vitro Evaluation between Erlotinib Loaded Nanostructured Lipid Carriers and Liposomes against A549 Lung Cancer Cell Line
Original Article

Comparative of in-vitro Evaluation between Erlotinib Loaded Nanostructured Lipid Carriers and Liposomes against A549 Lung Cancer Cell Line

Fereydoon Abedi Gaballu,
Soheil Abbaspour-Ravasjani,
Behzad Mansoori,
Reza Yekta,
Hamed Hamishehkar,
Ali Mohammadi
,et al.
PDFFinal Published
31
Jul
2019
Chitosan-Coated Alginate Microcapsules Loaded with Herbal galactagogue Extract: Formulation Optimization and Characterization
Original Article

Chitosan-Coated Alginate Microcapsules Loaded with Herbal galactagogue Extract: Formulation Optimization and Characterization

Nasim Khorshidian,
Arash Mahboubi,
Naser Kalantari,
Hedayat Hosseini,
Mojtaba Yousefi,
Masoumeh Arab
,et al.
PDFFinal Published
31
Jul
2019
Facile Synthesis and Characterization of Ibuprofen-mesoporous Hydroxyapatite Nanohybrid as a Sustained Drug Delivery System
Original Article

Facile Synthesis and Characterization of Ibuprofen-mesoporous Hydroxyapatite Nanohybrid as a Sustained Drug Delivery System

Zahra Namazi,
Tahereh Sadat Jafarzadeh Kashi,
Mohammad Erfan*,
Farhood Najafi,
Leila Bakhtiari,
Seyed Rohola Ghodsi
,et al.
PDFFinal Published
31
Jul
2019
Physical Separation of Amphiprotic-Polar AproticS for Simultaneous Extraction and Clean-up of Clomiphene from Plasma before Liquid Chromatographic Analysis
Original Article

Physical Separation of Amphiprotic-Polar AproticS for Simultaneous Extraction and Clean-up of Clomiphene from Plasma before Liquid Chromatographic Analysis

Farhad Ahmadi*,
Nilofar Rahmani
PDFFinal Published
31
Jul
2019
Validation of an Analytical Method for Simultaneous Determination of 18 Persistent Organic Pollutants in Trout Using LLE Extraction and GC-MS/MS
Original Article

Validation of an Analytical Method for Simultaneous Determination of 18 Persistent Organic Pollutants in Trout Using LLE Extraction and GC-MS/MS

Mitra Bayat,
Mohammad Saber tehrani*,
Farzad Kobarfard,
Syed Waqif Husain,
Hassan Yazdanpanah
PDFFinal Published
31
Jul
2019
Application of Genetic Algorithms for Pixel Selection in MIA-QSAR Studies on Anti-HIV HEPT Analogues for New Design Derivatives
Original Article

Application of Genetic Algorithms for Pixel Selection in MIA-QSAR Studies on Anti-HIV HEPT Analogues for New Design Derivatives

Zohreh Doroudi,
Ali Niazi*
PDFFinal Published
31
Jul
2019
Molecular Docking and QSAR Study of 2-Benzoxazolinone, Quinazoline and Diazocoumarin Derivatives as Anti-HIV-1 Agents
Original Article

Molecular Docking and QSAR Study of 2-Benzoxazolinone, Quinazoline and Diazocoumarin Derivatives as Anti-HIV-1 Agents

Kamyar Faghihi,
Mahdieh Safakish,
Tannaz Zebardast,
Zahra Hajimahdi*,
Afshin Zarghi*
PDFFinal Published
31
Jul
2019
Synthesis of a Peptide Derivative of MicrocinJ25 and Evaluation of Antibacterial and Biological Activities
Original Article

Synthesis of a Peptide Derivative of MicrocinJ25 and Evaluation of Antibacterial and Biological Activities

Maryam Mazaheri Tehrani,
Mostafa Erfani*,
Nour Amirmozafari,
Taher Nejadsattari
PDFFinal Published
31
Jul
2019
Efficient Synthesis of Norbuprenorphines Coupled with Enkephalins and Investigation of Their Permeability
Original Article

Efficient Synthesis of Norbuprenorphines Coupled with Enkephalins and Investigation of Their Permeability

Saeed Balalaie*,
Morteza Malakoutikhah,
Meritxell Teixidó,
Vaezeh Fathi Vavsari,
Ernest Giralt,
Yaghoub Haghighatnia
,et al.
PDFFinal Published
31
Jul
2019
Synthesis and Biological Assessment of 2-Hydroxyiminoethanones as Anti-Inflammatory and β-Amyloid Aggregation Inhibitors
Original Article

Synthesis and Biological Assessment of 2-Hydroxyiminoethanones as Anti-Inflammatory and β-Amyloid Aggregation Inhibitors

Mehdi Valipour,
Issa Davaji,
Niusha Abedi,
Mahsa Rajabi,
Tuba Tüylü Küçükkılınç,
Beyza Ayazgök
,et al.
PDFFinal Published
31
Jul
2019
Design and Synthesis of Novel Triazole-based Peptide Analogues as Anticancer Agents
Original Article

Design and Synthesis of Novel Triazole-based Peptide Analogues as Anticancer Agents

Maryam Baharloui,
Sayed Ahmmad Mirshokraee,
Azam Monfared,
Mohammad Hassan Houshdar Tehrani*
PDFFinal Published
31
Jul
2019
Therapeutic Effects of Nano-HAp in a Rat Model of AlCl3 Induced Neurotoxicity
Original Article

Therapeutic Effects of Nano-HAp in a Rat Model of AlCl3 Induced Neurotoxicity

Osma Ahmed Abbas*,
Issa Ghada Ibrahim,
Abdel-Gawad Eman Ismail
PDFFinal Published
31
Jul
2019
Novel Palladium Complex: Cytotoxicity against Cisplatin-resistant K562 Cells
Original Article

Novel Palladium Complex: Cytotoxicity against Cisplatin-resistant K562 Cells

Ali Jahanian-Najafabadi,
Mina Mirian,
Fatemeh Rohani,
Kazem Karami,
Mahboubeh Hosseini Kharat,
Hojjat Sadeghi-Aliabadi*
PDFFinal Published
31
Jul
2019
Exposure to Aflatoxin M1 through Milk Consumption in Tehran Population, Iran
Original Article

Exposure to Aflatoxin M1 through Milk Consumption in Tehran Population, Iran

Hamid Khaneghahi Abyaneh,
Alireza Bahonar*,
Negin Noori,
Hassan Yazdanpanah,
Mohammad Hossein Shojaee AliAbadi
PDFFinal Published
31
Jul
2019
Protective Effect of Dizocilpine (MK-801) On TNBS-Induced Experimental Colitis in Mice
Original Article

Protective Effect of Dizocilpine (MK-801) On TNBS-Induced Experimental Colitis in Mice

Ehsan Motaghi,
Valiollah Hajhashemi,
Parvin Mahzouni,
Mohsen Minaiyan*
PDFFinal Published
31
Jul
2019
Calixmexitil: Calixarene-based Cluster of Mexiletine with Amplified Anti-myotonic Activity as A Novel Use-dependent Sodium Channel Blocker
Original Article

Calixmexitil: Calixarene-based Cluster of Mexiletine with Amplified Anti-myotonic Activity as A Novel Use-dependent Sodium Channel Blocker

Amirali Delnavaz Shahr,
Fazel Nasuhi Pur*
PDFFinal Published
31
Jul
2019
The Relaxant Effect of Crocin on Rat Tracheal Smooth Muscle and Its Possible Mechanisms
Original Article

The Relaxant Effect of Crocin on Rat Tracheal Smooth Muscle and Its Possible Mechanisms

Saeideh Saadat,
Mahsa Yasavoli,
Zahra Gholamnezhad,
Mohammad Reza Aslani,
Mohammad Hossein Boskabady*
PDFFinal Published
31
Jul
2019
Thiazolidinedione Derivative Suppresses LPS-induced COX-2 Expression and NO Production in RAW 264.7 Macrophages
Original Article

Thiazolidinedione Derivative Suppresses LPS-induced COX-2 Expression and NO Production in RAW 264.7 Macrophages

Mehrnaz Rezaei,
Hossein Ghafouri*,
Mahmood Reza Aghamaali,
Mostafa Shourian
PDFFinal Published
31
Jul
2019
Carvacrol Ameliorates Pathological Cardiac Hypertrophy in Both In-vivo and In-vitro Models
Original Article

Carvacrol Ameliorates Pathological Cardiac Hypertrophy in Both In-vivo and In-vitro Models

Mohabbat Jamhiri,
Farzan Safi Dahaj,
Akram Astani,
Seyed Hasan Hejazian,
Zeynab Hafizibarjin,
Mojtaba Ghobadi
,et al.
PDFFinal Published
31
Jul
2019
The Protective Effect of Auraptene Against Oxidative Stress and Pentylenetetrazol-Induced Chemical Kindling in Mice
Original Article

The Protective Effect of Auraptene Against Oxidative Stress and Pentylenetetrazol-Induced Chemical Kindling in Mice

Leila Etemad,
Mahdieh Zamani,
Mehrdad Iranshahi,
Ali Roohbakhsh*
PDFFinal Published
31
Jul
2019
Peroxisome Proliferator-activated Receptor (PPAR)-γ Modifies Aβ Neurotoxin-induced Electrophysiological Alterations in Rat Primary Cultured Hippocampal Neurons
Original Article

Peroxisome Proliferator-activated Receptor (PPAR)-γ Modifies Aβ Neurotoxin-induced Electrophysiological Alterations in Rat Primary Cultured Hippocampal Neurons

Farideh Bahrami,
Alireza Asgari,
Narges Hosseinmardi,
Mahyar Janahmadi*
PDFFinal Published
31
Jul
2019
Trehalose Neuroprotective Effects on the Substantia Nigra Dopaminergic Cells by Activating Autophagy and Non-canonical Nrf2 Pathways
Original Article

Trehalose Neuroprotective Effects on the Substantia Nigra Dopaminergic Cells by Activating Autophagy and Non-canonical Nrf2 Pathways

Shahram Darabi*,
Ali Noori-Zadeh,
Hojjat-Allah Abbaszadeh*,
Farzad Rajaei,
Salar Bakhtiyari
PDFFinal Published
31
Jul
2019
Prelimbic of Medial Prefrontal Cortex GABA Modulation through Testosterone on Spatial Learning and Memory
Original Article

Prelimbic of Medial Prefrontal Cortex GABA Modulation through Testosterone on Spatial Learning and Memory

Azadeh Gholaminejad,
Hamid Gholamipour-Badie,
Mohammad Nasehi,
Nasser Naghdi*
PDFFinal Published
31
Jul
2019
Mitochondrial Complex I Is an Essential Player in LPS-Induced Preconditioning in Differentiated PC12 Cells
Original Article

Mitochondrial Complex I Is an Essential Player in LPS-Induced Preconditioning in Differentiated PC12 Cells

Nasim Manouchehri,
Fariba Khodagholi,
Leila Dargahi,
Abolhassan Ahmadiani*
PDFFinal Published
31
Jul
2019
An In-Vivo Study on Anticonvulsant, Anxiolytic, and Sedative-Hypnotic Effects of the Polyphenol-Rich Thymus Kotschyanus Extract; Evidence for the Involvement of GABAA Receptors
Original Article

An In-Vivo Study on Anticonvulsant, Anxiolytic, and Sedative-Hypnotic Effects of the Polyphenol-Rich Thymus Kotschyanus Extract; Evidence for the Involvement of GABAA Receptors

Reza Jahani,
Faraz Mojab,
Arash Mahboubi,
Azadeh Nasiri,
Armin Tahamtani,
Mehrdad Faizi*
PDFFinal Published
31
Jul
2019
Calcium Channel Blockade Ameliorates Endoplasmic Reticulum Stress in the Hippocampus Induced by Amyloidopathy in the Entorhinal Cortex
Original Article

Calcium Channel Blockade Ameliorates Endoplasmic Reticulum Stress in the Hippocampus Induced by Amyloidopathy in the Entorhinal Cortex

Azam Ghanbari-Maman,
Forouzan Ghasemian-Roudsari,
Shayan Aliakbari,
Hamid Gholami Pourbadie*,
Fariba Khodagholi,
Fatemeh Shaerzadeh
,et al.
PDFFinal Published
31
Jul
2019
Anticancer Activity of Polyisoprenoids from Avicennia alba Blume. in WiDr Cells
Original Article

Anticancer Activity of Polyisoprenoids from Avicennia alba Blume. in WiDr Cells

Didi Nurhadi Illian,
Poppy Anjelisa Zaitun Hasibuan,
Sumardi Sumardi,
Arif Nuryawan,
Ridha Wati,
Mohammad Basyuni*
PDFFinal Published
31
Jul
2019
Anti-Inflammatory and Anti-Oxidative Effects of Myrtenol in the Rats with Allergic Asthma
Original Article

Anti-Inflammatory and Anti-Oxidative Effects of Myrtenol in the Rats with Allergic Asthma

Mohammad Amin Rajizadeh,
Hamid Najafipour*,
Mitra Samareh Fekr,
Farzaneh Rostamzadeh,
Elham Jafari,
Mohammad Abbas Bejeshk
,et al.
PDFFinal Published
31
Jul
2019
Purification of Sesquiterpenes from Saussurea Lappa Roots by High Speed Counter Current Chromatography
Original Article

Purification of Sesquiterpenes from Saussurea Lappa Roots by High Speed Counter Current Chromatography

Kun Cao,
Wei Qian,
Yi Xu*,
Zhen Zhou
PDFFinal Published
31
Jul
2019
Natural Alpha-Glucosidase Inhibitors Rapid Fishing from Cyperus Rotundus Using Immobilized Enzyme Affinity Screening Combined with UHPLC-QTOF MS
Original Article

Natural Alpha-Glucosidase Inhibitors Rapid Fishing from Cyperus Rotundus Using Immobilized Enzyme Affinity Screening Combined with UHPLC-QTOF MS

Shiren Deng*,
Linbo Xia*,
Xiamin Zhu,
Jiang Zhu,
Mingchen Cai,
Xin Wang
PDFFinal Published
31
Jul
2019
Antimicrobial Activities of Extracts and Isolated Coumarins from the Roots of Four Ferulago Species Growing in Turkey
Original Article

Antimicrobial Activities of Extracts and Isolated Coumarins from the Roots of Four Ferulago Species Growing in Turkey

Songül Karakaya*,
Duygu Şimşek,
Hilal Özbek,
Zühal Güvenalp,
Nurten Altanlar,
Cavit Kazaz
,et al.
PDFFinal Published
31
Jul
2019
Cardioprotective Effect of Ethanolic Leaf Extract of Melissa Officinalis L Against Regional Ischemia-Induced Arrhythmia and Heart Injury after Five Days of Reperfusion in Rats
Original Article

Cardioprotective Effect of Ethanolic Leaf Extract of Melissa Officinalis L Against Regional Ischemia-Induced Arrhythmia and Heart Injury after Five Days of Reperfusion in Rats

Mehrnoosh Sedighi,
Mahdieh Faghihi,
Mahmoud Rafieian-Kopaei,
Bahram Rasoulian,
Afshin Nazari*
PDFFinal Published
31
Jul
2019
Phytochemical Analysis and Various Biological Activities of the Aerial Parts of Scrophularia Atropatana Growing in Iran
Original Article

Phytochemical Analysis and Various Biological Activities of the Aerial Parts of Scrophularia Atropatana Growing in Iran

Solmaz Asnaashari,
Abbas Delazar,
Elham Safarzadeh,
Hamed Tabibi,
Saeed Mollaei,
Ali Rajabi
,et al.
PDFFinal Published
31
Jul
2019
Improving Activity of Lycium Barbarum. Polysaccharide on Depressive Mice Induced by Reserpine
Original Article

Improving Activity of Lycium Barbarum. Polysaccharide on Depressive Mice Induced by Reserpine

Rui Zhao*,
Bing Qiu Master,
Baoling Ma Master,
Yaping Cai
PDFFinal Published
31
Jul
2019
Optimization of the Four Most Effective Factors on β-Carotene Production by Dunaliella salina Using Response Surface Methodology
Original Article

Optimization of the Four Most Effective Factors on β-Carotene Production by Dunaliella salina Using Response Surface Methodology

Leila Zarandi-Miandoab,
Mohammad-Amin Hejazi*,
Mohammad-Bagher Bagherieh-Najjar,
Nader Chaparzadeh
PDFFinal Published
31
Jul
2019
Genotyping of Pseudomonas Aeruginosa Strains As A Multidrug Resistant (MDR) Bacterium And Evaluating The Prevalence of Esbls and Some Virulence Factors Encoding Genes By PFGE and ERIC-PCR Methods
Original Article

Genotyping of Pseudomonas Aeruginosa Strains As A Multidrug Resistant (MDR) Bacterium And Evaluating The Prevalence of Esbls and Some Virulence Factors Encoding Genes By PFGE and ERIC-PCR Methods

Alireza Mokhtari,
Kumarss Amini*
PDFFinal Published
31
Jul
2019
A Randomized Clinical Trial of Elemental Zinc Add-on Therapy on Clinical Outcomes of Patients with Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP)
Original Article

A Randomized Clinical Trial of Elemental Zinc Add-on Therapy on Clinical Outcomes of Patients with Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP)

Nader Akbari Dilmaghani*,
Nadereh Alani,
Sepideh Fazeli
PDFFinal Published
31
Jul
2019
Effect of a Natural Eye Drop, Made of Plantago Ovata Mucilage on Improvement of Dry Eye Symptoms: A Randomized, Double-blind Clinical Trial
Original Article

Effect of a Natural Eye Drop, Made of Plantago Ovata Mucilage on Improvement of Dry Eye Symptoms: A Randomized, Double-blind Clinical Trial

Neda Haji-Ali-Nili,
Fariba Khoshzaban*,
Mehrdad Karimi,
Roja Rahimi,
Elham Ashrafi,
Reza Ghaffari
,et al.
PDFFinal Published
31
Jul
2019
Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L.) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial
Original Article

Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L.) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial

Marya Kabiri,
Mohammad Kamalinejad,
Soodabeh Bioos,
Mamak Shariat,
Farnaz Sohrabvand*
PDFFinal Published
31
Jul
2019
Tenecteplase Versus Reteplase in Acute Myocardial Infarction: A Network Meta-Analysis of Randomized Clinical Trials
Original Article

Tenecteplase Versus Reteplase in Acute Myocardial Infarction: A Network Meta-Analysis of Randomized Clinical Trials

Majid Zia-Behbahani,
Hossein Niknahad,
Javad Kojuri,
Mahmood Salesi,
Mojtaba jafari,
Khosro Keshavarz*
PDFFinal Published
31
Jul
2019
A Comparison Study of Efficacy and Safety of a Biosimilar Form of Intramuscular Βeta-interferon I-a Versus the Reference Product: A Randomized Controlled Clinical Trial in Iran
Short Communication_imported

A Comparison Study of Efficacy and Safety of a Biosimilar Form of Intramuscular Βeta-interferon I-a Versus the Reference Product: A Randomized Controlled Clinical Trial in Iran

Seyed Massood Nabavi,
Roya Abolfazli,
Ali Etemadrezaei,
Hamed Hosseini,
Nahid Moradi,
Sanaz Shahriari
,et al.
PDFFinal Published
31
Jul
2019
FDA Approved Drugs Repurposing of Toll-Like Receptor4 (TLR4) Candidate for Neuropathy
Original Article

FDA Approved Drugs Repurposing of Toll-Like Receptor4 (TLR4) Candidate for Neuropathy

Hakimeh Zali,
Ali Golchin,
Masoumeh Farahani,
Mohsen Yazdani,
Mohammad Mehdi Ranjbar,
Ali Dabbagh*
PDFFinal Published