Jundishapur Journal of Microbiology
L-tryptophan (L-Trp) is a nutritionally essential amino acid that the body uses to synthesize proteins, niacin (vitamin B3) and serotonin (neurotransmitters). Human and animals depend on plants and microorganisms for its supply. Remarkable increasing demand has caused the development of a wide variety of biotechnological methods for its production which work as well for other amino acids.
The present work reports on the use of Iranian sugar beet molasses as an inexpensive source of L-serine (precursor) and PLP (cofactor) for the production of L-Trp by
Consequently, the potassium phosphate buffer system was considered as the suitably buffered reaction medium. The concentration of L-Trp produced in reaction medium was 0.3 mM and 0.12 mM for glucose and molasses (a combination of sugar beet and cane molasses), respectively.
our present study shows that sugar beet molasses is a source of PLP and L-Ser; and hence, suggests the general application of the approach to produce L-Trp more economically.
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Sadeghiyan-Rizi T, Fooladi J, Momhed Heravi M, Sadrai S. Optimization of L-Tryptophan Biosynthesis From L-Serine of Processed Iranian Beet and Cane Molasses and Indole by Induced Escherichia coliATCC 11303 Cells. Jundishapur J Microbiol. 2014;7(6):e10589. doi: https://doi.org/10.5812/jjm.10589
Yadegary M, Hamidi A, Alavi SA, Khodaverdi E, Yahaghi H, et al. Citric Acid Production From Sugarcane Bagasse through Solid State Fermentation Method Using Aspergillus niger Mold and Optimization of Citric Acid Production by Taguchi Method. Jundishapur J Microbiol. 2013;6(9):e7625. doi: https://doi.org/10.5812/jjm.7625
Ghezelbash G, Nahvi I, Rabbani M. Study of polyols production by Yarrowia lipolytica in batch culture and optimization of growth condition for maximum production. Jundishapur J Microbiol. 2012;5(4):546-549. doi: https://doi.org/10.5812/jjm.3524
Zarei O, Dastmalchi S, Hamzeh-Mivehroud M. A Simple and Rapid Protocol for Producing Yeast Extract from Saccharomyces cerevisiae Suitable for Preparing Bacterial Culture Media. Iran J Pharm Res. 2016;15(4):e125210. doi: https://doi.org/10.22037/ijpr.2016.1915
Khalaf Shamsabadi F, Mirzaee M, Baharifar N, Sheikh A, Sheikhi S, et al. In Vitro Immunomodulatory Effects of Sugar-Free Sugarcane Molasses and Bifidobacterium animalis subsp. lactis on IFN-γ and TGF-β Secretion in Ulcerative Colitis Patients. J Adv Immunopharmacol. 2024;4(1):e142990. doi: https://doi.org/10.5812/jai-142990
Checking
Last Update: 1 week ago
Last Update: 1 week ago
Last Update: 1 week ago
Last Update: 6 days ago
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Author(s):
