Archive

vol. 22 , issue 1
62 articles
2023
09
Apr
2023

Hepatotoxicity Induced by Azole Antifungal Agents: A Review Study

Amin Rakhshan, Bardia Rahmati Kamel, Ali Saffaei ORCID , Maria Tavakoli-Ardakani ORCID *
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Final Published
31
Jul
2023

Ginkgo biloba Efficacy in the Treatment of Drug-Induced Parkinsonism: A Randomized Clinical Trial

Niayesh Mohebbi, Arash Kalantar Mehrjardi, Maryam Mousavi, Maryam Taghizadeh-Ghehi, Mahya Rezaie, Zahra Hooshyari, et al.
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Final Published
19
Jun
2023
Iran J Pharm Res

Investigating the Relationship Between the Market Orientation Approach of Pharmaceutical Companies and Their Innovative Performance: The Mediating Role of Dynamic Capabilities and Corporate Social Responsibility

Javad Shirmohammadi, Shahriar Azizi, Hamid Reza Rasekh * , Farzad Peiravian ORCID , Mahyar Polroudi Moghaddam
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Final Published
28
Oct
2023
Iran J Pharm Res

In Vitro Chondrogenic Differentiation of Human Adipose-Derived Stem Cells by Diacerein

Ali Honarpardaz ORCID , Morteza Daliri Joupari ORCID * , Sajjad Tavakkoli
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Final Published
10
Sep
2023
Iran J Pharm Res

Designing and Expression of Recombinant Chimeric Spike Protein from SARS-CoV-2 in Escherichia coli and Its Immunogenicity Assessment

Sahar Karimi ORCID , Shahram Nazarian ORCID , Fattah Sotoodehnejadnematalahi ORCID , Roohollah Dorostkar ORCID , Jafar Amani ORCID *
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Final Published
21
Jun
2023
Iran J Pharm Res

Effects of Komouni Formulation (Herbal Product of Persian Medicine) With a Low-Calorie Diet on Cardiometabolic Risk Factors in Overweight and Obese Women: A Triple-Blinded Randomized Clinical Trial

Zahra Aghabeiglooei ORCID , Nazli Namazi ORCID * , Mehrdad Karimi ORCID , Samaneh Soleymani ORCID , Mohammad Hossein Ayati ORCID , Hossein Rezaeizadeh ORCID **
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Final Published
30
Sep
2023
Iran J Pharm Res

Integration of Machine Learning and Structural Analysis for Predicting Peptide Antibiofilm Effects: Advancements in Drug Discovery for Biofilm-Related Infections

Fatemeh Ebrahimi Tarki, Mahboobeh Zarrabi ORCID * , Ahya Abdiali ORCID , Mahkame Sharbatdar ORCID
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Final Published
26
Aug
2023
Iran J Pharm Res

The Efficacy of High-Dose Pulse Therapy vs. Low-Dose Intravenous Methylprednisolone on Severe to Critical COVID-19 Clinical Outcomes: A Randomized Clinical Trial

Zahra Sahraei, Parnaz Panahi, Kouroush Solhjoukhah, Maryam Mesbah, Siamak Afaghi ORCID , Mahdi Amirdosara, et al.
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Final Published
23
Mar
2023
Iran J Pharm Res

Amphotericin B Pharmacokinetics: Inter-strain Differences in Rats Following Intravenous Administration of the Most Commonly Marketed Formulations of the Drug

Erfan Abdollahizad, Simin Dadashzadeh ORCID * , Shima Bahri, Zahra Abbasian, Elham Rezaee ORCID
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Final Published
22
Jun
2023
Iran J Pharm Res

A Mechanistic Study on the Fluidization and Enhancement Effects of Cineole Toward Stratum Corneum Intercellular Lamellar Lipids: A Liquid Crystalline Model Approach

Leila Karami, Hamid Reza Moghimi ORCID *
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Final Published
01
Sep
2023
Iran J Pharm Res

Efficacy of Probiotics in Improving Motor Function and Alleviating Constipation in Parkinson’s Disease: A Randomized Controlled Trial

Nasibeh Ghalandari ORCID , Farhad Assarzadegan, Seyed Amir Hassan Habibi, Hadi Esmaily ORCID * , Habib Malekpour
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Final Published
07
Apr
2023
Innov J Pharm Res

Chinese Medicine Enhancing Response Rates to Immunosuppressant PD-L1 Inhibitor and Improving the Quality of Life of Hepatocellular Carcinoma-Bearing Mice

Lixing Liu * , Hao Li, Peijin Li, Rui Zhou, Qinglin Zhang, Tingting Liu, et al.
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Final Published
07
Apr
2023
Innov J Pharm Res

Hyaluronic Acid-modified Liposomes for Ursolic Acid-targeted Delivery Treat Lung Cancer Based on p53/ARTS-mediated Mitochondrial Apoptosis

TingTing Ma, Jiasi Zhou, Jiajie Li, Qi Chen *
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Final Published
08
Apr
2023

The Effect of Donor Rat Gender in Mitochondrial Transplantation Therapy of Cisplatin-Induced Toxicity on Rat Renal Proximal Tubular Cells

Abdollah Arjmand, Mehrdad Faizi, Mohsen Rezaei, Jalal Pourahmad *
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Final Published
17
Apr
2023
Innov J Pharm Res

Consumers’ Willingness to Pay for Pharmacist Counselling Services and the Factors Affecting It in Community Pharmacies

Omid Soodi, Elahe Hesari, Reza Hojjatifard, Meysam Seyedifar ORCID *
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Final Published
19
May
2023
Iran J Pharm Res

Dissolving Microneedles Loaded with Gestodene: Fabrication and Characterization In Vitro and In Vivo

Xueyan Duan, Jianan Ma, Meiying Ning * , Yunhua Gao **
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Final Published
14
Apr
2023
Innov J Pharm Res

Calcium Dobesilate Ameliorates Cisplatin-induced Hepatotoxicity by Inhibiting Liver Oxidative Stress in Mice

Gholamreza Bazmandegan ORCID , Zahra Kamiab, Amirmohammad Shafiei, Morteza Khademalhosseini ORCID , Ayat Kaeidi ORCID *
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Final Published
17
Apr
2023
Innov J Pharm Res

In Vitro and In Vivo Antidiabetic, α-Glucosidase Inhibition and Antibacterial Activities of Three Brown Algae, Polycladia myrica, Padina antillarum, and Sargassum boveanum, and a Red Alga, Palisada perforata from the Persian Gulf

Niloofar Moheimanian, Hossein Mirkhani, Azar Purkhosrow, Jelveh Sohrabipour, Amir Reza Jassbi *
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Final Published
18
Apr
2023
Innov J Pharm Res

Synthesis, Antioxidant, Cytotoxicity, Induce Apoptosis Investigation and Docking Study of New Halogenated Dihydropyrano[3,2-b]Chromene-3-Carbonitrile Derivatives on MCF-7 Breast Cancer Cell Line

Touba Eslaminejad ORCID , Ehsan Faghih Mirzaei ORCID , Mehdi Abaszadeh ORCID *
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Final Published
25
Apr
2023
Innov J Pharm Res

Comparison of the Polyamine Content of Five Spring Flowers with Wheat Germ as a Rich Anti-aging Polyamine Source for Preparation of Nutraceutical Products

Maryam Mohajeri ORCID , Seyed Abdulmajid Ayatollahi, Mohammad Goli, Shaya Mokhtari ORCID , Maryam Khandan ORCID , Azadeh Nasiri, et al.
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Final Published
10
Jul
2023
Iran J Pharm Res

Hepatic Steatosis Alleviated by a Novel Metformin and Quercetin Combination Activating Autophagy Through the cAMP/AMPK/SIRT1 Pathway

Havva Afshari, Shokoofe Noori ORCID * , Afshin Zarghi ORCID
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Final Published
06
Jul
2023
Iran J Pharm Res

In vitro Evaluation of the Potent Antileishmanial Activity of Ferula tabasensis Alone or in Combination with Shark Cartilage Extract Against the Standard Iranian Strain of Leishmania major (MRHO/IR/75/ER)

Shaylin Saraei ORCID , Narges Soozangar ORCID , Mansour Miran ORCID , Fatemeh Ghaffarifar, Behnam Mohammadi-Ghalehbin ORCID , Soheila Molaei ORCID * , et al.
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Final Published
24
Jun
2023
Iran J Pharm Res

The Effect of Lipopolysaccharide-Stimulated Adipose-Derived Mesenchymal Stem Cells on NAFLD Treatment in High-Fat Diet-Fed Rats

Reza Afarin ORCID , Fereshteh Aslani, Shahla Asadizade, Bahar Jaberian Asl, Mehrnoosh Mohammadi Gahrooie, Elham Shakerian ORCID , et al.
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Final Published
18
Jun
2023
Iran J Pharm Res

The Expression of miR-34c-5p Induces G0/G1 Cell Cycle Arrest and Apoptosis in SW480 Colon Cancer Cell

Shirin Farzaneh, Shabnam Bandad, Faezeh Shaban, Masoumeh Heshmati * , Nooshin Barikrow, Sanaz Pashapour ORCID
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Final Published
19
Jun
2023
Iran J Pharm Res

Co-treatment of Naringenin and Ketoprofen-RGD Suppresses Cell Proliferation via Calmodulin/PDE/cAMP/PKA Axis Pathway in Leukemia and Ovarian Cancer Cells

Havva Afshari, Shokoofe Noori ORCID * , Bahareh Shokri, Afshin Zarghi ORCID
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Final Published
23
Jul
2023
Iran J Pharm Res

Bacillus coagulans T4 and Lactobacillus paracasei TD3 Ameliorate Skeletal Muscle Oxidative Stress and Inflammation in High-Fat Diet-Fed C57BL/6J Mice

Masoumeh Shams, Fataneh Esmaeili, Samira Sadeghi, Mahsa Shanaki-Bavarsad, Shadi Sadat Seyyed Ebrahimi, Seyyed Mohammad Reza Hashemnia, et al.
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Final Published
06
Aug
2023
Iran J Pharm Res

Chemical Composition Analysis of Atropa belladonna Grown in Iran and Evaluation of Antibacterial Properties of Extract-loaded Nanofibers

Elmira Danaie, Shiva Masoudi * , Nasrin Masnabadi
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Final Published
11
Oct
2023
Iran J Pharm Res

Evaluation of the Relationship Between Serum miR-200b-3p and miR-214-3p Expression Levels with Soluble ACE2 and TMPRSS2 in COVID-19 Patients

Faezeh Mortazavi ORCID , Mohsen Soltanshahi ORCID , Gholamhossein Tamaddon ORCID *
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Final Published
11
Jul
2023
Iran J Pharm Res

NBP Cytoprotective Effects Promoting Neuronal Differentiation in BMSCs by Inhibiting the p65/Hes1 Pathway

Eryi Zhao, Peijian Huang, Zhongyan Zhao, Shixiong Huang, Shijun Hu, Ling Xie, et al.
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Final Published
11
Jul
2023
Iran J Pharm Res

Evaluation of Antioxidant and Antibacterial Effects of Lyophilized Cell-Free Probiotic Supernatants of Three Lactobacillus spp. and Their Cytocompatibility Against Periodontal Ligament Stem Cells

Maryam Torshabi ORCID , Mohammad Mahdi Bardouni ORCID , Atieh Hashemi ORCID *
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Final Published
14
Oct
2023
Iran J Pharm Res

Froriepia subpinnata Leaf Extract-Induced Apoptosis in the MCF-7 Breast Cancer Cell Line by Increasing Intracellular Oxidative Stress

Hanieh Rostamabadi, Mohammad Rasoul Samandari Bahraseman * , Keyvan Esmaeilzadeh-Salestani
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Final Published
14
Oct
2023
Iran J Pharm Res

Synthesis and Biological Evaluation of New Nitroimidazole Derivatives as Anti-Helicobacter pylori Agents Against Metronidazole-Resistant Strains

Zahra Bayati, Salimeh Amidi ORCID , Mahnaz Shahabimehr, Masoud Alebouyeh ORCID , Arash Mahboubi ORCID * , Sayyed Abbas Tabatabai ORCID **
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Final Published
28
Jun
2023
Iran J Pharm Res

Solubility of Some Drugs in Aqueous Solutions of Choline Chloride-Based Deep Eutectic Solvent Systems: Experimental Data, Modeling, and the Impact of Solution pH

Samira Zadali Asghar, Raha Kaviani, Ali Shayanfar *
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Final Published
10
Nov
2023
Iran J Pharm Res

Different Modes of Mechanism of Gamma-Mangostin and Alpha-Mangostin to Inhibit Cell Migration of Triple-Negative Breast Cancer Cells Concerning CXCR4 Downregulation and ROS Generation

Sarmoko Sarmoko, Dhania Novitasari, Manami Toriyama, Muhamad Salman Fareza, Nur Amalia Choironi, Hiroshi Itoh, et al.
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Final Published
20
Aug
2023
Iran J Pharm Res

Simultaneous Screening of Six Families of Antibiotic Residues in Milk Samples by Biochip Multi-array Technology

Hassan Yazdanpanah, Mahraz Osouli, Jamshid Salamzadeh, Elham Rashidi, Zakieh Karimi, Leila Beykmohammadi, et al.
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Final Published
07
Sep
2023
Iran J Pharm Res

Ruthenium (II) Complexes Based on Phenanthroline-Tetrazole as Possible Anticancer Agents

Saeid Abaspour, Behzad Soltani * , Hamed Hamishehkar, Moayad Hossaini Sadr
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Final Published
30
Oct
2023
Iran J Pharm Res

The Effects of the Fraction Isolated from Iranian Buthotus shach Scorpion Venom on Synaptic Plasticity, Learning, Memory, and Seizure Susceptibility

Elmira Heidarli, Hossein Vatanpour * , Nafiseh Nasri Nasrabadi ORCID , Maha Soltani, Saeed Tahmasebi, Mehrdad Faizi ORCID **
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Final Published
14
Jul
2023
Iran J Pharm Res

Synthesis and Characterization of a Novel Zinc-Based Metal-Organic Framework Containing Benzoic Acid: A Low-Toxicity Carrier for Drug Delivery

Xiaomei Ye, Mengmeng Xiong, Kangrui Yuan, Wei Liu, Xiaoqun Cai, Yu Yuan, et al.
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Final Published
08
Nov
2023
Iran J Pharm Res

Cost-Utility Analysis of Mirabegron Compared to Solifenacin in the Treatment of Overactive Bladder (OAB) in Iran

Zahra Karimi Majd ORCID , Ghader Mohammadnezhad ORCID , Saeed Taheri ORCID , Nazila Yousefi ORCID *
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Final Published
11
Nov
2023
Iran J Pharm Res

Micronized Progesterone or Dydrogesterone? A Comparative Study on the Effects of Two Forms of Progesterone on Pregnancy Outcomes After Threatened Abortion

Iman Ansari ORCID , Ezzatalsadat Hajiseid Javadi ORCID , Hamideh Pakniat ORCID * , Ali Emami ORCID , Fatemeh Ranjkesh ORCID , Simindokht Molaverdikhani ORCID
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Final Published
11
Nov
2023
Iran J Pharm Res

Antifatigue Effects of the Aqueous Extracts of Myrtle Berries, Apple and Clove: An Animal Study

Akram Alembagheri ORCID , Homa Hajimehdipoor ORCID , Mona Khoramjouy, Somayeh Esmaeili ORCID * , Mehrdad Faizi ORCID **
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Final Published
20
Nov
2023
Iran J Pharm Res

Unveiling Key Biomarkers and Therapeutic Drugs in Polycystic Ovary Syndrome (PCOS) Through Pathway Enrichment Analysis and Hub Gene-miRNA Networks

Roozbeh Heidarzadehpilehrood ORCID , Maryam Pirhoushiaran ORCID , Malina Binti Osman ORCID , King-Hwa Ling ORCID , Habibah Abdul Hamid ORCID *
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Final Published
19
Jul
2023
Iran J Pharm Res

The Analgesic and Anti-inflammatory Effects of Partially Purified Polysaccharide Fractions of Cell-free Medium and Biomass of Spirulina platensis PCST5

Mohammad Dehghanizadeh Baghdadabad, Nima Naderi ORCID , Vahideh Atabaki ORCID , Mohammad Ali Faramarzi ORCID , Maryam Tabarzad ORCID * , Tahereh Hosseinabadi ORCID **
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Final Published
11
Jun
2023
Iran J Pharm Res

The Interaction of SRL-2 Peptide with LRP-1 Receptor and Identification of Breast Cancer Related Biomarkers: An In-silico Approach

Yasamin Davatgaran-Taghipour, Yousof Saeedi-Honar, Roya Salehi ORCID * , Amir Zarebkohan, Vladimir P.Torchilin
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Final Published
17
Apr
2023
Iran J Pharm Res

Design, Synthesis, and Investigation of Cytotoxic Effects of 5-Hydroxyindole-3-Carboxylic Acid and Ester Derivatives as Potential Anti-breast Cancer Agents

Arezo Teymori, Shaya Mokhtari ORCID , Anna Sedaghat, Arash Mahboubi ORCID , Farzad Kobarfard ORCID *
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Final Published
02
Dec
2023
Iran J Pharm Res

Antibacterial Activity and Toxicity of Zinc Oxide Nanoparticles Combined with Supernatants of Lactobacillus spp. Against ESKAPE Bacteria: A Novel Mixture

Somayeh Soleymanzadeh Moghadam ORCID , Reza Hosseini Doust ORCID , Ali Majidpour, Mahdi Adabi, Sara Minaeian ORCID *
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Final Published
06
Dec
2023
Iran J Pharm Res

Performance Evaluation of Biochip Chemiluminescent Immunoassay for Screening Seven Mycotoxins in Wheat Flour Simultaneously

Mahraz Osouli, Hassan Yazdanpanah, Jamshid Salamzadeh, Samira Eslamizad ORCID *
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Final Published
09
Sep
2023
Iran J Pharm Res

Cerasome Versus Liposome: A Comparative Pharmacokinetic Analysis Following Intravenous Administration into Rats

Shima Bahri, Erfan Abdollahizad, Iman Mahlooji, Elham Rezaee ORCID , Zahra Abbasian, Simin Dadashzadeh ORCID *
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Final Published
24
Dec
2023
Iran J Pharm Res

Biological Activity of Novel Pyrrole Derivatives as Antioxidant Agents Against 6-OHDA Induced Neurotoxicity in PC12 Cells

Hanieh Javid, Ebrahim Saeedian Moghadam, Maryam Farahmandfar ORCID , Mahboubeh Manouchehrabadi, Mohsen Amini, Mona Salimi ORCID ** , et al.
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Final Published
08
Dec
2023
Iran J Pharm Res

Screening and Identification of DNA Nanostructure Aptamer Using the SELEX Method for ‎Detection of Epsilon Toxin

Nafiseh Shafiei, Hamideh Mahmoodzadeh Hosseini ORCID * , Jafar Amani ORCID , Seyed Ali Mirhosseini, Hanieh Jafary
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Final Published
12
Dec
2023
Iran J Pharm Res

Design and Evaluation of a Novel Anti-microbial Peptide from Cathelicidin-2: Selectively Active Against Acinetobacter baumannii

Fariba Fathi ORCID , Maryam Ghobeh ORCID , Farshad H Shirazi ORCID , Maryam Tabarzad ORCID *
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Final Published
31
Dec
2023
Iran J Pharm Res

The Mediating Role of Organizational Identification on Sustainable Human Resources Management and Organizational Citizenship Behavior’s Relationship

Shiva Sheikhi ORCID * , Nazila Yousefi ORCID **
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Final Published
23
Aug
2023
Iran J Pharm Res

hTERT Gene Modification Using CRISPR-dCas9-dnmt3a System as a Therapeutic Approach Against Glioma

Farbod Taghavi Rad, Saied Ghorbian ORCID * , Bahar Naghavi Gargari ORCID , Zeinab Shirvani Farsani ORCID , Rasoul Sharifi
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Final Published
10
Apr
2023
Innov J Pharm Res

The Effect of Physical Exercise Pretreatment on Spatial Memory and Learning and Function of Mitochondria in the Brain in Type 2 Diabetic Rats

Homayoon Behmadi ORCID , Fatemeh Samiei ORCID , Marzieh Noruzi ORCID , Zahra Halvaei Khankahdani, Shokoufeh Hassani ORCID , Maryam Mehdizadeh ORCID , et al.
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Final Published
09
Aug
2023
Iran J Pharm Res

Design of a Dual Agonist of Exendin-4 and FGF21 as a Potential Treatment for Type 2 Diabetes Mellitus and Obesity

Changzhen Zhang, Guosheng Gao, Yafeng Li, Jingjing Ying, Jianhui Li, Supei Hu *
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Final Published
30
Oct
2023
Iran J Pharm Res

Evaluating the Effects of Rivastigmine on Decision-Making in Patients with Mild Cognitive Impairment by Cambridge Neuropsychological Test Automated Battery (CANTAB); A Randomized, Double-Blind, Placebo-Controlled Trial

Setayesh Sadeghi, Fatemeh Mohammadian, Mehdi Tehrani-Doost ORCID , Kheirollah Gholami, Niayesh Mohebbi ORCID *
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Final Published
14
Nov
2023
Iran J Pharm Res

Glucose Metabolism in Acute Myeloid Leukemia Cell Line Is Regulated via Combinational PI3K/AKT/mTOR Pathway Inhibitors

Abbas Ranjbar, Mohsen Soltanshahi ORCID , Saeid Taghiloo ORCID * , Hossein Asgarian-Omran ORCID **
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Final Published
27
Aug
2024
Iran J Pharm Res

Developing a Discrete Choice Experiment Instrument for Evaluating Patients’ Preferences in Precision Oncology

Zahra Karimi Majd ORCID , Nazila Yousefi ORCID , Mohammad Peikanpour ORCID , Mohammad Sistanizad ORCID , Ghader Mohammadnezhad ORCID , Behniya Azadmehr, et al.
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Final Published
14
Oct
2023
Iran J Pharm Res

The Efficacy and Safety of Propranolol in Treating Infantile Hemangioma: A Prospective Study

Mohammad Reza Khalilian ORCID , Fariba Esmaeili ORCID , Mohamad Reza Vahidi ORCID , Mohsen Rouzrokh ORCID , Elham Abdoulahzadeh ORCID , Hadi Pashapour ORCID , et al.
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Final Published
07
Jan
2024
Iran J Pharm Res

Synthesis and Biological Evaluation of Novel Thiadiazole Derivatives as Antiplatelet Agents

Mahsima Khakpash, Marjan Esfahanizadeh, Mohammad Mahboubi-Rabbani, Salimeh Amidi ORCID * , Farzad Kobarfard ORCID
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Final Published
31
Oct
2023
Iran J Pharm Res

Preparation and in Vitro Property Research of Cholic Acid Nanoparticles with Dual-functions of Hemostasis and Antibacterial

Jin Ma, Cong Wang, Tieying Yin, Yang Jiang, Wanjun Yu, Xiaoyu Zhang, et al.
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Final Published
29
Jan
2024
Iran J Pharm Res

Effect of Solanum melongena on Components and Kidney Damage of Fructose-Induced Metabolic Syndrome in Rats

Elizabeth Guzmán Hernández ORCID * , Maria del Rosario González Valle, José Carmelo Benítez Flores, Maria Eugenia Garian Aguilar, Rubén San Miguel Chávez, Maria Dolores Hernández Martínez, et al.
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Final Published
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