Sign in

Iranian Journal of Pharmaceutical Research

e-ISSN 1726-6890
p-ISSN 1735-0328
Authors GuideSubmit manuscript

Volume 24, Issue 1

111 articlesJan - DecVol. 24Issue 1XML
8
Feb
2026
Paclitaxel- and Sirolimus-Coated Drug-Coated Balloons versus Drug-Eluting Stents in Acute Myocardial Infarction: A Comprehensive Systematic Review and Meta-Analysis
Systematic Review

Paclitaxel- and Sirolimus-Coated Drug-Coated Balloons versus Drug-Eluting Stents in Acute Myocardial Infarction: A Comprehensive Systematic Review and Meta-Analysis

Zhengmin Zhang,
Gang Yu,
Rong Guo*
PDFFinal Published
20
Jan
2026
Tehranolide Attenuates Lipid Accumulation in Steatotic HepG2 Cells via cAMP/AMPK/SIRT1-Mediated Autophagy Activation
Research Article

Tehranolide Attenuates Lipid Accumulation in Steatotic HepG2 Cells via cAMP/AMPK/SIRT1-Mediated Autophagy Activation

Shima LorestaniORCID,
Shahla Mohammad GanjiORCID,
Shokoofe NooriORCID*
PDFFinal Published
4
Jan
2026
MEK1/2 Inhibitor (U0126) and PI3K Inhibitor (LY294002) Suppress Herpes Simplex Virus Type 1 Replication by Targeting MAPK/ERK1/2 and PI3K/AKT Signaling Pathways: Implications for Oral Health and Translational Control of Orolabial HSV-1 Infection
Research Article

MEK1/2 Inhibitor (U0126) and PI3K Inhibitor (LY294002) Suppress Herpes Simplex Virus Type 1 Replication by Targeting MAPK/ERK1/2 and PI3K/AKT Signaling Pathways: Implications for Oral Health and Translational Control of Orolabial HSV-1 Infection

Wei Meng,
Zahra Zahid PirachaORCID,
Umar SaeedORCID,
Dilber Uzun Ozsahin,
Ilker Ozsahin,
Yongwei Tao*
,et al.
PDFFinal Published
31
Dec
2025
Quercetin-Loaded Avocado Oil Nanoemulsion Reverses High-fat and High-carbohydrate Diet-Induced Testicular Dysfunction: Role of Oxidative Stress and NPY Signaling in a Randomized Trial
Research Article

Quercetin-Loaded Avocado Oil Nanoemulsion Reverses High-fat and High-carbohydrate Diet-Induced Testicular Dysfunction: Role of Oxidative Stress and NPY Signaling in a Randomized Trial

Hamidreza Mazangi,
Negar PanahiORCID*,
Saeed HesarakiORCID,
Shahabeddin Safi
PDFFinal Published
28
Dec
2025
The Role of GRP78/ATF6/IRE1 and Caspase-12 Signaling Pathways in the Protective Effects of n-Hexane Oil Extract of Black Soldier Flies’ Larvae (Hermetia illucens) Against Aflatoxin-Induced Hepatotoxicity in Rats
Research Article

The Role of GRP78/ATF6/IRE1 and Caspase-12 Signaling Pathways in the Protective Effects of n-Hexane Oil Extract of Black Soldier Flies’ Larvae (Hermetia illucens) Against Aflatoxin-Induced Hepatotoxicity in Rats

Fateme HeidariORCID,
Tahereh Zarei Taher,
Yalda Arast*
PDFFinal Published
28
Dec
2025
Erratum: Secondary Autoimmune Dermatological Disorders Induced by Multiple Sclerosis Biological Immunotherapy Agents: A Systematic Review of Case Reports [IJ Pharm Res. 2025; 24 (1): e166426]
Correction

Erratum: Secondary Autoimmune Dermatological Disorders Induced by Multiple Sclerosis Biological Immunotherapy Agents: A Systematic Review of Case Reports [IJ Pharm Res. 2025; 24 (1): e166426]

Mohammad Ali Sahraian,
Shahaboddin Emami,
Sara Ataei,
Fahime Nasr Esfahani,
Nasibeh GhalandariORCID*
PDFFinal Published
23
Dec
2025
Evaluating the Impact of Strategic Alignment on Performance Components of Iranian Pharmaceutical Companies Using Machine Learning Techniques
Research Article

Evaluating the Impact of Strategic Alignment on Performance Components of Iranian Pharmaceutical Companies Using Machine Learning Techniques

Simin SadeghiORCID*,
Mahdi Mohammadzadeh**
PDFFinal Published
22
Dec
2025
In Silico and in vitro Characterization of Lactobacillus acidophilus Bacteriocins as ROR-1-Targeted Therapeutics in Breast Cancer
Research Article

In Silico and in vitro Characterization of Lactobacillus acidophilus Bacteriocins as ROR-1-Targeted Therapeutics in Breast Cancer

Sara SoheiliORCID,
Shekufe Rezghi BarezORCID,
Seyed Davar SiadatORCID,
Seyed Hossein HejaziORCID,
Hamid AbtahiORCID*
PDFFinal Published
22
Dec
2025
Resilience in Urban Pharmacies: A Mixed-Methods Model for Performance and Patient Satisfaction During Crises
Research Article

Resilience in Urban Pharmacies: A Mixed-Methods Model for Performance and Patient Satisfaction During Crises

Javad Shamsaee*,
Farzad PeiravianORCID,
Samane JahanabadiORCID,
Mohammad PeikanpourORCID**
PDFFinal Published
21
Dec
2025
Mitotherapy and the Possibility of Energetic Rescue in Evolving Brain Death
Letter

Mitotherapy and the Possibility of Energetic Rescue in Evolving Brain Death

Ali DabbaghORCID*,
Jalal PourahmadORCID,
Amir Farrokhian
PDFFinal Published
17
Dec
2025
Daphnetin Ameliorates the Amyloid β-Induced Alzheimer Disease via Restoring Potassium-Chloride Co-Transporter 2 (KCC2) Ion Channel Functions in Mice
Research Article

Daphnetin Ameliorates the Amyloid β-Induced Alzheimer Disease via Restoring Potassium-Chloride Co-Transporter 2 (KCC2) Ion Channel Functions in Mice

Yanyan ZhouORCID,
Fang ZhouORCID,
Hongbin LiORCID*
PDFFinal Published
14
Dec
2025
Short-term Antihyperglycemic and Weight Modulation Effects of Leuenbergeria bleo (Kunth) Lodé: Phytochemical Screening and in vivo Assessment in an Alloxan-Induced Diabetic Rat Model
Research Article

Short-term Antihyperglycemic and Weight Modulation Effects of Leuenbergeria bleo (Kunth) Lodé: Phytochemical Screening and in vivo Assessment in an Alloxan-Induced Diabetic Rat Model

Sheryar AfzalORCID*,
Velaga Venkata Sathya Sai AppalarajuORCID,
Ali AttiqORCID,
Iram MalikORCID,
Ibrahim AlbokhadaimORCID,
Sameer M AlhojailyORCID
,et al.
PDFFinal Published
13
Dec
2025
Biomolecular Insights Into the Antifungal Activity of Allium Species Constituents: From Mechanisms to Applications
Systematic Review

Biomolecular Insights Into the Antifungal Activity of Allium Species Constituents: From Mechanisms to Applications

Saeid EslamiORCID,
Behzad ZolfaghariORCID,
Masoud Sadeghi Dinani,
Mustafa GhanadianORCID*
PDFFinal Published
8
Dec
2025
Pin1 as a Central Modulator of Wnt/β-Catenin Signaling in Pulmonary Fibrosis: Interplay with EBV-LMP1 and Therapeutic Implications
Research Article

Pin1 as a Central Modulator of Wnt/β-Catenin Signaling in Pulmonary Fibrosis: Interplay with EBV-LMP1 and Therapeutic Implications

Xiaodan Jiao,
Jin Yingli,
Yanchao Liu,
Hong Jiang Yan,
Pei Wang,
Yadong Yuan*
PDFFinal Published
7
Dec
2025
Design and Optimization of Chitosan/Montmorillonite Nanoparticle for Sustained Vancomycin Delivery in Peri-implantitis
Research Article

Design and Optimization of Chitosan/Montmorillonite Nanoparticle for Sustained Vancomycin Delivery in Peri-implantitis

Shima Esmailzadeh,
Taherehsadat Jafarzadeh*,
Mohammad Moazen
PDFFinal Published
6
Dec
2025
Protective Effects of Berberine-Loaded Black Seed (Nigella sativa L.) Oil Nanoemulsion in the Atherosclerotic Mouse Model
Research Article

Protective Effects of Berberine-Loaded Black Seed (Nigella sativa L.) Oil Nanoemulsion in the Atherosclerotic Mouse Model

Nasim Darjani,
Negar PanahiORCID*,
Pejman Mortazavi,
Mohammad Kazem KoohiORCID
PDFFinal Published
2
Dec
2025
Ellagic Acid Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis Through the Modulation of the SIRT1/p53 Pathway in Streptozotocin-Induced Diabetic Rats
Research Article

Ellagic Acid Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis Through the Modulation of the SIRT1/p53 Pathway in Streptozotocin-Induced Diabetic Rats

Qingmei Wang,
Xuanguo Zhang,
Li Xi*
PDFFinal Published
2
Dec
2025
Secondary Autoimmune Dermatological Disorders Induced by Multiple Sclerosis Biological Immunotherapy Agents: A Systematic Review of Case Reports
Systematic Review

Secondary Autoimmune Dermatological Disorders Induced by Multiple Sclerosis Biological Immunotherapy Agents: A Systematic Review of Case Reports

Mohammad Ali Sahraian,
Shahboddin Emami,
Sara Ataei,
Fahime Nasr Esfahani,
Nasibeh GhalandariORCID*
PDFFinal Published
30
Nov
2025
Phenolic Compounds and Flavonoids in Various Extracts of Ferula tadshikorum and Ferula sumbul Grown in vitro Conditions
Research Article

Phenolic Compounds and Flavonoids in Various Extracts of Ferula tadshikorum and Ferula sumbul Grown in vitro Conditions

Dilafruz Jamalova Ne'matilla QiziORCID*,
Gulsauir Kurbaniyazova Tanirbergen Kizi,
Imene Caliscan Tatar,
Atoeva Rukhsora Odilovna,
Nargiza Achilova Tuxtanazarovna,
Azima Saitova Kaljanovna
,et al.
PDFFinal Published
30
Nov
2025
Biosynthesis and Characterization of Selenium Nanoparticles by Kocuria Strain Bm3: Evaluating Their Synergistic Antimicrobial Activity with Chlorellavulgaris Crude Extract Against Multidrug-Resistant Bacteria
Research Article

Biosynthesis and Characterization of Selenium Nanoparticles by Kocuria Strain Bm3: Evaluating Their Synergistic Antimicrobial Activity with Chlorellavulgaris Crude Extract Against Multidrug-Resistant Bacteria

Hamid Babavalian*,
Fatemeh Shakeri,
Atefeh Safarpour,
Iman Hassankhani,
Zohre Nasrollahzadeh,
Mohammad Ali AmoozegarORCID
PDFFinal Published
27
Nov
2025
In vitro Multi-targeted Anti-cancer Effects of Bavachinin in Papillary Thyroid Carcinoma Cell Line: Dual Pathway Inhibition and Cytokine Downregulation
Research Article

In vitro Multi-targeted Anti-cancer Effects of Bavachinin in Papillary Thyroid Carcinoma Cell Line: Dual Pathway Inhibition and Cytokine Downregulation

Gang Duan,
Zahra Zahid PirachaORCID,
Umar SaeedORCID,
Yanrong Tian*
PDFFinal Published
23
Nov
2025
Oncogenic Function of miR-182-5p Versus Tumor-Suppressive Activities of miR-203, miR-150-5p, and miR-139-5p via Target Gene Regulation in Colon Cancer Metastasis
Research Article

Oncogenic Function of miR-182-5p Versus Tumor-Suppressive Activities of miR-203, miR-150-5p, and miR-139-5p via Target Gene Regulation in Colon Cancer Metastasis

Sheryar AfzalORCID,
Ali AttiqORCID*
PDFFinal Published
18
Nov
2025
Effects of Acacetin on the Pharmacokinetics of Diazepam in vivo and in vitro
Research Article

Effects of Acacetin on the Pharmacokinetics of Diazepam in vivo and in vitro

Ailian Hua,
Li Wang,
Yao Zhu,
Quan Zhou,
Abdullah Al Mamun,
Shuanghu Wang
,et al.
PDFFinal Published
17
Nov
2025
Quercetin Inhibits Gastric Cancer Progression via Suppression of HOTAIR/mir-217/GPC5 Axis
Research Article

Quercetin Inhibits Gastric Cancer Progression via Suppression of HOTAIR/mir-217/GPC5 Axis

Zhuqing QiuORCID,
Chonglei QuORCID,
Xiaoying WuORCID*
PDFFinal Published
16
Nov
2025
Design, Expression, and Binding Interactions Study of the Recombinant Engineered IL-6R
Research Article

Design, Expression, and Binding Interactions Study of the Recombinant Engineered IL-6R

Elham Mehdizadeh Marzenaki,
Mojgan BandehpourORCID*,
Adel Haghighi,
Sepideh Ghani,
Maryam TabarzadORCID,
Mahya Nasrollahi
,et al.
PDFFinal Published
15
Nov
2025
Traditional Chinese Medicine Approach to Renal Cell Carcinoma: Jing-Si Herbal Tea Triggers Apoptosis and Ferroptosis in HK-2 Cells
Letter

Traditional Chinese Medicine Approach to Renal Cell Carcinoma: Jing-Si Herbal Tea Triggers Apoptosis and Ferroptosis in HK-2 Cells

Yao-Chou Tsai,
Chung-Che Tsai,
Jin‑Yin Chang,
Hsu-Hung Chang*,
Chan-Yen KuoORCID**
PDFFinal Published
15
Nov
2025
Tanshinone ⅡA Inhibits Alveolar Macrophage Polarization, Inflammation and Mitochondrial Damage by Regulating the PAPR-1 Signaling Pathway
Research Article

Tanshinone ⅡA Inhibits Alveolar Macrophage Polarization, Inflammation and Mitochondrial Damage by Regulating the PAPR-1 Signaling Pathway

Na ZhangORCID,
Xinjia Yang,
Jiefei LiangORCID,
Chunyan Zhu,
Guohua Shen,
Chao LuoORCID*
,et al.
PDFFinal Published
11
Nov
2025
Biological Activities of Alkaloid Fraction of Fritillaria karelinii (Fisch. ex D. Don)
Research Article

Biological Activities of Alkaloid Fraction of Fritillaria karelinii (Fisch. ex D. Don)

Ardak Omarbekova,
Sebastian John Adams,
Mamdouh Nabil Samy,
Ubaidilla Datkhayev,
Lashyn Kiyekbayeva*,
Elmira Kapsalyamova
,et al.
PDFFinal Published
8
Nov
2025
Therapeutic Applications and Target Strategies of Antibody-Drug Conjugates in Ovarian Cancer
Review Article

Therapeutic Applications and Target Strategies of Antibody-Drug Conjugates in Ovarian Cancer

Qiming Liu,
Runji Zhou,
Taiqi He,
Yonghong Zhao,
Mei Yang*
PDFFinal Published
4
Nov
2025
Phenolic Compounds from Diarthron iranica: Enzymatic and in Silico Insights Into α-Amylase Inhibitory Activity
Research Article

Phenolic Compounds from Diarthron iranica: Enzymatic and in Silico Insights Into α-Amylase Inhibitory Activity

Zeinab Yazdiniapour,
Reza Gashavi,
Tohid Khodabande,
Hossein BiganehORCID,
Morteza SadeghiORCID,
Mehran Miroliaei
,et al.
PDFFinal Published
4
Nov
2025
Chinese Herbal Medicine in the Treatment of Chronic Kidney Disease: A Narrative Review of Mechanisms and Therapeutic Potential
Review Article

Chinese Herbal Medicine in the Treatment of Chronic Kidney Disease: A Narrative Review of Mechanisms and Therapeutic Potential

Yao-Chou Tsai,
Chung-Che Tsai,
Ya-Hsuan Lin,
Hsu-Hung Chang*,
Chan-Yen KuoORCID**
PDFFinal Published
4
Nov
2025
Capparis spinosa Attenuates Hepatic Inflammation and Fibrosis by Suppressing Inflammatory Cytokines in a Wistar Rat Model of Nonalcoholic Steatohepatitis
Research Article

Capparis spinosa Attenuates Hepatic Inflammation and Fibrosis by Suppressing Inflammatory Cytokines in a Wistar Rat Model of Nonalcoholic Steatohepatitis

Rasoul AkbariORCID,
Tahereh Behdarvand,
Hamid Yaghooti,
Mohammad Taha Jalali,
Narges MohammadtaghvaeiORCID*
PDFFinal Published
29
Oct
2025
Evaluating the Effects of Crocus sativus L. Herbal Product on Chronic Fatigue Syndrome in Patients with Chronic Obstructive Pulmonary Disease: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Research Article

Evaluating the Effects of Crocus sativus L. Herbal Product on Chronic Fatigue Syndrome in Patients with Chronic Obstructive Pulmonary Disease: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Farzaneh DastanORCID,
Jamshid SalamzadehORCID,
Jalal HeshmatniaORCID,
Reza MahmoudianORCID*
PDFFinal Published
24
Oct
2025
Dual Inhibitors of c-MET and EGFR in Triple Negative Breast Cancer: Pharmacophore Modeling and Molecular Dynamics Based in Silico Drug Repositioning
Research Article

Dual Inhibitors of c-MET and EGFR in Triple Negative Breast Cancer: Pharmacophore Modeling and Molecular Dynamics Based in Silico Drug Repositioning

Shadi Abkhiz,
Parastoo Tarighi*,
Homa Azizian**
PDFFinal Published
24
Oct
2025
Combined Omega-3 Fatty Acid and Folic Acid Supplementation Reduces Neonatal Hypoxic-Ischemic Brain Injury via Anti-inflammatory and Anti-apoptotic Mechanisms
Research Article

Combined Omega-3 Fatty Acid and Folic Acid Supplementation Reduces Neonatal Hypoxic-Ischemic Brain Injury via Anti-inflammatory and Anti-apoptotic Mechanisms

Wendong Sun*,
Tanu Ojha,
Vinod Kumar Verma,
Siddhartha Kumar Mishra**
PDFFinal Published
20
Oct
2025
Evaluating the Cardioprotective Effects of Melatonin in Non-metastatic Breast Cancer Patients Receiving Doxorubicin Plus Cyclophosphamide: A Triple-Blind, Placebo-Controlled Randomized Controlled Trial
Research Article

Evaluating the Cardioprotective Effects of Melatonin in Non-metastatic Breast Cancer Patients Receiving Doxorubicin Plus Cyclophosphamide: A Triple-Blind, Placebo-Controlled Randomized Controlled Trial

Seyyed Mohammad MousaviniaORCID,
Farnoosh LartiORCID,
Hossein Ranjbar,
Marzieh Lashkari,
Kamran RoudiniORCID,
Amir Hossein EmamiORCID
,et al.
PDFFinal Published
18
Oct
2025
Research Progress on the Diagnosis and Treatment of Intestinal Fibrosis in Crohn's Disease with Traditional Chinese and Western Medicine
Systematic Review

Research Progress on the Diagnosis and Treatment of Intestinal Fibrosis in Crohn's Disease with Traditional Chinese and Western Medicine

Qili Xiao,
Delong Mo,
Gang Liu,
Yuting Xu,
Yan Chen*,
Chuanjian Lu**
PDFFinal Published
15
Oct
2025
Exploring the Role of Amitriptyline in Modulating Gag Reflex Sensitivity
Research Article

Exploring the Role of Amitriptyline in Modulating Gag Reflex Sensitivity

Mehdi Modiri,
Reyhaneh ShoorgashtiORCID,
Farnaz Haji Fattahi,
Simin LesanORCID*
PDFFinal Published
15
Oct
2025
Re-evaluating the Safety of Zolpidem: Risks and Clinical Implications
Letter

Re-evaluating the Safety of Zolpidem: Risks and Clinical Implications

Mohammad BabaeianORCID*,
Ladan AyazkhooORCID
PDFFinal Published
12
Oct
2025
Isoliquiritigenin in Breast Cancer: A Systematic Review of Its Preventive and Anti-metastatic Mechanisms
Systematic Review

Isoliquiritigenin in Breast Cancer: A Systematic Review of Its Preventive and Anti-metastatic Mechanisms

Yuan Xue,
Mingjun Wang*
PDFFinal Published
10
Oct
2025
Effect of Gabapentin on Heart Rate Variability in Patients with Painful Diabetic Peripheral Neuropathy: A Double-blinded Randomized Controlled Trial
Research Article

Effect of Gabapentin on Heart Rate Variability in Patients with Painful Diabetic Peripheral Neuropathy: A Double-blinded Randomized Controlled Trial

Farnaz Ahmadi,
Maryam VasheghaniORCID*,
Mehdi Moradi,
Jalal Poorolajal,
Fatemeh Zeraati,
Hamidreza Dezfouli
,et al.
PDFFinal Published
1
Oct
2025
Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes
Research Article

Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes

Jae Ho Lee,
Sungkwan An,
Seokmuk Park*,
Seunghee Bae**
PDFFinal Published
1
Oct
2025
Unveiling the Bioactive Potential of Allium colchicifolium Boiss Bulb Flavonoids: Anti-cancer Activities, and Computational Exploration of Anti-angiogenic Mechanisms
Research Article

Unveiling the Bioactive Potential of Allium colchicifolium Boiss Bulb Flavonoids: Anti-cancer Activities, and Computational Exploration of Anti-angiogenic Mechanisms

Mohammad Bagher MajnooniORCID,
Mustafa GhanadianORCID*,
Kamran MansouriORCID,
Golam Reza BahramiORCID,
Mahdi MojarrabORCID**
PDFFinal Published
30
Sep
2025
Development and Assessment of a Decentralization Framework in Iran Pharmaceutical Regulatory Systems Based on Good Governance Indicators
Research Article

Development and Assessment of a Decentralization Framework in Iran Pharmaceutical Regulatory Systems Based on Good Governance Indicators

Sajjad EsmaeiliORCID,
Mohammad PeikanpourORCID,
Farzad PeiravianORCID*
PDFFinal Published
24
Sep
2025
Exploring the Bioactive Compounds of Haematococcus pluvialis for Resistant-Antimicrobial Applications in Diabetic Foot Ulcers Control
Research Article

Exploring the Bioactive Compounds of Haematococcus pluvialis for Resistant-Antimicrobial Applications in Diabetic Foot Ulcers Control

Fateme MirzajaniORCID*,
Narges Parniaei,
Faeze Mirzajani,
Arefe Ghaderi
PDFFinal Published
21
Sep
2025
Therapeutic Investigation of Zingerone Against Pentylenetetrazole-Induced Kindled Seizures in Mice
Research Article

Therapeutic Investigation of Zingerone Against Pentylenetetrazole-Induced Kindled Seizures in Mice

Xiaocui TianORCID,
Xiaoke Xu*
PDFFinal Published
16
Sep
2025
Mitigation of Cerebral Ischemia-Reperfusion Injury in Rat by Phellopterin via Antioxidant and Anti-inflammatory Mechanisms
Research Article

Mitigation of Cerebral Ischemia-Reperfusion Injury in Rat by Phellopterin via Antioxidant and Anti-inflammatory Mechanisms

Huici Wang*,
Huan Wang
PDFFinal Published
15
Sep
2025
Multi-omics Identify the Role of FGF7 Pathway in Diabetic Foot Ulcers
Research Article

Multi-omics Identify the Role of FGF7 Pathway in Diabetic Foot Ulcers

Wenkang Luan,
Shujun Fan,
Dongwen Jiang,
Leren He*
PDFFinal Published
13
Sep
2025
In Silico Analysis of Tat Exons to Increase the Efficacy of a Nef-Tat-based HIV-1 Vaccine Candidate
Research Article

In Silico Analysis of Tat Exons to Increase the Efficacy of a Nef-Tat-based HIV-1 Vaccine Candidate

Leila Sadeghi,
Fatemeh Heidarnejad,
Azam Bolhassani*,
Elham Mohit**,
Parisa Moradi Pordanjani
PDFFinal Published
13
Sep
2025
Enhanced Hyaluronic Acid Production in Streptococcus equi subsp. Streptococcuszooepidemicus Through Strain Mutagenesis and Optimized Purification
Research Article

Enhanced Hyaluronic Acid Production in Streptococcus equi subsp. Streptococcuszooepidemicus Through Strain Mutagenesis and Optimized Purification

Kamand Hedayat,
Delaram DoroudORCID*,
Naser Mohamadpour Dounighi,
Mohammad Ali Shokrgozar,
Maryam Shahali,
Mohammad Hassan Houshdar Tehrani
PDFFinal Published
7
Sep
2025
A Review of Medicinal Plants Used for Uterine Disorders in Makhzan al-Adwiyyah: Insights from Persian Medicine
Review Article

A Review of Medicinal Plants Used for Uterine Disorders in Makhzan al-Adwiyyah: Insights from Persian Medicine

Fatemeh RabizadehORCID*
PDFFinal Published
6
Sep
2025
IDO Inhibition by 1-Methyltryptophan: Unlocking New Paths to Treat Ovarian Dysfunction and Hormonal Imbalance in PCOS
Research Article

IDO Inhibition by 1-Methyltryptophan: Unlocking New Paths to Treat Ovarian Dysfunction and Hormonal Imbalance in PCOS

Hediyeh Gheymoumi,
Sevda ShayestehORCID*,
Marziyeh Amiri-Andebilib,
Naim Gheymoumi,
Fatemeh Sharifi,
Ahmad Reza DehpourORCID
PDFFinal Published
3
Sep
2025
Integrating Network Pharmacology and Experimental Validation to Identifying Key Herbal Components and Targets for Liver Cancer
Research Article

Integrating Network Pharmacology and Experimental Validation to Identifying Key Herbal Components and Targets for Liver Cancer

Fang Wang,
Shenghao Li,
Xiling Liu,
Yi Xu,
Huimin Yan*
PDFFinal Published
2
Sep
2025
Neuroprotection by Resveratrol in Chronic Cerebral Hypoperfusion: A Study on Synaptogenesis Enhancement and Apoptosis Inhibition
Research Article

Neuroprotection by Resveratrol in Chronic Cerebral Hypoperfusion: A Study on Synaptogenesis Enhancement and Apoptosis Inhibition

Abdollah Kasaei,
Mohsen ForouzanfarORCID*,
Mojtaba JafariniaORCID
PDFFinal Published
2
Sep
2025
Vancomycin Insights: An Update on Mechanism, Activity, Toxicity, Resistance, and Novel Drug Delivery Systems
Review Article

Vancomycin Insights: An Update on Mechanism, Activity, Toxicity, Resistance, and Novel Drug Delivery Systems

Maryam TabarzadORCID,
Maryam TorshabiORCID,
Mohadeseh HeidariORCID,
Azadeh HaeriORCID*,
Seyedeh Maryam Mortazavi**
PDFFinal Published
31
Aug
2025
Design and Pharmaceutical Evaluation of Piper nigrum Oil Nanoemulsion by Phase Diagram for Topical Analgesic Applications
Research Article

Design and Pharmaceutical Evaluation of Piper nigrum Oil Nanoemulsion by Phase Diagram for Topical Analgesic Applications

Shayan Fallah,
Hajar Ashrafi,
Mohammad Ali Farboodniay Jahromi*,
Mohammad Mehdi ZarshenasORCID**
PDFFinal Published
30
Aug
2025
Evaluation of Anticarcinogenic and Cytotoxic Effects of COX-2 Specific Inhibitors on an Animal Model of Hepatocellular Carcinoma Using Isolated Mitochondria
Research Article

Evaluation of Anticarcinogenic and Cytotoxic Effects of COX-2 Specific Inhibitors on an Animal Model of Hepatocellular Carcinoma Using Isolated Mitochondria

Alireza Mahmudi,
Enayatollah Seydi,
Nahid Ahmadi,
Zhaleh Mohsenifar,
Mahsa Azami Movahed,
Afshin ZarghiORCID*
,et al.
PDFFinal Published
26
Aug
2025
Anti-proliferative Activity and Apoptosis Induction of Extracts and Fractions of Stachys lavandulifolia on Lung (H1299), Ovarian (A2780) and Breast (MCF-7) Human Cancer Cell Lines
Research Article

Anti-proliferative Activity and Apoptosis Induction of Extracts and Fractions of Stachys lavandulifolia on Lung (H1299), Ovarian (A2780) and Breast (MCF-7) Human Cancer Cell Lines

Leila HosseinzadehORCID,
Pouria HajmomeniORCID,
Mohadeseh SalehiORCID,
Masuod ModarresiORCID*,
Fereshteh JalilianORCID**
PDFFinal Published
25
Aug
2025
Preparation and in vitro Immunoreactivity of Rosa rugosa Polysaccharide Liposomes
Research Article

Preparation and in vitro Immunoreactivity of Rosa rugosa Polysaccharide Liposomes

Qinfang He,
Riqing Cheng,
Jiahao Shi,
Ta Na,
Qiherima WangORCID*,
Sarangowa OchirORCID**
PDFFinal Published
19
Aug
2025
The Impact of Black Walnut (Juglans nigra) Oil on Male Wistar Rats Suffering from Methimazole-Induced Hypothyroidism
Research Article

The Impact of Black Walnut (Juglans nigra) Oil on Male Wistar Rats Suffering from Methimazole-Induced Hypothyroidism

Sedighe Morakabati,
Alireza MotavalizadehkakhkyORCID*,
Amirhossein Esmaeili,
Jamshid MehrzadORCID,
Rahele Zhiani
PDFFinal Published
16
Aug
2025
In-vitro Assessment of the Proliferation and Apoptosis of Thyroid Cancer Cells Using Valproic Acid and Retinoic Acid Alone and in Combination with Etoposide and Epirubicin
Research Article

In-vitro Assessment of the Proliferation and Apoptosis of Thyroid Cancer Cells Using Valproic Acid and Retinoic Acid Alone and in Combination with Etoposide and Epirubicin

Ramin Ebrahimi Kiasari,
Ghazaleh Ghavami,
Soroush SardariORCID*
PDFFinal Published
16
Aug
2025
Elucidating the Inhibitory Potential of Statins Against Oncogenic c-Met Tyrosine Kinase Through Computational and Cell-based Studies
Research Article

Elucidating the Inhibitory Potential of Statins Against Oncogenic c-Met Tyrosine Kinase Through Computational and Cell-based Studies

Elham Ahmad Alizadeh,
Leila Karami,
Fahimeh Ghasemi,
Amir Shadboorestan,
Mohammad Reza Torabi,
Vahideh Montazeri
,et al.
PDFFinal Published
12
Aug
2025
Expression Modulation of Immune Inhibitory Molecules by Small Molecule Inhibitor Drugs in Leukemic Cells of Chronic Lymphocytic Leukemia
Research Article

Expression Modulation of Immune Inhibitory Molecules by Small Molecule Inhibitor Drugs in Leukemic Cells of Chronic Lymphocytic Leukemia

Fatemeh Mousavi-MirkalaeiORCID,
Saeid TaghilooORCID,
Maryam Alizadeh-ForoutanORCID,
Ehsan ZaboliORCID,
Mohammad Eslami-JouybariORCID,
Ramin ShekarrizORCID
,et al.
PDFFinal Published
11
Aug
2025
Inhibition of Inflammatory Signals “HMGB1, NLRP3, TNF-α, IL-1β” and Oxidative Stress in Diclofenac-Induced Hepatotoxicity in Rats Using Hydroalcoholic Extract of Dracocephalum kotschyi
Research Article

Inhibition of Inflammatory Signals “HMGB1, NLRP3, TNF-α, IL-1β” and Oxidative Stress in Diclofenac-Induced Hepatotoxicity in Rats Using Hydroalcoholic Extract of Dracocephalum kotschyi

Maryam Karimi-DehkordiORCID,
Firoozeh SaghaeiORCID*,
Erfan HoseiniORCID
PDFFinal Published
5
Aug
2025
Low-Dose Celastrol Modulates IL-6 Secretion to Overcome Resistance to Sorafenib in Hepatocellular Carcinoma Cells
Research Article

Low-Dose Celastrol Modulates IL-6 Secretion to Overcome Resistance to Sorafenib in Hepatocellular Carcinoma Cells

Rui ZhangORCID*,
Lingchun Kong,
Hezhao Zhang,
Anhong Zhang,
Zhiyong Shi,
Pei WeiORCID**
PDFFinal Published
3
Aug
2025
Assessing the Challenges of Managing Pharmacy Services in Public Hospitals in Erbil City
Research Article

Assessing the Challenges of Managing Pharmacy Services in Public Hospitals in Erbil City

Sanar Ilias KamalORCID*,
Kemal M SurjiORCID
PDFFinal Published
28
Jul
2025
Chronic Pseudomonas aeruginosa Pneumonia Triggers Inflammation-Driven Oncogenic Signaling in Juvenile Mice: Implications for Pharmacological Intervention
Research Article

Chronic Pseudomonas aeruginosa Pneumonia Triggers Inflammation-Driven Oncogenic Signaling in Juvenile Mice: Implications for Pharmacological Intervention

Jing Zhang,
Zahra Zahid PirachaORCID,
Umar SaeedORCID,
Dilber Uzun Ozsahin,
Muhammad Waseem,
Yale Zhang*
PDFFinal Published
27
Jul
2025
Evaluation of the Rational Use of Broad-Spectrum Antibiotics According to Regulatory Guidelines in Hospitalized Patients: A Descriptive Study
Research Article

Evaluation of the Rational Use of Broad-Spectrum Antibiotics According to Regulatory Guidelines in Hospitalized Patients: A Descriptive Study

Alireza Kananinambani,
Majid Shohrati*,
Mahdi Bagheri,
Bita Najafian
PDFFinal Published
26
Jul
2025
Schisanhenol Alleviates Mycophenolic Acid-Induced Intestinal Epithelial Cell Barrier Damage by Activating the Nrf2/HO-1 Signaling Pathway
Research Article

Schisanhenol Alleviates Mycophenolic Acid-Induced Intestinal Epithelial Cell Barrier Damage by Activating the Nrf2/HO-1 Signaling Pathway

Yiyun Deng,
Jiawang Fan,
Chunlan Yang,
Yan Huang,
Qingrong Xia,
Jun Liang
,et al.
PDFFinal Published
21
Jul
2025
Cancer-Associated Fibroblasts Enhance Oxaliplatin Resistance in Colorectal Cancer Cells via Paracrine IL-6: An In Vitro Study
Brief Report

Cancer-Associated Fibroblasts Enhance Oxaliplatin Resistance in Colorectal Cancer Cells via Paracrine IL-6: An In Vitro Study

Jiahui Wang,
Yanxin Lu,
Zhiyong WangORCID*,
Pei WeiORCID**
PDFFinal Published
16
Jul
2025
Effect of Diamorphine on Spatial Learning and Memory and Mitochondrial Function of Male Rat Brain
Research Article

Effect of Diamorphine on Spatial Learning and Memory and Mitochondrial Function of Male Rat Brain

Ainaz Moshtagh,
Maryam Mehdizadeh,
Ghodsieh Hosseinifakhr,
Alireza Foroumadi,
Maryam Baeeri,
Shokoufeh Hassani
,et al.
PDFFinal Published
13
Jul
2025
Anti-tumor Effects of Hedyotis diffusa Willd on Cervical Cancer: Inhibition of Proliferation, Migration, and Induction of Apoptosis
Research Article

Anti-tumor Effects of Hedyotis diffusa Willd on Cervical Cancer: Inhibition of Proliferation, Migration, and Induction of Apoptosis

Siyu Yang,
Lizhu Zeng,
Caiyun Deng,
Xianglian Tian,
Wenkui Sun,
Chengjie Ji*
,et al.
PDFFinal Published
8
Jul
2025
Role of Arctium lappa L. Root (Burdock) Extract in CFA-induced Arthritis Rat Model: Impact on Antioxidant Activity and Inflammation
Research Article

Role of Arctium lappa L. Root (Burdock) Extract in CFA-induced Arthritis Rat Model: Impact on Antioxidant Activity and Inflammation

Mohammad Hosein FarzaeiORCID,
Arezoo Moini JazaniORCID,
Mina SalimiORCID,
Sahar ShafieiORCID,
Hosna KhazaeiORCID,
Mohammad HashemniaORCID
,et al.
PDFFinal Published
29
Jun
2025
Investigation of Peppermint (Mentha piperita) Extract on the Inhibition of Biofilm Formation by Acinetobacter baumannii Strains Isolated from Clinical Samples
Research Article

Investigation of Peppermint (Mentha piperita) Extract on the Inhibition of Biofilm Formation by Acinetobacter baumannii Strains Isolated from Clinical Samples

Zahra Majidi FardORCID,
Negin Irani MaviORCID,
Shokoofeh AkbariORCID,
Yousef ErfaniORCID*,
Sanaz EghtedariORCID
PDFFinal Published
29
Jun
2025
Minocycline Regulates PARP-1 and HDAC3 Pathways to Inhibit Inflammation and Oxidative Stress in LPS-Induced Acute Lung Injury
Research Article

Minocycline Regulates PARP-1 and HDAC3 Pathways to Inhibit Inflammation and Oxidative Stress in LPS-Induced Acute Lung Injury

Chao LuoORCID,
Xixi Zhu,
Jiefei LiangORCID,
Chunyan Zhu,
Guohua Shen,
Weibin WuORCID*
PDFFinal Published
26
May
2025
Cannabidiol Extracted from Cannabis sativa L. Plant Shows Neuroprotective Impacts Against 6-HODA-Induced Neurotoxicity via Nrf2 Signal Transduction Pathway
Research Article

Cannabidiol Extracted from Cannabis sativa L. Plant Shows Neuroprotective Impacts Against 6-HODA-Induced Neurotoxicity via Nrf2 Signal Transduction Pathway

Afsaneh Esfandi,
Ali MehrafarinORCID*,
Sepideh Kalateh JariORCID,
Hassanali Naghdi BadiORCID,
Kambiz LarijaniORCID
PDFFinal Published
25
May
2025
AI-Powered Insights into Drug Resistance in Gastric Cancer: A Path Toward Precision Therapy
Review Article

AI-Powered Insights into Drug Resistance in Gastric Cancer: A Path Toward Precision Therapy

Negar Mottaghi-DastjerdiORCID*,
Mohammad Soltany-Rezaee-RadORCID
PDFFinal Published
20
May
2025
S100B Levels Following Administration of Thiopental and Fentanyl Midazolam Combination in Patients Undergoing Mechanical Ventilation: A Comparative Study
Research Article

S100B Levels Following Administration of Thiopental and Fentanyl Midazolam Combination in Patients Undergoing Mechanical Ventilation: A Comparative Study

Sara SalarianORCID,
Mohammad SistanizadORCID,
Mohammad GharehbeglouORCID,
Keyhan PooraliORCID,
Bahador BagheriORCID*
PDFFinal Published
20
May
2025
Resveratrol Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion by Targeting Lingo-1, NgR1, p75, and RhoA/ROCK-2 Pathways
Research Article

Resveratrol Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion by Targeting Lingo-1, NgR1, p75, and RhoA/ROCK-2 Pathways

Mohabbat Jamhiri,
Fatemeh Safari,
Jalil Alizadeh Ghalenoei,
Fatemeh Zare Mehrjerdi*,
Mansoureh Eslami**
PDFFinal Published
4
May
2025
In Vivo and Bioinformatics Evaluation of Nine Traditional Chinese Medicine Compounds Targeting Acetylcholinesterase and Butyrylcholinesterase Enzymes in Alzheimer’s Disease
Research Article

In Vivo and Bioinformatics Evaluation of Nine Traditional Chinese Medicine Compounds Targeting Acetylcholinesterase and Butyrylcholinesterase Enzymes in Alzheimer’s Disease

Xinyu Yang*
PDFFinal Published
29
Apr
2025
Selective Toxicity of Iron, Manganese Oxide Nanostructure and Laser Wave on Colorectal and Breast Cancer Cell
Research Article

Selective Toxicity of Iron, Manganese Oxide Nanostructure and Laser Wave on Colorectal and Breast Cancer Cell

Aysan Mansournia,
Nasim Nobari*,
Fatemeh GhanbaryORCID,
Behrooz Khezri
PDFFinal Published
19
Apr
2025
Comparison of Pharmacokinetic/Pharmacodynamic Parameters and Clinical Outcomes of Vancomycin Administered in Two Different Dosage Regimens in Patients with Acute Kidney Injury
Research Article

Comparison of Pharmacokinetic/Pharmacodynamic Parameters and Clinical Outcomes of Vancomycin Administered in Two Different Dosage Regimens in Patients with Acute Kidney Injury

Rokhsareh SoufiORCID,
Jamshid SalamzadehORCID,
Ilad Alavi DarazamORCID,
Mahdi AmirdosaraORCID,
Masood Zangi,
Minoosh ShabaniORCID
,et al.
PDFFinal Published
16
Apr
2025
Acetylenic Metabolites and a 2-Phenoxychromone Derivative from the Aerial Parts of Artemisia biennis
Brief Report

Acetylenic Metabolites and a 2-Phenoxychromone Derivative from the Aerial Parts of Artemisia biennis

Maryam Najafi,
Yalda ShokoohiniaORCID,
Mahdi MojarrabORCID*
PDFFinal Published
14
Apr
2025
Evaluation of Antimicrobial Activity of Novel Chimeric M-PEX12 Peptide Against Acinetobacter baumannii
Research Article

Evaluation of Antimicrobial Activity of Novel Chimeric M-PEX12 Peptide Against Acinetobacter baumannii

Yasin Rakhshani,
Hamideh Mahmoodzadeh HosseiniORCID,
Seyed Ali Mirhosseini,
Fatah Sotoodehnejadnematalahi,
Jafar AmaniORCID*
PDFFinal Published
14
Apr
2025
Investigation of the Antioxidant and Cellular Toxicity Activities of Gold Nanoparticles Synthesized Using Cichorium intybus Extract on a Liver Cancer Cell Line
Research Article

Investigation of the Antioxidant and Cellular Toxicity Activities of Gold Nanoparticles Synthesized Using Cichorium intybus Extract on a Liver Cancer Cell Line

Mohammad Mohammad-Alizadeh,
Ahmad Asgharzadeh*,
Maryam Tatari
PDFFinal Published
13
Apr
2025
Study on the Role of Schisandrin B in Ameliorating Hepatic Ischemia-Reperfusion Injury by Modulating Hepatocyte Autophagy
Research Article

Study on the Role of Schisandrin B in Ameliorating Hepatic Ischemia-Reperfusion Injury by Modulating Hepatocyte Autophagy

Zhao Fei,
Pan Haihang,
Chen Xueyang,
Shen Miao*
PDFFinal Published
3
Apr
2025
Pharmacokinetics and Bioequivalence of Two Formulations of Apixaban Tablets: A Double-Blind, Single-Dose, Crossover Study in Healthy Subjects
Research Article

Pharmacokinetics and Bioequivalence of Two Formulations of Apixaban Tablets: A Double-Blind, Single-Dose, Crossover Study in Healthy Subjects

Erfan Abdollahizad,
Azadeh HaeriORCID*,
Abolghasem Jouyban,
Mohammad Reza Afshar Mogaddam,
Zahra Abbasian,
Simin DadashzadehORCID**
PDFFinal Published
26
Mar
2025
Antimicrobial, Anti-inflammatory, Angiogenesis, and Wound Healing Activities of Copper Nanoparticles Green Synthesized by Lupinus arcticus Extract
Research Article

Antimicrobial, Anti-inflammatory, Angiogenesis, and Wound Healing Activities of Copper Nanoparticles Green Synthesized by Lupinus arcticus Extract

Nizar H. Saeedi*,
Abdullah D. Alanazi,
Rawaf Alenazy,
Abdullah F. Shater
PDFFinal Published
15
Mar
2025
Design, Synthesis, and Evaluation of Cytotoxic Effects of Functional Fatty Acid Derivatives as Potential Antineoplastic Agents for Breast Cancer
Research Article

Design, Synthesis, and Evaluation of Cytotoxic Effects of Functional Fatty Acid Derivatives as Potential Antineoplastic Agents for Breast Cancer

Maryam HosseiniORCID,
Farzad KobarfardORCID*,
Salimeh AmidiORCID**,
Shaya Mokhtari,
Anna Sedaghat,
Soraya Shahhosseini
PDFFinal Published
9
Mar
2025
Development of a Potential Bone-Seeking Radiopharmaceutical by Sodium Pyrophosphate Labeled 188Rhenium (188Re-PYP) for Bone Pain Palliation
Research Article

Development of a Potential Bone-Seeking Radiopharmaceutical by Sodium Pyrophosphate Labeled 188Rhenium (188Re-PYP) for Bone Pain Palliation

Mahmoud Moradi,
Mehdi Salehi BaroughORCID*,
Leila Moghaddam-Banaem**,
Fariba Johari Daha,
Sahar Rajabi-Moghadam
PDFFinal Published
9
Mar
2025
Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9
Research Article

Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9

Nigar Houssein-Zadeh,
Leila SadeghiORCID*,
Gholamreza Dehghan
PDFFinal Published
8
Mar
2025
KMT2D Induces M1 Macrophage Polarization to Repress Non-small Cell Lung Cancer Progression via Transcription Activation of ITGAL
Research Article

KMT2D Induces M1 Macrophage Polarization to Repress Non-small Cell Lung Cancer Progression via Transcription Activation of ITGAL

Wen-Tao Wang,
Jie Yang,
Peng-Fei Jiang*
PDFFinal Published
8
Mar
2025
Neuroprotective Effects of Early TLR4 Blockade with Compound C34 in Temporal Lobe Epilepsy: Alleviation of Neuroinflammation and Apoptosis
Research Article

Neuroprotective Effects of Early TLR4 Blockade with Compound C34 in Temporal Lobe Epilepsy: Alleviation of Neuroinflammation and Apoptosis

Roya Varmazyar,
Nima Naderi,
Hanieh Javid,
Rasoul Ghasemi,
Hamid Gholami Pourbadie*
PDFFinal Published
2
Mar
2025
Neurobehavioral and Dopaminergic Dysfunctions Induced by Mixed Metal Exposure in C57BL/6 Mice
Research Article

Neurobehavioral and Dopaminergic Dysfunctions Induced by Mixed Metal Exposure in C57BL/6 Mice

Daeun LeeORCID,
Haesoo KimORCID,
Sarita Pyatha,
Kisok KimORCID*
PDFFinal Published
2
Mar
2025
Design, Synthesis, Anticonvulsant Evaluation, and Molecular Docking Studies of New GABAA Agonist Derivatives
Research Article

Design, Synthesis, Anticonvulsant Evaluation, and Molecular Docking Studies of New GABAA Agonist Derivatives

Mansur Nassiri Koopaei,
Parsa Moghimirad,
Ebrahim Saeedian Moghadam,
Nasrin Nassiri Koopaei,
Massoud Amanlou,
Tahmineh Akbarzadeh
,et al.
PDFFinal Published
24
Feb
2025
Evaluating The Therapeutic Effect of 2-Nitroimidazole on Toxoplasma gondii: An In vitro and In vivo Study Using BALB/c Mice
Research Article

Evaluating The Therapeutic Effect of 2-Nitroimidazole on Toxoplasma gondii: An In vitro and In vivo Study Using BALB/c Mice

Elaheh Ghiasipour,
Javid SadraeiORCID*,
Fatemeh GhaffarifarORCID
PDFFinal Published
24
Feb
2025
Synthesis and Bioactivity Investigation of Novel 2-({2-[(Dialkylamino) Methyl] Quinazolin-4-one-3-yl} Methyl) Benzonitrile Derivatives as Dipeptidyl Peptidase-4 Inhibitory Agent
Research Article

Synthesis and Bioactivity Investigation of Novel 2-({2-[(Dialkylamino) Methyl] Quinazolin-4-one-3-yl} Methyl) Benzonitrile Derivatives as Dipeptidyl Peptidase-4 Inhibitory Agent

Arif ArrahmanORCID,
Noer Luthfianeu Edsyah,
Theresia Thiofani,
Hanifah Sakinatun Khalidah,
Laila Fauziah,
Anjani Widyasintia
,et al.
PDFFinal Published
22
Feb
2025
Design and Characterization of Ricin Based Immunotoxins Against EPHA2 Receptor for Breast Cancer Therapy: An In-Silico Study
Research Article

Design and Characterization of Ricin Based Immunotoxins Against EPHA2 Receptor for Breast Cancer Therapy: An In-Silico Study

Atefeh FarazORCID,
Jafar AmaniORCID*,
Sedigheh ArbabianORCID,
Shohreh Zare Karizi,
Maryam Bikhof TorbatiORCID
PDFFinal Published
22
Feb
2025
Genistein Exerts Anti-proliferative Effects by Regulating Apoptosis and Autophagy-Related Genes and MicroRNAs in Human Urinary Bladder Neoplasm EJ138 Cells: An Experimental and Bioinformatic Study
Research Article

Genistein Exerts Anti-proliferative Effects by Regulating Apoptosis and Autophagy-Related Genes and MicroRNAs in Human Urinary Bladder Neoplasm EJ138 Cells: An Experimental and Bioinformatic Study

Alireza ZiyabakhshORCID,
Mohammad Amin VatankhahORCID,
Farid PakizehORCID,
Ali NosratORCID,
Pouria SobhiORCID,
Mohammad Vakili OjaroodORCID*
,et al.
PDFFinal Published
15
Feb
2025
Assessment of the Efficacy and Safety of Sublingual Melatonin on Symptom Severity, Quality of Life, and Sleep Disorders in Patients with Irritable Bowel Syndrome
Research Article

Assessment of the Efficacy and Safety of Sublingual Melatonin on Symptom Severity, Quality of Life, and Sleep Disorders in Patients with Irritable Bowel Syndrome

Shabnam ShahrokhORCID,
Niloofar Namazi,
Mohammad AbbasinazariORCID*,
Ali Abazarikia,
Amir SadeghiORCID,
Arash MahboubiORCID
PDFFinal Published
12
Feb
2025
Combinatorial Effects of Chrysin with Doxorubicin, 5-Fluorouracil, and Cyclophosphamide on Triple-Negative Breast Cancer Cell Line
Research Article

Combinatorial Effects of Chrysin with Doxorubicin, 5-Fluorouracil, and Cyclophosphamide on Triple-Negative Breast Cancer Cell Line

Sedighe YosefiORCID,
Hamid MadanchiORCID,
Abbas PakdelORCID*,
Parviz KokhaeiORCID,
Maral HematiORCID,
Negar SarmadiORCID
,et al.
PDFFinal Published
11
Feb
2025
Perioperative Use of Pregabalin vs. Duloxetine for Pain Management of Knee Fracture Surgery: A Double-Blind Randomized Clinical Trial
Research Article

Perioperative Use of Pregabalin vs. Duloxetine for Pain Management of Knee Fracture Surgery: A Double-Blind Randomized Clinical Trial

Mohadeseh Masoumi,
Mohammad Soleimani,
Tara ShekariORCID,
Maryam Alaei,
Mehrdad Sheikhvatan,
Mojtaba MojtahedzadehORCID
,et al.
PDFFinal Published
10
Feb
2025
The Protective Effects of Mitochondrial Therapy Against Vincristine- Induced Nephrotoxicity in the Rat’s Renal Proximal Tubular Cells
Research Article

The Protective Effects of Mitochondrial Therapy Against Vincristine- Induced Nephrotoxicity in the Rat’s Renal Proximal Tubular Cells

Armaghan LohrasbiORCID,
Abdollah Arjmand,
Farzaneh Kamranfar,
Mehdi Aghsami*,
Jalal PourahmadORCID**
PDFFinal Published
9
Feb
2025
5-Alpha Reductase Inhibitors on Hypersexuality During the Manic Phase of Bipolar and Psychotic Patients; New Insight to a Well-Known Medicines
Letter

5-Alpha Reductase Inhibitors on Hypersexuality During the Manic Phase of Bipolar and Psychotic Patients; New Insight to a Well-Known Medicines

Mitra Mahmoudi MeymandORCID,
Saeed Mohammad SoleymaniORCID,
Hadi EsmailyORCID*
PDFFinal Published
8
Feb
2025
Therapeutic Mechanisms of Phenothiazine Drugs: A Mini-Review of Advances in Cancer Treatment and Antibiotic Resistance
Review Article

Therapeutic Mechanisms of Phenothiazine Drugs: A Mini-Review of Advances in Cancer Treatment and Antibiotic Resistance

Xuewei ZouORCID*,
Bai XieORCID
PDFFinal Published
4
Feb
2025
Curcumin as a Natural Therapeutic Agent: A Rapid Review of Potential Clinical Uses and Mechanisms of Action
Review Article

Curcumin as a Natural Therapeutic Agent: A Rapid Review of Potential Clinical Uses and Mechanisms of Action

Mohammad Mohajeri,
Reza MomenaiORCID,
Somayyeh Karami-Mohajeri,
Mandana Ohadi*,
Mohammad Amin Raeisi EstabraghORCID**
PDFFinal Published
2
Nov
2024
Effect of Micronized Purified Flavonoid Fraction Containing Hesperidin and Diosmin on Vincristine-Induced Neuropathy in Rats; the Role of Nitric Oxide Pathway
Research Article

Effect of Micronized Purified Flavonoid Fraction Containing Hesperidin and Diosmin on Vincristine-Induced Neuropathy in Rats; the Role of Nitric Oxide Pathway

Nikoo Abharian,
Nima NaderiORCID,
Noushin Nikray,
Mona KhoramjouyORCID,
Shokoofe Noori,
Hamed Shafaroodi
,et al.
PDFFinal Published
29
Jan
2025
Correction

Erratum: Paraquat Exposure Up-regulates Cyclooxygenase-2 in the Lungs, Liver, and Kidneys in Rats [Iran J Pharm Res. 2013; 12(4): e125760]

Editor-in-Chief IJPR*
PDFFinal Published
5
Aug
2025
Expression of Concern for Ethyl Acetate Extract of Licorice Root (Glycyrrhiza glabra) Enhances Proliferation and Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells [Iran J Pharm Res.17(3):e124804]
Expressions of Concern

Expression of Concern for Ethyl Acetate Extract of Licorice Root (Glycyrrhiza glabra) Enhances Proliferation and Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells [Iran J Pharm Res.17(3):e124804]

Editor-in-Chief IJPR*
PDFFinal Published
15
Nov
2025
Expression of Concern for Preventive Effect of Garlic (Allium sativum L.) on Serum Biochemical Factors and Histopathology of Pancreas and Liver in Streptozotocin- Induced Diabetic Rats [IJ Pharm Res. 2013; 12(3): e125679]
Expressions of Concern

Expression of Concern for Preventive Effect of Garlic (Allium sativum L.) on Serum Biochemical Factors and Histopathology of Pancreas and Liver in Streptozotocin- Induced Diabetic Rats [IJ Pharm Res. 2013; 12(3): e125679]

Editor-in-Chief IJPR*
PDFFinal Published
9
Dec
2025
Expression of Concern for Interfering with Lipid Raft Association: A Mechanism to Control Influenza Virus Infection By Sambucus nigra [Iran J Pharm Res. 2017; 16 (3): e124953]
Expressions of Concern

Expression of Concern for Interfering with Lipid Raft Association: A Mechanism to Control Influenza Virus Infection By Sambucus nigra [Iran J Pharm Res. 2017; 16 (3): e124953]

Editor-in-Chief IJPR*
PDFFinal Published