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Iranian Journal of Pharmaceutical Research

e-ISSN 1726-6890
p-ISSN 1735-0328
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Volume 19, Issue 3

49 articles2020-07-31Vol. 19Issue 3XML
31
Jul
2020
Letter to Editor_imported

Nut Consumption and Lung Cancer Risk: Is Linoleic Acid the Secret Weapon?

Raffaella Mormile
PDFFinal Published
31
Jul
2020
Green Nanotechnology-based Gold Nanomaterials for Hepatic Cancer Therapeutics: A Systematic Review
Review Article_imported

Green Nanotechnology-based Gold Nanomaterials for Hepatic Cancer Therapeutics: A Systematic Review

Hamed Barabadi*,
Thomas J. Webster*,
Hossein Vahidi,
Hamed Sabori,
Kaveh Damavandi Kamali,
Fereshteh Jazayeri Shoushtari
,et al.
PDFFinal Published
31
Jul
2020
The Effectiveness of Intranasal Oxytocin on Addiction Severity Index and Anhedonia Symptoms in an Alcoholic Case with Oropharyngeal Cancer, a Protocol for a Single-case Experimental Design Pilot Study
Case Report

The Effectiveness of Intranasal Oxytocin on Addiction Severity Index and Anhedonia Symptoms in an Alcoholic Case with Oropharyngeal Cancer, a Protocol for a Single-case Experimental Design Pilot Study

Bijan Pirnia,
Mostafa Hamdieh*,
Maryam Kazemi Ashtiani,
Parastoo Malekanmehr,
Kambiz Pirnia,
Alireza Zahiroddin
,et al.
PDFFinal Published
31
Jul
2020
A Randomized, Open, Single-Centre, Crossed Study of the Effect of Food on the Pharmacokinetics of One Oral Dose of Alflutinib Mesylate Tablets (AST2818) in Healthy Male Subjects
Original Article

A Randomized, Open, Single-Centre, Crossed Study of the Effect of Food on the Pharmacokinetics of One Oral Dose of Alflutinib Mesylate Tablets (AST2818) in Healthy Male Subjects

Songlin Zhu,
Jun Deng,
Qi Tang,
Jianfu Heng,
Jingjing Qu,
Yong Chen
,et al.
PDFFinal Published
31
Jul
2020
In-vivo Anti-inflammatory Activity of Hydrocotyle umbellata L. aerial parts and Isolation of the Main Phytochemicals
Original Article

In-vivo Anti-inflammatory Activity of Hydrocotyle umbellata L. aerial parts and Isolation of the Main Phytochemicals

Sherif A. Hamdy*,
Esther T. Menze,
Hala M. El Hefnawy,
Shadia M. Azzam,
Elsayed A. Aboutabl
PDFFinal Published
31
Jul
2020
Preparation, Statistical Optimization and In-vitro Characterization of a Dry Powder Inhaler (DPI) Containing Solid Lipid Nanoparticles Encapsulating Amphotericin B: Ion Paired Complexes with Distearoyl Phosphatidylglycerol
Original Article

Preparation, Statistical Optimization and In-vitro Characterization of a Dry Powder Inhaler (DPI) Containing Solid Lipid Nanoparticles Encapsulating Amphotericin B: Ion Paired Complexes with Distearoyl Phosphatidylglycerol

Ehsan Mehrabani Yeganeh,
Hossein Bagheri,
Reza Mahjub*
PDFFinal Published
31
Jul
2020
Fabrication and In-vitro Evaluation of Buccal Mucoadhesive Tablet of Meloxicam
Original Article

Fabrication and In-vitro Evaluation of Buccal Mucoadhesive Tablet of Meloxicam

Mahshid Arabi,
Seyed Alireza Mortazavi*,
Zahra Jafariazar,
Hassan Farhadnejad,
Golnoosh Alipour Harisa,
Yousef Fatahi
PDFFinal Published
31
Jul
2020
The Contribution of VKORC1 and CYP2C9 Genetic Polymorphisms and Patients’ Demographic Characteristics with Warfarin Maintenance Doses: A Suggested Warfarin Dosing Algorithm
Original Article

The Contribution of VKORC1 and CYP2C9 Genetic Polymorphisms and Patients’ Demographic Characteristics with Warfarin Maintenance Doses: A Suggested Warfarin Dosing Algorithm

Esmat Khaleqsefat,
Mohammad Khalaj-Kondori*,
Mortaza Jabarpour Bonyadi,
Hamid Soraya,
Behnam Askari
PDFFinal Published
31
Jul
2020
The Effect of Treating Vitamin D Deficiency or Insufficiency on Serum Adiponectin, Leptin and Insulin Resistance of Type 2 Diabetes Mellitus Patients: A Pilot Study
Original Article

The Effect of Treating Vitamin D Deficiency or Insufficiency on Serum Adiponectin, Leptin and Insulin Resistance of Type 2 Diabetes Mellitus Patients: A Pilot Study

Afshin Gharekhani,
Farzad Najafipour,
Hananeh Baradaran,
Parisa Tagharrobi,
Haleh Rezaee*
PDFFinal Published
31
Jul
2020
Donepezil and Rivastigmine: Pharmacokinetic Profile and Brain-targeting After Intramuscular Administration in Rats
Original Article

Donepezil and Rivastigmine: Pharmacokinetic Profile and Brain-targeting After Intramuscular Administration in Rats

Jana Zdarova Karasova*,
Martina Hrabinova,
Marketa Krejciova,
Daniel Jun,
Kamil Kuca
PDFFinal Published
31
Jul
2020
Spectrophotometric Methods for Determination of Sunitinib in Pharmaceutical Dosage Forms Based on Ion-pair Complex Formation
Original Article

Spectrophotometric Methods for Determination of Sunitinib in Pharmaceutical Dosage Forms Based on Ion-pair Complex Formation

Effat Souri*,
Eynollah Amoon,
Nazanin Shabani Ravari,
Fereshteh Keyghobadi,
Maliheh Barazandeh Tehrani
PDFFinal Published
31
Jul
2020
Neuro-Behavioral Profile and Toxicity of the Essential Oil of Dorema ammoniacum Gum as an Anti-seizure, Anti-nociceptive, and Hypnotic Agent with Memory-enhancing Properties in D-Galactose Induced Aging Mice
Original Article

Neuro-Behavioral Profile and Toxicity of the Essential Oil of Dorema ammoniacum Gum as an Anti-seizure, Anti-nociceptive, and Hypnotic Agent with Memory-enhancing Properties in D-Galactose Induced Aging Mice

Reza Jahani,
Mona Khoramjouy,
Azadeh Nasiri,
Maryam Sojoodi Moghaddam,
Yousef Asgharzadeh Salteh,
Mehrdad Faizi*
PDFFinal Published
31
Jul
2020
Naringenin Enhances the Anti-Cancer Effect of Cyclophosphamide against MDA-MB-231 Breast Cancer Cells Via Targeting the STAT3 Signaling Pathway
Original Article

Naringenin Enhances the Anti-Cancer Effect of Cyclophosphamide against MDA-MB-231 Breast Cancer Cells Via Targeting the STAT3 Signaling Pathway

Shokoofe Noori,
Mostafa Rezaei Tavirani,
Niloofar Deravi,
Mohammad Ismaiil Mahboobi Rabbani,
Afshin Zarghi*
PDFFinal Published
31
Jul
2020
Synthesis, Molecular Docking and Cytotoxic Activity Evaluation of Organometallic Thiolated Gold(I) Complexes
Original Article

Synthesis, Molecular Docking and Cytotoxic Activity Evaluation of Organometallic Thiolated Gold(I) Complexes

Zeinab Faghih,
Alireza Yazdani Kachoei,
Hossein Alizadeh,
Suphia Emamdoost,
Shima Shirkhan,
Masood Fereidoonnezhad*
PDFFinal Published
31
Jul
2020
Inhibition of Cyclin-dependent Kinase (CDK) Decreased Survival of NB4 Leukemic Cells: Proposing a p53-Independent Sensitivity of Leukemic Cells to Multi-CDKs Inhibitor AT7519
Original Article

Inhibition of Cyclin-dependent Kinase (CDK) Decreased Survival of NB4 Leukemic Cells: Proposing a p53-Independent Sensitivity of Leukemic Cells to Multi-CDKs Inhibitor AT7519

Atieh Pourbagheri-Sigaroodi,
Ava Safaroghli-Azar,
Mehrnoosh Shanaki,
Amir-Mohammad Yousefi,
Ali Anjam Najmedini,
Davood Bashash*
PDFFinal Published
31
Jul
2020
Synthesis and Bioactivity of a Cyclopolypeptide from Caribbean Marine Sponge
Original Article

Synthesis and Bioactivity of a Cyclopolypeptide from Caribbean Marine Sponge

Rajiv Dahiya*,
Stacy Rampersad,
Terry G. Ramnanansingh,
Komalpreet Kaur,
Ramninder Kaur,
Rita Mourya
,et al.
PDFFinal Published
31
Jul
2020
Metal (II) Complexes of Fluconazole: Thermal, XRD and Cytotoxicity Studies
Original Article

Metal (II) Complexes of Fluconazole: Thermal, XRD and Cytotoxicity Studies

Syed Imran Ali*,
Zi-Ning Lei,
Mohsin Ali,
Konatsu Kojima,
Mansoor Ahmed,
Richard Peng
,et al.
PDFFinal Published
31
Jul
2020
Development of a GC-MS Method for Determination of Various Polycyclic Aromatic Hydrocarbons in Iranian Traditional and Semi-industrial Taftoon Bread
Original Article

Development of a GC-MS Method for Determination of Various Polycyclic Aromatic Hydrocarbons in Iranian Traditional and Semi-industrial Taftoon Bread

Vahideh Moradi,
Seyed Mahdi Seyedain Ardabili,
Attaollah Shakoori*,
Seyed Ebrahim Hoseyni
PDFFinal Published
31
Jul
2020
Synthetic Biology Based on Genetic Logic Circuit, Using the Expression of Drug Resistance, BCRP Pump in MCF-7 Cancer Cell Line
Original Article

Synthetic Biology Based on Genetic Logic Circuit, Using the Expression of Drug Resistance, BCRP Pump in MCF-7 Cancer Cell Line

Marzieh Gerami,
Modjtaba Emadi-Baygi*,
Mohammad Eshghi,
Fatemeh Elahian,
Razieh Heidari,
Mehdi Hosseinzadeh
PDFFinal Published
31
Jul
2020
Expression, Purification and Docking Studies on IMe-AGAP, the First Antitumor-analgesic Like Peptide from Iranian Scorpion Mesobuthus eupeus
Original Article

Expression, Purification and Docking Studies on IMe-AGAP, the First Antitumor-analgesic Like Peptide from Iranian Scorpion Mesobuthus eupeus

Zeinab Dehghan,
Hoda Ayat*,
Ali Mohammad Ahadi
PDFFinal Published
31
Jul
2020
Antitumor Activity and Mechanism Study of Riluzole and Its Derivatives
Original Article

Antitumor Activity and Mechanism Study of Riluzole and Its Derivatives

Xiang-Long Wu*,
Liu Liu,
Qing-Chuan Wang,
Hai-Fang Wang,
Xiang-Rong Zhao,
Xu-Bin Lin
,et al.
PDFFinal Published
31
Jul
2020
Ficus Carica L. Latex: Possible Chemo-Preventive, Apoptotic Activity and Safety Assessment
Original Article

Ficus Carica L. Latex: Possible Chemo-Preventive, Apoptotic Activity and Safety Assessment

Fereshteh Jeivad,
Nargues Yassa,
Seyed Nasser Ostad,
Zahra Hassannejad,
Gholamreza Hassanzadeh Gheshlaghi,
Omid Sabzevari*
PDFFinal Published
31
Jul
2020
Effects of Fish Oil Supplementation on Pregnancy Outcomes in Pregnant Women Referred to Kosar Hospital
Original Article

Effects of Fish Oil Supplementation on Pregnancy Outcomes in Pregnant Women Referred to Kosar Hospital

Nazanin Gholami,
Shokoh Abotorabi*,
Fatemeh Lalooha,
Sonia Oveisi
PDFFinal Published
31
Jul
2020
Trimetazidine Increases Plasma MicroRNA-24 and MicroRNA-126 Levels and Improves Dyslipidemia, Inflammation and Hypotension in Diabetic Rats
Original Article

Trimetazidine Increases Plasma MicroRNA-24 and MicroRNA-126 Levels and Improves Dyslipidemia, Inflammation and Hypotension in Diabetic Rats

Fatemeh Ramezani-Aliakbari,
Mohammad Badavi*,
Mahin Dianat,
Seyyed Ali Mard,
Akram Ahangarpour
PDFFinal Published
31
Jul
2020
Approaches for the Treatment of SARS-CoV-2 Infection: A Pharmacologic View and Literature Review
Review Article_imported

Approaches for the Treatment of SARS-CoV-2 Infection: A Pharmacologic View and Literature Review

Hajar Mohammadi Barzelighi,
Bahram Daraei*,
Farzaneh Dastan
PDFFinal Published
31
Jul
2020
Frequency of Antimicrobial Resistance and Class 1 and 2 Integrons in Escherichia Coli Strains Isolated from Urinary Tract Infections
Original Article

Frequency of Antimicrobial Resistance and Class 1 and 2 Integrons in Escherichia Coli Strains Isolated from Urinary Tract Infections

Mahboobe Mirnezami,
Reza Ranjbar,
Mohammad Niakan*,
Mohammad Hossein Ahmadi
PDFFinal Published
31
Jul
2020
Isolation of Polyclonal Single-Chain Fragment Variable (scFv) Antibodies Against Venomous Snakes of Iran and Evaluation of Their Capability in Neutralizing the Venom
Original Article

Isolation of Polyclonal Single-Chain Fragment Variable (scFv) Antibodies Against Venomous Snakes of Iran and Evaluation of Their Capability in Neutralizing the Venom

Maryam Kadkhodazadeh,
Masoumeh Rajabibazl*,
Mohammad Motedayen,
Solmaz Shahidi,
Ziba Veisi Malekshahi,
Azam Rahimpour
,et al.
PDFFinal Published
31
Jul
2020
Optimization of Buffer Additives for Efficient Recovery of hGM-CSF from Inclusion Bodies Using Response Surface Methodology
Original Article

Optimization of Buffer Additives for Efficient Recovery of hGM-CSF from Inclusion Bodies Using Response Surface Methodology

Mina Ahmadian,
Ali Jahanian-Najafabadi,
Vajihe Akbari*
PDFFinal Published
31
Jul
2020
Protective Effects of a Nano-Formulation of Curcumin against Cuprizone-Induced Demyelination in the Mouse Corpus Callosum
Original Article

Protective Effects of a Nano-Formulation of Curcumin against Cuprizone-Induced Demyelination in the Mouse Corpus Callosum

Mahsa Motavaf,
Majid Sadeghizadeh*,
Sadegh Babashah,
Leila Zare,
Mohammad Javan*
PDFFinal Published
31
Jul
2020
Multi-drug resistance of Staphylococcus aureus Strains in Baqiyatallah hospital: a Primary Step Towards Digital Health Biomonitoring Systems
Original Article

Multi-drug resistance of Staphylococcus aureus Strains in Baqiyatallah hospital: a Primary Step Towards Digital Health Biomonitoring Systems

Ahmadreza Katoziyan,
Abbas Ali Imani Fooladi*,
Ramezan Ali Taheri,
Saba Vatanpour
PDFFinal Published
31
Jul
2020
Structure Prediction and Expression of Modified rCTLA4-Ig as a Blocker for B7 Molecules
Original Article

Structure Prediction and Expression of Modified rCTLA4-Ig as a Blocker for B7 Molecules

Hossein Mahdizadeh,
Jafar Salimian*,
Zahra Noormohammadi,
Jafar Amani,
Raheleh Halabian,
Yunes Panahi
PDFFinal Published
31
Jul
2020
Hypericin Induces Apoptosis in AGS Cell Line with No Significant Effect on Normal Cells
Original Article

Hypericin Induces Apoptosis in AGS Cell Line with No Significant Effect on Normal Cells

Misagh Naderi,
Mahtab Rahmani Cherati,
Ali Mohammadian,
Mohammad Baghery Bidhendy,
Saeedeh Ghiasvand,
Hadi Zare Marzouni
,et al.
PDFFinal Published
31
Jul
2020
Potential Anti-Tumor Activity of Kefir-Induced Juglone and Resveratrol Fractions Against Ehrlich Ascites Carcinoma-Bearing BALB/C Mice
Original Article

Potential Anti-Tumor Activity of Kefir-Induced Juglone and Resveratrol Fractions Against Ehrlich Ascites Carcinoma-Bearing BALB/C Mice

Erhan Bozkurt,
Emre Atay*,
Gökhan Pektaş,
Ayşe Ertekin,
Ayhan Vurmaz,
Ömer Adil Korkmaz
,et al.
PDFFinal Published
31
Jul
2020
Synthesis of Novel Peptides Using Unusual Amino Acids
Original Article

Synthesis of Novel Peptides Using Unusual Amino Acids

Bahareh Talaei,
Vaezeh Fathi Vavsari,
Saeed Balalaie*,
Armin Arabanian,
Hamid Reza Bijanzadeh
PDFFinal Published
31
Jul
2020
Evaluation of Swab and Rinse Sampling Procedures and Recovery Rate Determination in Cleaning Validation Considering Various Surfaces, Amount and Nature of the Residues and Contaminants
Original Article

Evaluation of Swab and Rinse Sampling Procedures and Recovery Rate Determination in Cleaning Validation Considering Various Surfaces, Amount and Nature of the Residues and Contaminants

Somayeh Lamei Ramandi,
Ramin Asgharian*
PDFFinal Published
31
Jul
2020
Flavonoid Calycopterin Induces Apoptosis in Human Prostate Cancer Cells In-vitro
Original Article

Flavonoid Calycopterin Induces Apoptosis in Human Prostate Cancer Cells In-vitro

Reza Lotfizadeh,
Houri Sepehri*,
Farnoosh Attari*,
Ladan Delphi
PDFFinal Published
31
Jul
2020
Significant Anticancer Activity of a Venom Fraction Derived from the Persian Gulf Sea Anemone, Stichodactyla haddoni
Original Article

Significant Anticancer Activity of a Venom Fraction Derived from the Persian Gulf Sea Anemone, Stichodactyla haddoni

Ziba Moghadasi,
Delavar Shahbazzadeh*,
Shahla Jamili,
Nariman Mosaffa,
Kamran Pooshang Bagheri*
PDFFinal Published
31
Jul
2020
Bio-removal of Heavy Metalsusing Iron-oxidizing Bacteria: A Novel Approach in Environmental Biotechnology
Original Article

Bio-removal of Heavy Metalsusing Iron-oxidizing Bacteria: A Novel Approach in Environmental Biotechnology

Sareh Farahani,
Abbas Akhavan Sepahi*,
Seyed Abbas Shojaosadati,
Farzaneh Hosseini
PDFFinal Published
31
Jul
2020
The Effect of Erythropoietin Administration on the Serum Level of YKL-40, pro-BNP and IL-6 in Coronary Surgery Patients
Original Article

The Effect of Erythropoietin Administration on the Serum Level of YKL-40, pro-BNP and IL-6 in Coronary Surgery Patients

Mahnoosh Foroughi,
Zohre Mohammadi,
Masoud Majidi Tehrani,
Mahmood Bakhtiari,
Ali Dabbagh*,
Mostafa Haji Molahoseini
PDFFinal Published
31
Jul
2020
Protective Effects of Crocin Against Hepatic Damages in D-galactose Aging Model in Rats
Original Article

Protective Effects of Crocin Against Hepatic Damages in D-galactose Aging Model in Rats

Seyedeh Farzaneh Omidkhoda,
Soghra Mehri,
Somaye Heidari,
Hossein Hosseinzadeh*
PDFFinal Published
31
Jul
2020
Comparison of Mirtazapine and Olanzapine on Nausea and Vomiting following Anthracycline-cyclophosphamide Chemotherapy Regimen in Patients with Breast Cancer
Original Article

Comparison of Mirtazapine and Olanzapine on Nausea and Vomiting following Anthracycline-cyclophosphamide Chemotherapy Regimen in Patients with Breast Cancer

Alimohammad Maleki,
Mojtaba Ghadiyani,
Jamshid Salamzadeh,
Sina Salari,
Seyedshahab Banihashem,
Maria Tavakoli-Ardakani
PDFFinal Published
31
Jul
2020
Development and Characterization of Niosomal Gel System using Lallementia royaleana Benth. mucilage for the treatment of Rheumatoid Arthritis
Original Article

Development and Characterization of Niosomal Gel System using Lallementia royaleana Benth. mucilage for the treatment of Rheumatoid Arthritis

Snigdha Bhardwaj*,
Sonam Bhatia
PDFFinal Published
31
Jul
2020
A Novel 1,3-Β-Glucanase Gene from the Metagenomic Expression Library of Achatina Fulica’s Digestive Gland
Original Article

A Novel 1,3-Β-Glucanase Gene from the Metagenomic Expression Library of Achatina Fulica’s Digestive Gland

Maris Kurniawati,
Purkan,
Sri Sumarsih,
Afaf Baktir*
PDFFinal Published
31
Jul
2020
Pharmacological Evidences for Curcumin Neuroprotective Effects against Lead-Induced Neurodegeneration: Possible Role of Akt/GSK3 Signaling Pathway
Original Article

Pharmacological Evidences for Curcumin Neuroprotective Effects against Lead-Induced Neurodegeneration: Possible Role of Akt/GSK3 Signaling Pathway

Negin Goudarzi,
Sanaz Mohammad Valipour,
Akram Nooritahneh,
Majid Motaghinejad*,
Manijeh Motevalian,
Sepideh Safari
,et al.
PDFFinal Published
31
Jul
2020
Epidrug Modulated Expression of MiR­-152 and MiR-148a Reverse Cisplatin Resistance in Ovarian Cancer Cells: An Experimental In-vitro Study
Original Article

Epidrug Modulated Expression of MiR­-152 and MiR-148a Reverse Cisplatin Resistance in Ovarian Cancer Cells: An Experimental In-vitro Study

Sahel Khajehnoori,
Fatemeh Zarei,
Mahta Mazaheri*,
Ali Dehghani-Firoozabadi
PDFFinal Published
31
Jul
2020
Dextran-based Nanomicelle System with Directly Ester-bound Gadolinium Chelates as a Magnetic Resonance Imaging Contrast Agent for Tumor Detection
Original Article

Dextran-based Nanomicelle System with Directly Ester-bound Gadolinium Chelates as a Magnetic Resonance Imaging Contrast Agent for Tumor Detection

Lirong Ma,
Weiyu Yang,
Dingmei Wu,
Mengmeng Jiang,
Xiuzhong Yao*,
Weiyu Weng*
PDFFinal Published
31
Jul
2020
New Potentiometric Screen-printed Sensors for Determination of Trimebutine Drug in Tablets, Serum and Urine Samples
Original Article

New Potentiometric Screen-printed Sensors for Determination of Trimebutine Drug in Tablets, Serum and Urine Samples

Tamer Awad Ali*,
Gehad Genidy Mohamed,
Adel Zaki El-Sonbati,
Mostafa Amin Diab,
Ahmed Mohmed Elkfass
PDFFinal Published
31
Jul
2020
Early Conversion to Tacrolimus Vs Cyclosporine Continuation in Normally Functioning Kidney Allograft: A Single-Center Study
Research Article

Early Conversion to Tacrolimus Vs Cyclosporine Continuation in Normally Functioning Kidney Allograft: A Single-Center Study

Laya Azizzadeh,
Seyed Amirhossein Fazeli,
Farshad Hashemian,
Sanaz Dehghani,
Seyedeh Samaneh Ahmadi,
Gholamreza Pourmand*
PDFFinal Published
31
Jul
2020
Measurement of Hansen Solubility Parameters of Human Stratum Corneum
Research Article

Measurement of Hansen Solubility Parameters of Human Stratum Corneum

Negin Ezati,
Michael Stephen Roberts,
Qian Zhang,
Hamid Reza Moghimi*
PDFFinal Published