Liver Hemoperfusion and Liver Dialysis Methods in Liver Diseases

About this book

The liver metabolises nutrients, detoxifies the blood, produces essential proteins and clotting factors, stores energy, and regulates blood glucose. When it fails, the consequences cascade: jaundice, chronic fatigue, abnormal bleeding, hepatic encephalopathy, ascites, and in advanced cases multi-organ failure.

Liver failure may be acute — often from viral infection, drug toxicity, or metabolic disturbance — or chronic, developing gradually from viral hepatitis, non-alcoholic fatty liver disease, cirrhosis, prolonged medication or toxin exposure, and genetic or autoimmune causes.

Transplantation is highly effective but constrained: cost, complexity, donor shortage, rejection risk, lifelong immunosuppression, and the need for continuing medical supervision. That gap has driven sustained work on alternatives — hepatoprotective drugs, cell therapy, tissue engineering, and the detoxification techniques that are this book's focus.

The book examines those extracorporeal support methods alongside the preventive measures that slow progression: lifestyle modification, diet, avoiding alcohol, and controlling diabetes and hypertension.

What the book covers