Primary Sclerosing Cholangitis: An Inflammatory Liver Disease

About this book

The liver sustains metabolism, detoxification, immune regulation, and energy storage — and many of its diseases are overlooked, by the public and sometimes within specialist medicine too. Primary sclerosing cholangitis is one of the least known and most consequential: a chronic inflammation of the bile ducts that can progressively impair liver function.

PSC is rare but progressive, and it typically advances silently, which makes diagnosis, treatment, and long-term management genuinely difficult. It occurs more often in people with inflammatory bowel disease, ulcerative colitis in particular, and its cause remains unknown. In the absence of a definitive cure, awareness, early diagnosis, and consistent care are the pillars that control progression and protect quality of life.

Written from years of clinical and research experience, the book sets out to make complex material clear and usable — for patients and families, and equally for general practitioners, medical students, and health system administrators. It deliberately addresses the human and emotional dimensions of the illness alongside the science.

Every illness is more than just a collection of signs and symptoms — it is a human experience intertwined with fear, hope, despair, perseverance, and resilience.Prof. Seyed-Moayed Alavian — from the introduction

What the book covers