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- Comprehensive Guide to Fatty Liver, Gallbladder, and Pancreatic Diseases
- Bread of Tomorrow: Smart Nutrition with Supplements and Modern Technologies
- Fitness: Healthy Nutrition and Effective Exercise
- Smart Fibers: Glucomannan, Inulin, and the Future of Functional Nutrition
- Massage Therapy: Healing Touch for Body and Soul
- Medical Checkup: Prevention and Treatment of Obesity and Fatty Liver
- Comprehensive Guide for Patients and the Community: Hepatitis C
- Ursodeoxycholic Acid: The Story of a Life-Saving Bile Acid
- Olive: The Green Gold of Health
- Alcohol: The Silent Enemy
- Saffron: The Red Gold of Health
- Tirzepatide: A New Perspective on Obesity, Metabolism, and the Future of Treatment
- Coffee and Health: The Truth Behind the Beloved Cup
- Obesity and Stomach Botox: What You Need to Know
- Dates: Natural Fuel for a Healthy Body, a Healthy Society
- Liver Hemoperfusion and Liver Dialysis Methods in Liver Diseases
- Healthy Food: The Secret of Japanese Health
- Semaglutide: A New Look at Obesity, Diabetes, Fatty Liver and the Future of Treatment
- Healthy Plate, Healthy Life
- The Four Liver Heroes: SAMe, Phosphatidylcholine–Silybin, S-Acetyl Glutathione, and Vitamin E
- Seaweeds and Their Role in Health
- Probiotics and Liver & Digestive Health
- Silymarin: The Secret to Liver Health (English Edition)
- Indexing Sources for STM Journals
- Fatty Liver – The Silent Enemy
- Acid Reflux: When Stomach Acid Rises Up
- Medical Treatment of Obesity
- New Publishing Technologies: For STM Journals
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- Protecting Yourself: Understanding and Preventing Hepatitis A and E
- Peptides: Keys to Health from a Future Perspective
- High Blood Lipids: The Silent Threat to Your Heart
- What to Eat, What Not to Eat: A Look at Fatty Liver (English Edition)
- Erectile Dysfunction: Causes, Factors, and Treatments
- From A to Z on Hepatitis C in Thalassemia
- Fatty Liver: Patient Guidance in Arabic
- The Healthy Table and Iranian Cuisine
- Wilson’s Disease: The Liver and Brain Under Siege by Copper
- Medical Check-Up: Prevention and Treatment of Obesity and Fatty Liver (English Edition)
- Dynamics of the Mammalian Sperm Head
- Comprehensive Guide to Hepatitis B for the Public
- Comprehensive Guideline for Hepatitis B People Awareness (Persian)
- Comprehensive Guideline for Hepatitis C People Awareness
- Liver Cirrhosis: Patient Awareness
- Guía integral sobre la Hepatitis C para información pública
- Hepatitis C: Patient Awareness (Persian)
- Liver Fibrosis: From Fibrosis to Cirrhosis
- Beyond Rankings: Publishing for Impact, Not Index
- Fatty Liver: Patient Education
- Alpha-Lipoic Acid: The Universal Antioxidant
- Slimming Injections and Liver Health
- Autoimmune Hepatitis and Biliary Cholangitis: A Comprehensive Guide for Patients
- What to Eat, What Not to Eat: A Look at Fatty Liver
- Obesity and Weight Loss: Causes, Prevention, and Treatment
- Hepatitis B: A Comprehensive Guide for Patients
- Autoimmune Hepatitis and Biliary Cholangitis (Persian Edition)
- Healthy Liver with Exercise
- Rights and Support for Patients with Transmissible Infectious Diseases, Focusing on Hepatitis B and C
- Silymarin: The Secret to Liver Health
- The Power of Nuts and Seeds
- Practical Guide to the Use of Nutritional, Dietary, and Sports Supplements
- Liver Elastography and FibroScan
- Rights and Support for Patients with Transmissible Infectious Diseases: Focus on Hepatitis B & C (English Edition)
- Primary Sclerosing Cholangitis: An Inflammatory Liver Disease
- All About Liv.52 DS
- Exercise and Liver Health: A Practical Guide for Patients and Gyms
- Food as Medicine: The Impact of Nutrition on Disease Prevention and Recovery
- Primary Biliary Cholangitis: The Silent Liver Disease
- Fatty Liver, Gallbladder and Pancreatic Diseases: A Comprehensive Guide for Patients and the Community (English Edition)
- Human Papillomavirus (HPV): A Silent Virus, A Serious Threat (Arabic Edition)
- Autoimmune Hepatitis: When the Body Attacks Itself
- Comprehensive Guideline for Hepatitis B People Awareness (English Edition)
Silymarin: The Secret to Liver Health (English Edition)
The English edition of the Brieflands guide to silymarin, the milk thistle extract used alongside conventional care in liver disease. Prof. Seyed-Moayed Alavian and Dr. Seyede Hoda Alavian set out the scientific basis, the clinical evidence, and the limits of what a supplement can do.
English edition — properties, applications, and clinical research
Silymarin: The Secret to Liver Health
Silymarin, the extract of milk thistle seed, has been credited with protecting the liver for a very long time. This book asks what the evidence actually supports — where silymarin belongs alongside conventional treatment, and where it does not replace it.

Authors
Prof. Seyed-Moayed Alavian, Dr. Seyede Hoda Alavian
Publisher
Language
English
ISBN-13
978-90-8351-736-0
Cataloguing
Registered in the Netherlands
Subject
Hepatoprotection, complementary therapy, milk thistle (Silybum marianum)
Other edition
Audience
Healthcare professionals, researchers, and patients
Interested in this book?
The English edition is published by Brieflands. For copies, institutional orders, or translation rights, contact the publisher directly. A Persian edition is also available.
About this book
Liver disease is among the largest global health burdens, affecting millions of people each year — from viral hepatitis and fatty liver disease through to cirrhosis and liver cancer, often with severe complications and, in many cases, death. Poor diet, sedentary living, alcohol, and rising rates of obesity have all made that burden heavier.
Medical research and therapy have advanced considerably, but the complexity of liver disorders means complementary approaches are still sought alongside conventional treatment. It is in that space that natural remedies and supplements such as silymarin have attracted sustained attention.
Silymarin, extracted from the seeds of milk thistle (Silybum marianum), has long been valued for its hepatoprotective properties, and a growing body of research examines its antioxidant, anti-inflammatory and regenerative activity — its capacity to protect liver cells from damage, support their repair, and improve liver function.
This book explores those roles in full: the scientific foundations, the clinical applications, and silymarin's potential as a supplement in managing liver conditions. It also situates that discussion in the broader context of complementary therapy, arguing that evidence-based supplements should be integrated with standard medical treatment rather than substituted for it.
My hope is that this guide will serve as a valuable resource for healthcare professionals, researchers, and patients alike, fostering greater awareness and understanding of the pivotal role Silymarin and similar supplements can play in combating liver diseases worldwide.Prof. Seyed-Moayed Alavian, Gastroenterology and Hepatology Specialist — from the preface
What the book covers
The global liver burden
Viral hepatitis, fatty liver, cirrhosis and liver cancer, and the lifestyle factors driving them.
What silymarin is
The milk thistle extract, its active constituents, and how it is prepared.
Mechanisms
Antioxidant, anti-inflammatory, and regenerative activity at the level of the liver cell.
Clinical research
What trials and reviews report about efficacy, and where the evidence remains limited.
Practical use
Dosage considerations, tolerability, and interactions to be aware of.
Complementary care
How evidence-based supplements sit alongside — not instead of — standard treatment.
Important. Silymarin is a supplement, not a treatment for liver disease. It is not a substitute for antiviral therapy in hepatitis B or C, for the management of cirrhosis, or for any prescribed medication, and evidence of clinical benefit remains mixed for several indications. Silymarin can interact with medicines metabolised by the liver. Anyone with liver disease should discuss supplement use with their hepatologist before starting.