IJ Pharmaceutical Research
6
Jan
2025
Research Article
Melatonin Aids in Treating Mood and Sleep Problems Resulting from Hormonal Therapy in Breast Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial
Nima Vaziri,
Melika Shakourifar,
Parinaz Sattari,
Aliereza Sadeghi
,
,Mehran Sharifi,
Ayda Moghadas
,et al.5
Jan
2025
Research Article
The Impact of Coenzyme Q10 on Cognitive Dysfunction, Antioxidant Defense, Cholinergic Activity, and Hippocampal Neuronal Damage in Monosodium Glutamate-Induced Obesity
Zahra Erfanmanesh,
Mohammad Amin Edalatmanesh*,
*,Mokhtar Mokhtari
4
Jan
2025
Research Article
Bupropion Showed Neuroprotective Impacts Against Cerebral Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Inflammation
Saeid Baba Ahmadi,
Zeinab Afrand Khalilabad,
Seyedeh Sepideh Alemohammad,
Hasan Yousefi Manesh,
Alireza Abdollahi,
,Farahnaz Jazayeri
,et al.25
Dec
2024
Research Article
Evaluating the Inhibitory Effects of Probiotic Bacteria and Propolis Extracts on the Growth and Histopathological Changes in Gastric Tissues of Helicobacter pylori Challenged Wistar Rats
Roghayeh Kiani,
Naheed Mojgani*,
*,Farzad Kobarfard,
,Parvaneh Saffarian,
Seyed Abdulmajid Ayatollahi,
Mona Khoramjouy
23
Dec
2024
Research Article
Selective Toxicity Mechanisms of Carbon Nanotubes and Near-Infrared Light Wave on the Colon and Hepatoma Cancer Cells
Farshad Lotfollahzadeh,
Nasim Nobari,
Fatemeh Ghanbary*,
*,Hossein Hooshyar
17
Dec
2024
Research Article
Cost-Utility Analysis of Trastuzumab-Emtansine Versus Trastuzumab for the Treatment of Residual Invasive HER-2-Positive Breast Cancer in Iran
Homa Hemati,
,Marzieh Nosrati,
,Meysam Seyedifar*
*16
Dec
2024
Research Article
The Effect of Intrauterine Administration of Growth Hormone on IVF Success Rate in Recurrent Implantation Failure Women: A Randomized Clinical Trial
Fatemeh Amirkhanloo,
Mohammad Javanbakht,
Sarah Lotfi,
,Ghazal Sahraiyan,
Razieh Akbari,
Elham Feizabad
,et al.16
Dec
2024
Research Article
Evaluation of Oral Nano-Silymarin Formulation Efficacy in the Prevention of Hand-Foot Syndrome and Neuropathy Induced by XELOX or m-FOLFOX6 Regimens in Metastatic Colorectal Cancer: A Triple-Blinded, Randomized Clinical Trial
Hedyieh Karbasforooshan,
Hossein Rahimi,
Omid Arasteh,
,Abolghasem Allahyari,
,Mehdi Varmaghani,
Mahdi Jannati
,et al.13
Dec
2024
Research Article
Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes (SOD1, GPx, HO-1) by Quercetin Loaded in Solid Lipid Nanoparticles and Curcumin in Atherosclerosis Therapy
Masoumeh Shamsi,
Ghorban Mohammadzadeh,
,Mahdi Hatami,
Mohammadreza Roshanazadeh,
Mojgan Noor-Behbahani,
Mojtaba Rashidi*
*8
Dec
2024
Research Article
Predictive Insights Into Bioactive Compounds from Streptomyces as Inhibitors of SARS-CoV-2 Mutant Strains by Receptor Binding Domain: Molecular Docking and Dynamics Simulation Approaches
Hourieh Kalhor,
Mohammad Hossein Mokhtarian,
,Hamzeh Rahimi,
Behzad Shahbazi,
Reyhaneh Kalhor,
Tahereh Komeili Movahed
,et al.6
Dec
2024
Letter
Pethidine, Maybe a Rearrangement in the Pharmaceutical Group Is Needed!
Reza Aminnejad*,
*,Ali Solhpour,
Sahar Kavousi Sisi
4
Dec
2024
Research Article
Modulating the Biliverdin Reductase (BVR)/ERK1/2 Axis to Attenuate Oxidative Stress in Rat Arterial Rings
Kuldeepak Sharma*,
Mateja Skufca Sterle,
Hugon Mozina
26
Nov
2024
Correction
Erratum for Ruthenium (II) Complexes Based on Phenanthroline-Tetrazole as Possible Anticancer Agents [Iran J Pharm Res. 2023;22(1): e136738]
Saeid Abaspour,
Behzad Soltani*,
Hamed Hamishehkar,
Moayad Hossaini Sadr
24
Nov
2024
Research Article
The Application of Machine Learning in Predicting the Permeability of Drugs Across the Blood Brain Barrier
Sogand Jafarpour,
Maryam Asefzadeh,
Ehsan Aboutaleb*
18
Nov
2024
Research Article
Malleatin A and B: New Premyrsine-Type Diterpenes from Euphorbia malleata with Cytotoxic Effects Against A2780 Wild and A2780 R-CIS Ovarian Cancer Cell Lines in Mono or Combination Treatment with Cisplatin
Behzad Zolfaghari,
,Forough Akbari,
Sajad Esmaeili,
Mahmoud Aghaei,
,Fatemeh Mosaffa,
,Seyedeh Sara Ghorbanhosseini
,et al.16
Nov
2024
Research Article
Regulation of Apoptosis, Autophagy, and Metastasis by Luteolin in Human Bladder Cancer EJ138 Cells: An Experimental Study
Mohammad Amin Vatankhah,
,Alireza Ziyabakhsh,
,Mohammad Vakili Ojarood*
*13
Nov
2024
Research Article
The Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Liraglutide Regulates Sirtuin-1-Mediated Neutrophil Extracellular Traps to Improve Diabetes-Induced Bone Metabolism Imbalance
Shuai Zhong,
Liangzhi Huang,
Tingting Lin,
Yanyan Li,
Bin Deng,
Dezhi Kong
,et al.12
Nov
2024
Research Article
Apoptotic Impact of Heliox Cold Plasma on a Cervical Cell Line Using Gold Nanoparticle-Doped Graphene Oxide Nanosheets
Mahsa Vatani,
Simzar Hosseinzadeh*,
Amirhossein Sari**,
Hamidreza Ghomi Marzdashti,
Azam Rahimpour,
Roya Fattahi
10
Nov
2024
9
Nov
2024
Research Article
C-Phycocyanin and Phycocyanobilin as a Novel Adjuvant in Hepatitis B Vaccine
Nargess Abdali,
,Reza Tabaripour,
Solaleh Javadi,
,Mehrab Nasirikenari,
Mehdi Birjandi,
,Vahid Siavashi
,et al.5
Nov
2024
Research Article
The COVID-19 Pandemic and the Resilience of the Pharmaceutical Supply Chain: Lessons from Past Experiences and Strategies for the Future
Mohamad Ali Aivazi*,
*,Hamid Reza Rasekh,
Mohammad Peikanpour**,
**,Farzad Peiravian,
,Sajjad Esmaeili,
,Leila Zarei
5
Nov
2024
Research Article
Curcumin-Etoposide Synergy: Unveiling the Molecular Mechanisms of Enhanced Apoptosis and Chemoresistance Attenuation in Breast Cancer
Bahar Jaberian Asl,
,Reza Afarin,
,Mahdi Hatami,
Amineh Dehghani Madiseh,
Mohammadreza Roshanazadeh,
Mojtaba Rashidi*
29
Oct
2024
Review Article
Dipeptidyl Peptidase-4 Inhibitors: A Systematic Review of Structure-Activity Relationship Studies
Maryam Bayanati,
,Mohammad Ismail Mahboubi Rabbani,
Shirin Sirous Kabiri,
Bahareh Mir,
Elham Rezaee,
,Sayyed Abbas Tabatabai*
*29
Oct
2024
Review Article
Dual COX-2/TNF-α Inhibitors as Promising Anti-inflammatory and Cancer Chemopreventive Agents: A Review
Mobina Tajdari,
,Amirreza Peyrovinasab,
,Maryam Bayanati,
Mohammad Ismail Mahboubi Rabbani,
Amir Hossein Abdolghaffari,
Afshin Zarghi*
*28
Oct
2024
Expressions of Concern
Expression of Concern for Paraquat Exposure Up-regulates Cyclooxygenase-2 in the Lungs, Liver, and Kidneys in Rats [Iran J Pharm Res. 2013; 12(4): e125760]
Editor-in-Chief IJPR*
15
Oct
2024
Review Article
Advancements and Applications of Artificial Intelligence in Pharmaceutical Sciences: A Comprehensive Review
Negar Mottaghi-Dastjerdi*,
*,Mohammad Soltany-Rezaee-Rad
14
Oct
2024
Research Article
Efficacy of Clindamycin in Preventing Abortion and Vertical Transmission of Toxoplasma gondii (PRU Strain) Infection in Pregnant BALB/c Mice
Mitra Sadeghi,
Seyed Abdollah Hosseini,
,Shahabeddin Sarvi,
,Pedram Ebrahimnejad,
Hossein Asgarian Omran,
,Zohreh Zare
,et al.13
Oct
2024
Research Article
Dendrosomal Curcumin Showed Cytotoxic Effects on Breast Cancer Cell Line by Inducing Mitochondrial Apoptosis Pathway and Cell Division Arrest
Houriye Abbasi,
Fatemeh Hosseinkhani,
Bahareh Imani Fouladi,
Siroos Tarighi,
Majid Sadeghizadeh,
Maryam Montazeri*
9
Oct
2024
Research Article
Anti-fibrotic Potential of WJ-MSC Exosomes in Liver Fibrosis: Mechanistic Insights and Dose-Response Efficacy
Azam Khedri,
Mohammadreza Roshanazadeh,
Mahdi Hatami,
Arash Sanaei,
Sahar Saki,
Samaneh Salehipour Bavarsad*
*6
Oct
2024
Research Article
Comparative Evaluation of Aminoguanidine, Semicarbazide and Thiosemicarbazide Treatment for Methylglyoxal-Induced Neurological Toxicity in Experimental Models
Noushin Nikray,
Nikoo Abharian,
Shahin Jafari Ashtiani,
Farzad Kobarfard,
,Mehrdad Faizi*
*24
Sep
2024
Research Article
Synergistic Interaction of Chloroquine with Artemisia kopetdaghensis Semipolar Extract Against Plasmodium berghei: Histopathological and Immunological Studies in a Mouse Model
Roya Amirian,
Mustafa Ghanadian,
,Hamed Fouladseresht,
Azar Baradaran,
Seyed Mohammad Abtahi,
Bahareh Basirpour
,et al.17
Sep
2024
Research Article
24-Dehydrocholesterol Reductase Facilitates Cisplatin Resistance of Non-small Cell Lung Cancer via Repressing Reactive Oxygen Species/Ferroptosis Pathway
Ce Qin*,
*,Jun Yuan,
Rui Zhang,
Li Liu,
Yue-Song Ban
16
Sep
2024
Research Article
Antiproliferative and Pro-apoptotic Activities of Tournefortia mutabilis vent. Leaves on the Human Breast Adenocarcinoma Cell Line (MCF-7)
Zoila Mora-Guzmán,
Luis Bernardo Flores-Cotera,
Eduardo Pérez-Campos,
Rebeca López-Marure,
Delia Soto-Castro,
Felipe Alonso Masso-Rojas
,et al.16
Sep
2024
Research Article
The Relationship Between Weight Indices and Blood Levels of Immunosuppressive Drugs in Renal Transplant Recipients
Shirinsadat Badri,
,Bozorgmehr Dadkhah-Tehrani,
Abdolamir Atapour,
,Shahrzad Shahidi,
,Mojgan Mortazavi,
Tahereh Gholipourshahraki*
*16
Sep
2024
Research Article
Cost-Utility Analysis of Erenumab Compared to Topiramate for Preventive Therapy of Migraine in Iran
Hosein Mollaee,
Sadra Nadimi Parashkouhi,
Behzad Fatemi,
,Meysam Seyedifar,
,Fatemeh Soleymani*
*15
Sep
2024
Research Article
Inhibitory Effects of Marrubium vulgare L. Extract on the Female Hormones Based on Bioautography-HPTLC-MS
Sahar Hassannejad,
Abdulghany O. I. Sarmamy,
Fateme Mirzajani*
*15
Sep
2024
Research Article
Therapeutic Potential of Crocin and Nobiletin in a Mouse Model of Dry Eye Disease: Modulation of the Inflammatory Response and Protection of the Ocular Surface
Ahmad Habibian Sezavar,
,Seyed Nasser Ostad,
,Yazdan Hasani Nourian*,
*,Hossein Aghamollaei**
**15
Sep
2024
Research Article
The Role of Zinc Supplementation in Alleviating Inflammatory Biomarkers in Patients Undergoing Hemodialysis: A Randomized Placebo Controlled, Crossover Trial
Shayan Mastoor-Tehrani,
,Fariba Samadian,
,Hadi Esmaily,
,Alireza Kargar,
,Nasim Markazi,
Shideh Anvari
,et al.11
Sep
2024
Research Article
A Preliminary Study to Evaluate the Immune Response to a Booster Dose of the Adult Tetanus-Diphtheria Vaccine (Td) Available in Iran
Sepideh Noorian,
,Negar Mottaghi-Dastjerdi*,
*,Mohammad Soltany-Rezaee-Rad,
,Hamed Montazeri,
Masoumeh Baghaei,
Mohammad-Javad Niazi
11
Sep
2024
Research Article
Selection and Characterization of a DNA Aptamer Recognizing High Mobility Group Box 1 Protein (HMGB1) and Enhancing Its Pro-inflammatory Activity
Hanchao Li,
Wengang Sun,
Yanhua Huang,
Qian Li,
Hong Tian,
Zhiming Hao
,et al.27
Aug
2024
20
Aug
2024
Research Article
Saliva Lipids May Determine Alprazolam Toxicity: An FTIR Study
Arezou Mahdavinejad,
Shahin Shadnia,
Kiana Farhadinejad,
Golrokh Farnam,
,Farshad H. Shirazi*
*4
Aug
2024
Research Article
Establishment of an HPLC Fingerprint and Cluster Analysis for Miao Ethnic Medicine Osbeckia opipara
Qiang Su,
,Ting Su,
Yun Lu,
Min Wu,
Song Huang,
Shouneng Chen
,et al.3
Jul
2024
Research Article
The Effects of ThymusCaramanicus Jalas Extract and Its Main Constituent Carvacrol Against Cisplatin-Induced Nephrotoxicity in Mice
Amin Hassanshahi,
Ayat Kaeedi,
,Mohammad Reza Rahmani,
,Jalal Hassanshahi*
*22
Jun
2024
Research Article
The Protective Effects of Pistacia Atlantica Gum in a Rat Model of Aluminum Chloride-Induced Alzheimer’s Disease via Affecting BDNF and NF-kB
Mohammad Mehdi Gravandi,
,Seyede Zahra Hosseini,
Seyede Darya Alavi,
Tayebeh Noori,
Antoni Sureda,
Roshanak Amirian
,et al.11
Jun
2024
Research Article
Insulin and TLR4 Inhibitor Improve Motor Impairments in a Rat Model of Parkinson’s Disease
Fatemeh Hemmati,
Neda Valian,
Abolhassan Ahmadiani,
Zahurin Mohamed,
Raymond Azman Ali,
Norlinah Mohamed Ibrahim
,et al.2
Jun
2024
Research Article
Administering Fluralaner in Drinking Water for Treatment of Dermanyssus gallinae Infestation in Hy-Line W80 Laying Hens
MohammadReza Raeisi*,
Abdolkarim Zamani Moghaddam,
Seyyed Sattar Tohidifar,
Maryam Malekan
2
Jun
2024
Research Article
Bioinformatics and Gene Expression Omnibus Analysis of Key Candidate Genes and Pathways Associated with Femoral Head Necrosis
Yuanjing Ding,
Yuxia Ma,
Heng Yan,
Enshui Zhang*
*2
Jun
2024
Research Article
RadioLabeling of the Mutant form of Anti-PlGF Nanobody by 99mTc-Tricarbonyl
Tahereh Rezazadeh,
Akram Sadat Tabatabaee Bafroee,
,Soraya Shahhosseini,
Safura Jokar,
Abolfazl Hasanramezani,
Roghaye Arezumand*
1
Jun
2024
Systematic Review
Systematic Review of Patient Preference Studies in Non-metastatic Breast Cancer Adjuvant Medication Therapy: Attribute Selection
Ali Homayouni,
,Shekoufeh Nikfar,
,Fariborz Mokarian Rajabi,
,Mona Nili,
,Kimberly M. Kelly,
,Akbar Abdollahiasl*
*29
May
2024
Research Article
Investigation of the Cytotoxic and Antiproliferative Effects of Liposomal Daunorubicin on Human Colorectal Cancer (HCT116) Cell Line
Noorulhuda Alaa Hadi-al-Ward,
,Mehdi Ebrahimi*,
*,Shohre Zare Karizi
18
May
2024
Research Article
Time-Dependent Molecular Changes Following MDMA-Induced Nephrotoxicity
Mehrdad Roghani,
,Ravieh Golchoobian*,
Maryam Mohammadian,
Farzane Shanehbandpour-Tabari,
Zahra Salehi,
Saba Gilaki-Bisheh
14
May
2024
Research Article
Cost-Effectiveness Analysis of Pharmacogenomics-Guided Versus Standard Dosing of Warfarin in Patients with Mechanical Prosthetic Heart Valve
Homa Hemati,
,Marzieh Nosrati,
,Mandana Hasanzad,
,Parham Rahmani,
Soroush Fariman,
,Mohadese Sarabi
,et al.11
May
2024
Research Article
Aortic Injury Induced by Benzo(a)pyrene and Atherogenic Diet Increased Hepatic FGF21 Expression in C57BL/6J Mice
Farzane Shanehbandpour-Tabari,
,Fatemeh Gholamnataj,
,Nahid Neamati,
,Ebrahim Zabihi,
,Farideh Feizi,
,Hadi Parsian*
*11
May
2024
Research Article
PAG Masked Protective Physical Exercise-Induced High H2S Levels in 5/6 Nephrectomized Rats
Behjat Seifi,
,Mehri Kadkhodaei*,
*,Enayatollah Bakhshi,
,Abdollah Sajedizadeh,
Mina Ranjbaran,
,Mahdi Hajiaqaei
7
May
2024
Research Article
Sub-chronic Toxicity Study of Heracleumlasiopetalum Extract Towards Healthy Sprague Dawley Rats
Enas Sabah Hassan,
Heshu Rahman*,
*,Shirwan Hamasalih Omer
28
Apr
2024
Research Article
Comparison of the Areas Under the Curve of Vancomycin Continuous vs. Intermittent Infusion in Critically Ill Pediatrics: A Randomized Clinical Trial
Baran Roshan N.S.,
,Bahador Mirrahimi*,
*,Farhad Najmeddin,
,Seyedeh Narjes Ahmadizadeh,
,Azita Behzad,
,Seyedeh Masumeh Hashemi
,et al.20
Apr
2024
Research Article
Untargeted LC/HRMS Metabolomics Analysis and Anticancer Activity Assay on MCF-7 and A549 Cells from Coleus amboinicus Lour Leaf Extract
Kasta Gurning,
,Suratno Suratno,
,Endang Astuti,
,Winarto Haryadi*
*8
Apr
2024
Research Article
Optimization of the Synthesis and Radiolabeling of ZIF-8 Nanoparticles
Mahnaz Ahmadi*,
*,Elham Asadian,
Mona Mosayebnia,
Simin Dadashzadeh,
,Soraya Shahhosseini,
Fateme Ghorbani-Bidkorpeh
8
Apr
2024
Research Article
Non-clinical Safety Evaluation of Camelina Oil: Acute and 12-Week Oral Toxicities
Kambiz Varmira,
Danial Kahrizi,
Azarm Sanjari,
Khodabakhsh Rashidi,
Leila Hosseinzadeh*,
*,Niloufar Amin
,et al.6
Apr
2024
Research Article
Understanding the Molecular Landscape of Endometriosis: A Bioinformatics Approach to Uncover Signaling Pathways and Hub Genes
Junhua Tian,
,Xiaochun Liu*
*31
Mar
2024
Research Article
Mitochondrial Transplantation Alleviates Doxorubicin-Induced Toxicity in Rat Renal Cells
Enayatollah Seydi,
Mahsa Andalib,
Sana Yaghoubi,
Amir Fakhri,
Jale Yuzugulen,
Abdollah Arjmand**
,et al.30
Mar
2024
Research Article
Signal-On Fluorescence Biosensor for Detection of miRNA-21 Based on ROX labeled Specific Stem-Loop Probe
Somayeh Heidarian,
Laya Takbiri Osgoei*,
*,Shohreh Zare Karizi,
,Jafar Amani,
,Sedigheh Arbabian
28
Mar
2024
Research Article
Development and Ex-Vivo Skin Permeation of Sildenafil Citrate Microemulsion System for Transdermal Delivery
Nasibeh Jamali,
,Eskandar Moghimipour,
,Fatemeh Nikpour,
Anayatollah Salimi*
*26
Mar
2024
Research Article
Renal Fibrosis and Oxidative Stress Induced by Silica Nanoparticles in Male Rats and Its Molecular Mechanisms
Bakhta Aouey,
Khadija Boukholda,
Alin Ciobica*,
Vasile Burlui,
Rachid Soulimani,
Fatiha Chigr
,et al.24
Mar
2024
Research Article
Crocin-Phospholipid Complex: Molecular Docking, Molecular Dynamics Simulation, Preparation, Characterization, and Antioxidant Activity
Yasaman Rezaee,
Elham Rezaee,
,Leila Karami,
Maryam Torshabi,
,Azadeh Haeri*
*9
Mar
2024
Brief Report
Cassia angustifolia Vahl. Leaves: Determination of Total Phenolic and Sennoside Contents of Different Fractions in Comparison with Their α- Glucosidase and Tyrosinase Inhibitory Effects
Dina Morid Ahmadi,
Somayeh Mojtabavi,
Shima Ghadami,
Mahdieh Eftekhari,
Mohammad Reza Shams Ardekani,
Mohammad Ali Faramarzi
,et al.9
Mar
2024
Research Article
Therapeutic Effects of Pimpinella anisum Fruit Extract on Polycystic Ovary Syndrome in a Rat Model: Emerging Role of Inflammatory Responses and Oxidative Stress
Masoomeh Dadkhah,
,Negin Gholizadeh,
,Ramin Nasimi Doost Azgomi,
,Shahnaz Hosseinzadeh,
,Sanaz Hamedeyazdan,
,Khadijeh Haghighat
,et al.9
Mar
2024
Research Article
Genomic Characteristics of an Extensive-Drug-Resistant Clinical Escherichia coli O99 H30 ST38 Recovered from Wound
Ali A Dashti*,
Leila Vali,
Sara Shamsah,
Mehrez Jadaon,
Sherief ElShazly
27
Feb
2024
Research Article
A Long-Lasting Triamcinolone-Loaded Microneedle Patch for Prolonged Dermal Delivery
Nasrin Zarei Chamgordani,
,Sasan Asiaei,
,Fatemeh Ghorbani-Bidkorpeh,
,Masoud Babaee Foroutan,
Mostafa Dahmardehei,
Hamid Reza Moghimi*
*27
Feb
2024
21
Feb
2024
Research Article
Efficacy and Safety of a DOAC Compared to Unfractionated Heparin and A Low Molecular Weight Heparin in the Prevention of Thromboembolism in Hematopoietic Stem Cell Transplant Recipients
Saeed Azimi,
,Abbas Hajifathali,
,Sayeh Parkhideh,
Jamshid Salamzadeh,
,Bardia Rahmati-Kamel,
Farzaneh Dastan
,et al.17
Feb
2024
Research Article
Design and Characterization of an Osmotic Pump System for Optimal Feeding and pH Control in E. coli Culture to Increase Biomass
Saeedeh Abedin,
,Javad Ranjbari,
,Azadeh Haeri,
,Hossein Vahidi,
Hamid Reza Moghimi*
*